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GENE CARD

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Gene Card

Best human hits

EZR; MSN; RDX

Species

H.aurantium

Unique Gene ID

Haaura.g00004464

Gene Model ID

Haaura.CG.MTP2014.S346.g04464

Location

S346:42787..50476

Transcript Models and Sequences

  Haaura.CG.MTP2014.S346.g04464.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

18 results

IPR Term Analysis Definition
FERM_PH-like_C Pfam FERM, C-terminal PH-like domain
Band_41_domain SMART Band 4.1 domain
Ez/rad/moesin-like PRINTS Ezrin/radixin/moesin-like
FERM/acyl-CoA-bd_prot_sf Gene3D FERM/acyl-CoA-binding protein superfamily
FERM_N Pfam FERM, N-terminal
FERM_CS ProSitePatterns FERM conserved site
FERM_2 SUPERFAMILY FERM superfamily, second domain
FERM_domain ProSiteProfiles FERM domain
FERM_central Pfam FERM central domain
Moesin_tail_sf SUPERFAMILY Moesin tail domain superfamily
FERM_PH-like_C SMART FERM, C-terminal PH-like domain
ERM PIRSF Ezrin/radixin/moesin
ERM_C_dom Pfam Ezrin/radixin/moesin, C-terminal
Band_41_domain PRINTS Band 4.1 domain
FERM_central CDD FERM central domain
PH-like_dom_sf Gene3D PH-like domain superfamily
Ubiquitin-like_domsf SUPERFAMILY Ubiquitin-like domain superfamily
Moesin_tail_sf Gene3D Moesin tail domain superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

122 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
fibrillar center Hs cellular component
ruffle Hs cellular component
immunological synapse Hs cellular component
uropod Hs cellular component
sphingosine-1-phosphate signaling pathway Hs biological process
RNA binding Hs molecular function
double-stranded RNA binding Hs molecular function
actin binding Hs molecular function
receptor binding Hs molecular function
structural constituent of cytoskeleton Hs molecular function
protein binding Hs molecular function
extracellular space Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
endosome Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
actin filament Hs cellular component
plasma membrane Hs cellular component
microvillus Hs cellular component
brush border Hs cellular component
cell-cell adherens junction Hs cellular component
focal adhesion Hs cellular component
cell cortex Hs cellular component
cytoskeleton organization Hs biological process
cytoskeletal anchoring at plasma membrane Hs biological process
axon guidance Hs biological process
microtubule binding Hs molecular function
protein C-terminus binding Hs molecular function
cytoskeletal protein binding Hs molecular function
regulation of cell shape Hs biological process
regulation of cell size Hs biological process
cell surface Hs cellular component
positive regulation of gene expression Hs biological process
protein kinase A signaling Hs biological process
actin cytoskeleton Hs cellular component
membrane Hs cellular component
basolateral plasma membrane Hs cellular component
apical plasma membrane Hs cellular component
extrinsic component of membrane Hs cellular component
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
protein domain specific binding Hs molecular function
lamellipodium Hs cellular component
microvillus assembly Hs biological process
filopodium Hs cellular component
T-tubule Hs cellular component
positive regulation of cell migration Hs biological process
midbody Hs cellular component
epithelial cell differentiation Hs biological process
cortical cytoskeleton Hs cellular component
cortical actin cytoskeleton Hs cellular component
astral microtubule organization Hs biological process
pseudopodium Hs cellular component
microvillus membrane Hs cellular component
actin cytoskeleton reorganization Hs biological process
receptor internalization Hs biological process
vesicle Hs cellular component
cleavage furrow Hs cellular component
regulation of actin filament bundle assembly Hs biological process
stereocilium Hs cellular component
regulation of Rap protein signal transduction Hs biological process
ruffle membrane Hs cellular component
macromolecular complex Hs cellular component
negative regulation of homotypic cell-cell adhesion Hs biological process
protein kinase A catalytic subunit binding Hs molecular function
protein kinase A regulatory subunit binding Hs molecular function
negative regulation of GTPase activity Hs biological process
cellular protein complex localization Hs biological process
establishment or maintenance of apical/basal cell polarity Hs biological process
ciliary basal body Hs cellular component
positive regulation of multicellular organism growth Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
cell projection Hs cellular component
regulation of GTPase activity Hs biological process
myelin sheath Hs cellular component
cortical microtubule organization Hs biological process
cell body Hs cellular component
microspike Hs cellular component
S100 protein binding Hs molecular function
plasma membrane raft Hs cellular component
membrane raft Hs cellular component
apical protein localization Hs biological process
apical part of cell Hs cellular component
establishment of protein localization Hs biological process
establishment of epithelial cell apical/basal polarity Hs biological process
cadherin binding Hs molecular function
negative regulation of cell size Hs biological process
filopodium assembly Hs biological process
phosphatidylinositol-mediated signaling Hs biological process
perinuclear region of cytoplasm Hs cellular component
positive regulation of protein secretion Hs biological process
cell adhesion molecule binding Hs molecular function
negative regulation of T cell receptor signaling pathway Hs biological process
leukocyte migration Hs biological process
actin filament binding Hs molecular function
barbed-end actin filament capping Hs biological process
actin filament bundle assembly Hs biological process
protein kinase A binding Hs molecular function
ATPase binding Hs molecular function
cell tip Hs cellular component
establishment of centrosome localization Hs biological process
actin filament capping Hs biological process
establishment of endothelial barrier Hs biological process
extracellular exosome Hs cellular component
negative regulation of ERK1 and ERK2 cascade Hs biological process
invadopodium Hs cellular component
cell periphery Hs cellular component
blood microparticle Hs cellular component
protein localization to plasma membrane Hs biological process
protein localization to cell cortex Hs biological process
astrocyte projection Hs cellular component
Schwann cell microvillus Hs cellular component
disordered domain specific binding Hs molecular function
cytoplasmic side of apical plasma membrane Hs cellular component
positive regulation of G1/S transition of mitotic cell cycle Hs biological process
positive regulation of protein localization to plasma membrane Hs biological process
positive regulation of cellular protein catabolic process Hs biological process
negative regulation of adherens junction organization Hs biological process

GO (Blast)

77 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
fibrillar center Hs cellular component 644 0.0
ruffle Hs cellular component 644 0.0
immunological synapse Hs cellular component 644 0.0
uropod Hs cellular component 644 0.0
RNA binding Hs molecular function 644 0.0
double-stranded RNA binding Hs molecular function 644 0.0
actin binding Hs molecular function 644 0.0
receptor binding Hs molecular function 644 0.0
structural constituent of cytoskeleton Hs molecular function 644 0.0
protein binding Hs molecular function 644 0.0
extracellular space Hs cellular component 644 0.0
intracellular Hs cellular component 644 0.0
nucleus Hs cellular component 644 0.0
cytoplasm Hs cellular component 644 0.0
endosome Hs cellular component 644 0.0
cytosol Hs cellular component 644 0.0
cytoskeleton Hs cellular component 644 0.0
actin filament Hs cellular component 644 0.0
plasma membrane Hs cellular component 644 0.0
microvillus Hs cellular component 644 0.0
brush border Hs cellular component 644 0.0
cell-cell adherens junction Hs cellular component 637 0.0
focal adhesion Hs cellular component 644 0.0
cell cortex Hs cellular component 644 0.0
microtubule binding Hs molecular function 644 0.0
protein C-terminus binding Hs molecular function 644 0.0
cytoskeletal protein binding Hs molecular function 644 0.0
cell surface Hs cellular component 644 0.0
actin cytoskeleton Hs cellular component 644 0.0
membrane Hs cellular component 644 0.0
basolateral plasma membrane Hs cellular component 644 0.0
apical plasma membrane Hs cellular component 644 0.0
extrinsic component of membrane Hs cellular component 644 0.0
enzyme binding Hs molecular function 644 0.0
protein kinase binding Hs molecular function 644 0.0
protein domain specific binding Hs molecular function 644 0.0
lamellipodium Hs cellular component 637 0.0
filopodium Hs cellular component 644 0.0
T-tubule Hs cellular component 644 0.0
midbody Hs cellular component 637 0.0
cortical cytoskeleton Hs cellular component 644 0.0
cortical actin cytoskeleton Hs cellular component 637 0.0
pseudopodium Hs cellular component 644 0.0
microvillus membrane Hs cellular component 644 0.0
vesicle Hs cellular component 644 0.0
cleavage furrow Hs cellular component 637 0.0
stereocilium Hs cellular component 637 0.0
ruffle membrane Hs cellular component 644 0.0
macromolecular complex Hs cellular component 644 0.0
protein kinase A catalytic subunit binding Hs molecular function 644 0.0
protein kinase A regulatory subunit binding Hs molecular function 644 0.0
ciliary basal body Hs cellular component 644 0.0
identical protein binding Hs molecular function 644 0.0
protein homodimerization activity Hs molecular function 637 0.0
cell projection Hs cellular component 644 0.0
myelin sheath Hs cellular component 644 0.0
cell body Hs cellular component 644 0.0
microspike Hs cellular component 644 0.0
S100 protein binding Hs molecular function 644 0.0
plasma membrane raft Hs cellular component 644 0.0
membrane raft Hs cellular component 644 0.0
apical part of cell Hs cellular component 644 0.0
cadherin binding Hs molecular function 644 0.0
perinuclear region of cytoplasm Hs cellular component 644 0.0
cell adhesion molecule binding Hs molecular function 644 0.0
actin filament binding Hs molecular function 644 0.0
protein kinase A binding Hs molecular function 644 0.0
ATPase binding Hs molecular function 644 0.0
cell tip Hs cellular component 644 0.0
extracellular exosome Hs cellular component 644 0.0
invadopodium Hs cellular component 644 0.0
cell periphery Hs cellular component 644 0.0
blood microparticle Hs cellular component 644 0.0
astrocyte projection Hs cellular component 644 0.0
Schwann cell microvillus Hs cellular component 644 0.0
disordered domain specific binding Hs molecular function 644 0.0
cytoplasmic side of apical plasma membrane Hs cellular component 644 0.0

GO (InterProScan)

3 results

GO Term Analysis Type e-value
actin binding PIRSF molecular function 2.0E-241
cytoskeleton ProSiteProfiles cellular component 78.099
cytoskeletal protein binding PRINTS molecular function 7.0E-84