Gene Card
Best human hits
DHTKD1; OGDH; OGDHL
Species
Unique Gene ID
Cisavi.g00011297
Gene Model ID
Cisavi.CG.ENS81.R9.3659410-3671023
Location
R9:3659409..3671023
Transcript Models and Sequences
Cisavi.CG.ENS81.R9.3659410-3671023.19374.t
Cisavi.CG.ENS81.R9.3659410-3671023.19375.t
Cisavi.CG.ENS81.R9.3659410-3671023.19376.t
Cisavi.CG.ENS81.R9.3659410-3671023.19377.t
Cisavi.CG.ENS81.R9.3659410-3671023.19378.t
Cisavi.CG.ENS81.R9.3659410-3671023.19379.t
Cisavi.CG.ENS81.R9.3659410-3671023.19380.t
Cisavi.CG.ENS81.R9.3659410-3671023.19381.t
Cisavi.CG.ENS81.R9.3659410-3671023.19382.t
Cisavi.CG.ENS81.R9.3659410-3671023.19383.t
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Transketolase-like_Pyr-bd | Pfam | Transketolase-like, pyrimidine-binding domain |
KGD_C | Pfam | Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal |
2oxoglutarate_DH_E1 | PIRSF | 2-oxoglutarate dehydrogenase E1 component |
2oxoglutarate_DH_E1 | PANTHER | 2-oxoglutarate dehydrogenase E1 component |
DH_E1 | Pfam | Dehydrogenase, E1 component |
Transketolase-like_Pyr-bd | SMART | Transketolase-like, pyrimidine-binding domain |
2oxoglutarate_DH_E1 | TIGRFAM | 2-oxoglutarate dehydrogenase E1 component |
THDP-binding | SUPERFAMILY | Thiamin diphosphate-binding fold |
2-oxogl_dehyd_N | Pfam | 2-oxoglutarate dehydrogenase E1 component, N-terminal domain |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
oxoglutarate dehydrogenase (succinyl-transferring) activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
generation of precursor metabolites and energy | Hs | biological process |
glycolytic process | Hs | biological process |
tricarboxylic acid cycle | Hs | biological process |
2-oxoglutarate metabolic process | Hs | biological process |
succinyl-CoA metabolic process | Hs | biological process |
NADH metabolic process | Hs | biological process |
metabolic process | Hs | biological process |
oxidoreductase activity | Hs | molecular function |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function |
cerebellar cortex development | Hs | biological process |
thalamus development | Hs | biological process |
thiamine pyrophosphate binding | Hs | molecular function |
heat shock protein binding | Hs | molecular function |
mitochondrial membrane | Hs | cellular component |
oxoglutarate dehydrogenase (NAD+) activity | Hs | molecular function |
oxoglutarate dehydrogenase complex | Hs | cellular component |
metal ion binding | Hs | molecular function |
chaperone binding | Hs | molecular function |
oxidation-reduction process | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
oxoglutarate dehydrogenase (succinyl-transferring) activity | Hs | molecular function | 1365 | 0.0 |
protein binding | Hs | molecular function | 1307 | 0.0 |
nucleus | Hs | cellular component | 1365 | 0.0 |
mitochondrion | Hs | cellular component | 1365 | 0.0 |
mitochondrial matrix | Hs | cellular component | 1365 | 0.0 |
oxidoreductase activity | Hs | molecular function | 1365 | 0.0 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function | 1365 | 0.0 |
thiamine pyrophosphate binding | Hs | molecular function | 1365 | 0.0 |
heat shock protein binding | Hs | molecular function | 1365 | 0.0 |
mitochondrial membrane | Hs | cellular component | 1365 | 0.0 |
oxoglutarate dehydrogenase (NAD+) activity | Hs | molecular function | 1365 | 0.0 |
oxoglutarate dehydrogenase complex | Hs | cellular component | 1365 | 0.0 |
metal ion binding | Hs | molecular function | 1365 | 0.0 |
chaperone binding | Hs | molecular function | 1365 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
oxoglutarate dehydrogenase (succinyl-transferring) activity | PIRSF | molecular function | 0.0 |
tricarboxylic acid cycle | PIRSF | biological process | 0.0 |
metabolic process | Pfam | biological process | 1.2E-77 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Pfam | molecular function | 1.2E-77 |
thiamine pyrophosphate binding | PIRSF | molecular function | 0.0 |
oxidation-reduction process | PIRSF | biological process | 0.0 |