Gene Card
Best human hits
EARS2; EPRS; QARS
Species
Unique Gene ID
Haaura.g00005544
Gene Model ID
Haaura.CG.MTP2014.S521.g05544
Location
S521:32747..35114
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
10 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Glu/Gln-tRNA-synth | PRINTS | Glutamyl/glutaminyl-tRNA synthetase |
| aa-tRNA-synth_I_CS | ProSitePatterns | Aminoacyl-tRNA synthetase, class I, conserved site |
| Rbsml_L25/Gln-tRNA_synth_N | Gene3D | Ribosomal protein L25/Gln-tRNA synthetase, N-terminal |
| Gln-tRNA-synth_Ib_RNA-bd_2 | Pfam | Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 |
| Gln-tRNA-synth_Ib_RNA-bd_N | Pfam | Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal |
| Rossmann-like_a/b/a_fold | Gene3D | Rossmann-like alpha/beta/alpha sandwich fold |
| Glu/Gln-tRNA-synth_Ib_codon-bd | Pfam | Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain |
| Ribosomal_L25/Gln-tRNA_synth | SUPERFAMILY | Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily |
| Gln-tRNA-synth | TIGRFAM | Glutamine-tRNA synthetase |
| Glu/Gln-tRNA-synth_Ib_cat-dom | Pfam | Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
24 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| nucleotide binding | Hs | molecular function |
| aminoacyl-tRNA ligase activity | Hs | molecular function |
| glutamine-tRNA ligase activity | Hs | molecular function |
| protein kinase inhibitor activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| ATP binding | Hs | molecular function |
| cytoplasm | Hs | cellular component |
| mitochondrial matrix | Hs | cellular component |
| cytosol | Hs | cellular component |
| translation | Hs | biological process |
| tRNA aminoacylation for protein translation | Hs | biological process |
| glutaminyl-tRNA aminoacylation | Hs | biological process |
| negative regulation of protein kinase activity | Hs | biological process |
| brain development | Hs | biological process |
| membrane | Hs | cellular component |
| integral component of membrane | Hs | cellular component |
| ligase activity | Hs | molecular function |
| aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component |
| protein kinase binding | Hs | molecular function |
| negative regulation of stress-activated MAPK cascade | Hs | biological process |
| macromolecular complex | Hs | cellular component |
| tRNA aminoacylation | Hs | biological process |
| negative regulation of transcription, DNA-templated | Hs | biological process |
| negative regulation of apoptotic signaling pathway | Hs | biological process |
GO (Blast)
30 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| tRNA binding | Hs | molecular function | 58.9 | 7.75e-09 |
| nucleotide binding | Hs | molecular function | 1025 | 0.0 |
| RNA binding | Hs | molecular function | 239 | 3.21e-66 |
| catalytic activity | Hs | molecular function | 239 | 3.21e-66 |
| aminoacyl-tRNA ligase activity | Hs | molecular function | 1025 | 0.0 |
| glutamate-tRNA ligase activity | Hs | molecular function | 239 | 3.21e-66 |
| glutamine-tRNA ligase activity | Hs | molecular function | 1025 | 0.0 |
| proline-tRNA ligase activity | Hs | molecular function | 239 | 3.21e-66 |
| protein kinase inhibitor activity | Hs | molecular function | 1025 | 0.0 |
| protein binding | Hs | molecular function | 1025 | 0.0 |
| ATP binding | Hs | molecular function | 1025 | 0.0 |
| cytoplasm | Hs | cellular component | 1025 | 0.0 |
| mitochondrion | Hs | cellular component | 58.9 | 7.75e-09 |
| mitochondrial matrix | Hs | cellular component | 1025 | 0.0 |
| cytosol | Hs | cellular component | 1025 | 0.0 |
| zinc ion binding | Hs | molecular function | 239 | 3.21e-66 |
| membrane | Hs | cellular component | 1025 | 0.0 |
| integral component of membrane | Hs | cellular component | 1025 | 0.0 |
| ligase activity | Hs | molecular function | 1025 | 0.0 |
| aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component | 1025 | 0.0 |
| protein kinase binding | Hs | molecular function | 1025 | 0.0 |
| intracellular ribonucleoprotein complex | Hs | cellular component | 239 | 3.21e-66 |
| macromolecular complex | Hs | cellular component | 1025 | 0.0 |
| RNA stem-loop binding | Hs | molecular function | 239 | 3.21e-66 |
| identical protein binding | Hs | molecular function | 239 | 3.21e-66 |
| protein homodimerization activity | Hs | molecular function | 239 | 3.21e-66 |
| metal ion binding | Hs | molecular function | 239 | 3.21e-66 |
| glutamate-tRNA(Gln) ligase activity | Hs | molecular function | 58.9 | 7.75e-09 |
| GTPase binding | Hs | molecular function | 239 | 3.21e-66 |
| GAIT complex | Hs | cellular component | 239 | 3.21e-66 |
GO (InterProScan)
7 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| nucleotide binding | TIGRFAM | molecular function | 1.4E-180 |
| aminoacyl-tRNA ligase activity | Pfam | molecular function | 1.7E-110 |
| ATP binding | TIGRFAM | molecular function | 1.4E-180 |
| cytoplasm | TIGRFAM | cellular component | 1.4E-180 |
| translation | SUPERFAMILY | biological process | 8.37E-54 |
| glutaminyl-tRNA aminoacylation | TIGRFAM | biological process | 1.4E-180 |
| tRNA aminoacylation | Pfam | biological process | 1.7E-110 |
