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GENE CARD

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Gene Card

Best human hits

MLH1; PMS1; PMS2

Species

H.aurantium

Unique Gene ID

Haaura.g00005355

Gene Model ID

Haaura.CG.MTP2014.S490.g05355

Location

S490:29174..35539

Transcript Models and Sequences

  Haaura.CG.MTP2014.S490.g05355.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

9 results

IPR Term Analysis Definition
HATPase_C CDD Histidine kinase/HSP90-like ATPase
Mlh1_C Pfam DNA mismatch repair protein Mlh1, C-terminal
DNA_mismatch_repair_C Pfam DNA mismatch repair protein, C-terminal
Ribosomal_S5_D2-typ_fold SUPERFAMILY Ribosomal protein S5 domain 2-type fold
DNA_mismatch_repair_C SMART DNA mismatch repair protein, C-terminal
HATPase_C_sf Gene3D Histidine kinase/HSP90-like ATPase superfamily
DNA_mismatch_repair_MLH1 PANTHER DNA mismatch repair protein Mlh1
Ribosomal_S5_D2-typ_fold_subgr Gene3D Ribosomal protein S5 domain 2-type fold, subgroup
HATPase_C_sf SUPERFAMILY Histidine kinase/HSP90-like ATPase superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

45 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
nuclear-transcribed mRNA poly(A) tail shortening Hs biological process
resolution of meiotic recombination intermediates Hs biological process
condensed chromosome Hs cellular component
condensed nuclear chromosome Hs cellular component
synaptonemal complex Hs cellular component
male germ cell nucleus Hs cellular component
chromatin binding Hs molecular function
single-stranded DNA binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
chromosome Hs cellular component
chiasma Hs cellular component
late recombination nodule Hs cellular component
DNA repair Hs biological process
mismatch repair Hs biological process
double-strand break repair via nonhomologous end joining Hs biological process
cellular response to DNA damage stimulus Hs biological process
cell cycle Hs biological process
male meiosis chromosome segregation Hs biological process
synapsis Hs biological process
reciprocal meiotic recombination Hs biological process
male meiotic nuclear division Hs biological process
spermatogenesis Hs biological process
intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
membrane Hs cellular component
female meiosis chromosome segregation Hs biological process
somatic hypermutation of immunoglobulin genes Hs biological process
ATPase activity Hs molecular function
mismatched DNA binding Hs molecular function
guanine/thymine mispair binding Hs molecular function
mismatch repair complex Hs cellular component
MutLalpha complex Hs cellular component
MutSalpha complex binding Hs molecular function
meiotic metaphase I plate congression Hs biological process
meiotic chromosome segregation Hs biological process
meiotic telomere clustering Hs biological process
homologous chromosome segregation Hs biological process
isotype switching Hs biological process
negative regulation of mitotic recombination Hs biological process
oogenesis Hs biological process
meiotic spindle midzone assembly Hs biological process
meiotic cell cycle Hs biological process

GO (Blast)

30 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 599 0.0
condensed chromosome Hs cellular component 599 0.0
condensed nuclear chromosome Hs cellular component 599 0.0
synaptonemal complex Hs cellular component 599 0.0
male germ cell nucleus Hs cellular component 599 0.0
DNA binding Hs molecular function 130 1.14e-31
chromatin binding Hs molecular function 599 0.0
single-stranded DNA binding Hs molecular function 599 0.0
nuclease activity Hs molecular function 130 1.14e-31
endonuclease activity Hs molecular function 130 1.14e-31
protein binding Hs molecular function 599 0.0
ATP binding Hs molecular function 599 0.0
nucleus Hs cellular component 599 0.0
nucleoplasm Hs cellular component 599 0.0
chromosome Hs cellular component 599 0.0
chiasma Hs cellular component 599 0.0
late recombination nodule Hs cellular component 599 0.0
cytosol Hs cellular component 130 1.14e-31
plasma membrane Hs cellular component 130 1.14e-31
microtubule cytoskeleton Hs cellular component 130 1.14e-31
membrane Hs cellular component 599 0.0
hydrolase activity Hs molecular function 130 1.14e-31
ATPase activity Hs molecular function 599 0.0
mismatched DNA binding Hs molecular function 599 0.0
guanine/thymine mispair binding Hs molecular function 599 0.0
single base insertion or deletion binding Hs molecular function 130 1.14e-31
mismatch repair complex Hs cellular component 599 0.0
MutLalpha complex Hs cellular component 599 0.0
MutSalpha complex binding Hs molecular function 599 0.0
cytoplasmic ribonucleoprotein granule Hs cellular component 130 1.14e-31

GO (InterProScan)

4 results

GO Term Analysis Type e-value
ATP binding SMART molecular function 8.7E-49
mismatch repair PANTHER biological process 4.1E-192
mismatched DNA binding SMART molecular function 8.7E-49
mismatch repair complex PANTHER cellular component 4.1E-192

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