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GENE CARD

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Gene Card

Best human hits

SESN1; SESN2; SESN3

Species

H.aurantium

Unique Gene ID

Haaura.g00001333

Gene Model ID

Haaura.CG.MTP2014.S55.g01333

Location

S55:39787..41635

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
Sestrin Pfam Sestrin
AhpD-like SUPERFAMILY AhpD-like
Sestrin PANTHER Sestrin

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

44 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
fibrillar center Hs cellular component
regulation of protein phosphorylation Hs biological process
GDP-dissociation inhibitor activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
cytosol Hs cellular component
fatty acid beta-oxidation Hs biological process
mitochondrion organization Hs biological process
response to glucose Hs biological process
positive regulation of macroautophagy Hs biological process
oxidoreductase activity Hs molecular function
oxidoreductase activity, acting on peroxide as acceptor Hs molecular function
negative regulation of cell growth Hs biological process
DNA damage response, signal transduction by p53 class mediator Hs biological process
nucleotide-activated protein kinase complex Hs cellular component
TORC2 complex Hs cellular component
mitochondrial DNA metabolic process Hs biological process
sulfiredoxin activity Hs molecular function
response to insulin Hs biological process
cellular response to amino acid starvation Hs biological process
cellular response to oxidative stress Hs biological process
TORC2 signaling Hs biological process
cellular response to glucose starvation Hs biological process
glucose homeostasis Hs biological process
protein kinase B signaling Hs biological process
glucose import Hs biological process
regulation of insulin receptor signaling pathway Hs biological process
regulation of protein kinase B signaling Hs biological process
peroxiredoxin activity Hs molecular function
oxidation-reduction process Hs biological process
GATOR2 complex Hs cellular component
triglyceride homeostasis Hs biological process
leucine binding Hs molecular function
cellular response to amino acid stimulus Hs biological process
reactive oxygen species metabolic process Hs biological process
cellular oxidant detoxification Hs biological process
positive regulation of protein localization to nucleus Hs biological process
regulation of response to reactive oxygen species Hs biological process
negative regulation of TORC1 signaling Hs biological process
cellular response to leucine starvation Hs biological process
ATG1/ULK1 kinase complex Hs cellular component
regulation of cAMP-dependent protein kinase activity Hs biological process

GO (Blast)

16 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
fibrillar center Hs cellular component 441 5.49e-149
GDP-dissociation inhibitor activity Hs molecular function 389 7.80e-130
protein binding Hs molecular function 441 5.49e-149
nucleus Hs cellular component 441 5.49e-149
cytoplasm Hs cellular component 441 5.49e-149
mitochondrion Hs cellular component 389 7.80e-130
cytosol Hs cellular component 441 5.49e-149
oxidoreductase activity Hs molecular function 441 5.49e-149
oxidoreductase activity, acting on peroxide as acceptor Hs molecular function 389 7.80e-130
nucleotide-activated protein kinase complex Hs cellular component 389 7.80e-130
TORC2 complex Hs cellular component 432 3.55e-146
sulfiredoxin activity Hs molecular function 389 7.80e-130
peroxiredoxin activity Hs molecular function 441 5.49e-149
GATOR2 complex Hs cellular component 441 5.49e-149
leucine binding Hs molecular function 441 5.49e-149
ATG1/ULK1 kinase complex Hs cellular component 389 7.80e-130

GO (InterProScan)

2 results

GO Term Analysis Type e-value
nucleus Pfam cellular component 2.1E-165
regulation of response to reactive oxygen species Pfam biological process 2.1E-165