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Gene Card

Best human hits

LRP4; LRP6

Species

H.aurantium

Unique Gene ID

Haaura.g00000701

Gene Model ID

Haaura.CG.MTP2014.S24.g00701

Location

S24:92992..105610

Transcript Models and Sequences

  Haaura.CG.MTP2014.S24.g00701.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

20 results

IPR Term Analysis Definition
LDLR_classB_rpt ProSiteProfiles LDLR class B repeat
LDL_receptor-like_sf SUPERFAMILY LDL receptor-like superfamily
cEGF Pfam Complement Clr-like EGF domain
LDrepeatLR_classA_rpt CDD Low-density lipoprotein (LDL) receptor class A repeat
EGF-like_dom ProSiteProfiles EGF-like domain
6-blade_b-propeller_TolB-like Gene3D Six-bladed beta-propeller, TolB-like
LDrepeatLR_classA_rpt ProSiteProfiles Low-density lipoprotein (LDL) receptor class A repeat
EGF_Ca-bd_CS ProSitePatterns EGF-like calcium-binding, conserved site
EGF-like_dom SMART EGF-like domain
LDLR_classB_rpt Pfam LDLR class B repeat
EGF-type_Asp/Asn_hydroxyl_site ProSitePatterns EGF-type aspartate/asparagine hydroxylation site
LDLR_classB_rpt SMART LDLR class B repeat
LDrepeatLR_classA_rpt Pfam Low-density lipoprotein (LDL) receptor class A repeat
LDLR_class-A_CS ProSitePatterns Low-density lipoprotein (LDL) receptor class A, conserved site
LDrepeatLR_classA_rpt PRINTS Low-density lipoprotein (LDL) receptor class A repeat
LRP4 PANTHER Low-density lipoprotein receptor-related protein 4
Growth_fac_rcpt_cys_sf SUPERFAMILY Growth factor receptor cysteine-rich domain superfamily
EGF-like_Ca-bd_dom SMART EGF-like calcium-binding domain
EGF-like_CS ProSitePatterns EGF-like, conserved site
LDrepeatLR_classA_rpt SMART Low-density lipoprotein (LDL) receptor class A repeat

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

49 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
kidney development Hs biological process
regulation of protein phosphorylation Hs biological process
calcium ion binding Hs molecular function
protein binding Hs molecular function
plasma membrane Hs cellular component
endocytosis Hs biological process
multicellular organism development Hs biological process
protein localization Hs biological process
dorsal/ventral pattern formation Hs biological process
proximal/distal pattern formation Hs biological process
cell surface Hs cellular component
postsynaptic density Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
Wnt signaling pathway Hs biological process
flotillin complex Hs cellular component
Wnt-protein binding Hs molecular function
cell differentiation Hs biological process
negative regulation of Wnt signaling pathway Hs biological process
negative regulation of ossification Hs biological process
embryonic limb morphogenesis Hs biological process
dendrite Hs cellular component
BMP signaling pathway Hs biological process
receptor tyrosine kinase binding Hs molecular function
neuromuscular junction Hs cellular component
apolipoprotein binding Hs molecular function
protein homodimerization activity Hs molecular function
Wnt-activated receptor activity Hs molecular function
neuronal cell body Hs cellular component
receptor clustering Hs biological process
receptor complex Hs cellular component
Wnt signaling pathway involved in dorsal/ventral axis specification Hs biological process
animal organ development Hs biological process
dendrite morphogenesis Hs biological process
anatomical structure development Hs biological process
positive regulation of peptidyl-tyrosine phosphorylation Hs biological process
negative regulation of axonogenesis Hs biological process
synapse organization Hs biological process
synaptic growth at neuromuscular junction Hs biological process
protein heterotetramerization Hs biological process
limb development Hs biological process
regulation of canonical Wnt signaling pathway Hs biological process
skeletal muscle acetylcholine-gated channel clustering Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
synaptic membrane Hs cellular component
postsynaptic membrane assembly Hs biological process
presynaptic membrane assembly Hs biological process
scaffold protein binding Hs molecular function
positive regulation of skeletal muscle acetylcholine-gated channel clustering Hs biological process

GO (Blast)

38 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
low-density lipoprotein receptor activity Hs molecular function 876 0.0
receptor binding Hs molecular function 876 0.0
frizzled binding Hs molecular function 876 0.0
calcium ion binding Hs molecular function 1642 0.0
protein binding Hs molecular function 1642 0.0
extracellular region Hs cellular component 876 0.0
early endosome Hs cellular component 876 0.0
endoplasmic reticulum Hs cellular component 876 0.0
Golgi apparatus Hs cellular component 876 0.0
plasma membrane Hs cellular component 1642 0.0
caveola Hs cellular component 876 0.0
cell surface Hs cellular component 1642 0.0
postsynaptic density Hs cellular component 1642 0.0
membrane Hs cellular component 1642 0.0
integral component of membrane Hs cellular component 1642 0.0
flotillin complex Hs cellular component 1642 0.0
Wnt-protein binding Hs molecular function 1642 0.0
kinase inhibitor activity Hs molecular function 876 0.0
toxin transporter activity Hs molecular function 876 0.0
dendrite Hs cellular component 1642 0.0
receptor tyrosine kinase binding Hs molecular function 1642 0.0
cytoplasmic vesicle Hs cellular component 876 0.0
neuromuscular junction Hs cellular component 1642 0.0
early endosome membrane Hs cellular component 876 0.0
apolipoprotein binding Hs molecular function 1642 0.0
identical protein binding Hs molecular function 876 0.0
protein homodimerization activity Hs molecular function 1642 0.0
Wnt-activated receptor activity Hs molecular function 1642 0.0
neuronal cell body Hs cellular component 1642 0.0
receptor complex Hs cellular component 1642 0.0
membrane raft Hs cellular component 876 0.0
synapse Hs cellular component 876 0.0
coreceptor activity involved in Wnt signaling pathway Hs molecular function 876 0.0
synaptic membrane Hs cellular component 1642 0.0
scaffold protein binding Hs molecular function 1642 0.0
coreceptor activity involved in canonical Wnt signaling pathway Hs molecular function 876 0.0
Wnt-Frizzled-LRP5/6 complex Hs cellular component 876 0.0
Wnt signalosome Hs cellular component 876 0.0

GO (InterProScan)

5 results

GO Term Analysis Type e-value
calcium ion binding SMART molecular function 2.7E-8
protein binding PRINTS molecular function 3.7E-36
BMP signaling pathway PANTHER biological process 0.0
animal organ development PANTHER biological process 0.0
regulation of canonical Wnt signaling pathway PANTHER biological process 0.0

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