Gene Card
Best human hits
PDE11A; PDE2A; PDE9A
Species
Unique Gene ID
Haaura.g00003126
Gene Model ID
Haaura.CG.MTP2014.S190.g03126
Location
S190:85304..88462
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
5 results
| IPR Term | Analysis | Definition |
|---|---|---|
| HD/PDEase_dom | CDD | HD/PDEase domain |
| PDEase_CS | ProSitePatterns | 3'5'-cyclic nucleotide phosphodiesterase, conserved site |
| PDEase | PRINTS | 3'5'-cyclic nucleotide phosphodiesterase |
| PDEase_catalytic_dom_sf | Gene3D | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily |
| PDEase_catalytic_dom | Pfam | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain |
| GO Term | Annotation Origin | Type |
|---|
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
35 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 107 | 2.06e-25 |
| catalytic activity | Hs | molecular function | 113 | 1.93e-27 |
| cyclic-nucleotide phosphodiesterase activity | Hs | molecular function | 113 | 1.93e-27 |
| 3',5'-cyclic-nucleotide phosphodiesterase activity | Hs | molecular function | 181 | 2.79e-52 |
| 3',5'-cyclic-AMP phosphodiesterase activity | Hs | molecular function | 113 | 1.93e-27 |
| cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | Hs | molecular function | 113 | 1.93e-27 |
| calcium channel activity | Hs | molecular function | 107 | 2.06e-25 |
| protein binding | Hs | molecular function | 181 | 2.79e-52 |
| intracellular | Hs | cellular component | 181 | 2.79e-52 |
| nucleus | Hs | cellular component | 107 | 2.06e-25 |
| cytoplasm | Hs | cellular component | 181 | 2.79e-52 |
| mitochondrion | Hs | cellular component | 107 | 2.06e-25 |
| mitochondrial outer membrane | Hs | cellular component | 107 | 2.06e-25 |
| mitochondrial inner membrane | Hs | cellular component | 107 | 2.06e-25 |
| mitochondrial matrix | Hs | cellular component | 107 | 2.06e-25 |
| endoplasmic reticulum | Hs | cellular component | 181 | 2.79e-52 |
| Golgi apparatus | Hs | cellular component | 181 | 2.79e-52 |
| cytosol | Hs | cellular component | 181 | 2.79e-52 |
| plasma membrane | Hs | cellular component | 181 | 2.79e-52 |
| phosphoric diester hydrolase activity | Hs | molecular function | 181 | 2.79e-52 |
| drug binding | Hs | molecular function | 107 | 2.06e-25 |
| membrane | Hs | cellular component | 181 | 2.79e-52 |
| hydrolase activity | Hs | molecular function | 181 | 2.79e-52 |
| cAMP binding | Hs | molecular function | 107 | 2.06e-25 |
| cGMP binding | Hs | molecular function | 113 | 1.93e-27 |
| TPR domain binding | Hs | molecular function | 107 | 2.06e-25 |
| ruffle membrane | Hs | cellular component | 181 | 2.79e-52 |
| sarcolemma | Hs | cellular component | 181 | 2.79e-52 |
| presynaptic membrane | Hs | cellular component | 107 | 2.06e-25 |
| protein homodimerization activity | Hs | molecular function | 107 | 2.06e-25 |
| cell projection | Hs | cellular component | 181 | 2.79e-52 |
| perikaryon | Hs | cellular component | 181 | 2.79e-52 |
| metal ion binding | Hs | molecular function | 181 | 2.79e-52 |
| 3',5'-cyclic-GMP phosphodiesterase activity | Hs | molecular function | 181 | 2.79e-52 |
| perinuclear region of cytoplasm | Hs | cellular component | 181 | 2.79e-52 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| 3',5'-cyclic-nucleotide phosphodiesterase activity | Gene3D | molecular function | 1.6E-61 |
| signal transduction | Gene3D | biological process | 1.6E-61 |
| phosphoric diester hydrolase activity | PRINTS | molecular function | 1.1E-9 |
