Aniseed - Gene card

Gene Card

Best human hits

ARAF; BRAF; RAF1

Species

H.aurantium

Unique Gene ID

Haaura.g00001453

Gene Model ID

Haaura.CG.MTP2014.S61.g01453

Location

S61:114798..124131

Transcript Models and Sequences

Haaura.CG.MTP2014.S61.g01453.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

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Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term	Analysis	Definition
Prot_kinase_dom	SMART	Protein kinase domain
PE/DAG-bd	ProSiteProfiles	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
PE/DAG-bd	SMART	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
PE/DAG-bd	CDD	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Protein_kinase_ATP_BS	ProSitePatterns	Protein kinase, ATP binding site
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain
PE/DAG-bd	ProSitePatterns	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Ser-Thr/Tyr_kinase_cat_dom	Pfam	Serine-threonine/tyrosine-protein kinase, catalytic domain
PE/DAG-bd	Pfam	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily
Ser/Thr_kinase_AS	ProSitePatterns	Serine/threonine-protein kinase, active site
RBD_dom	Pfam	Raf-like Ras-binding
Ubiquitin-like_domsf	SUPERFAMILY	Ubiquitin-like domain superfamily

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

95 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
MAPK cascade	Hs	biological process
nucleotide binding	Hs	molecular function
activation of MAPKK activity	Hs	biological process
response to hypoxia	Hs	biological process
cellular glucose homeostasis	Hs	biological process
positive regulation of protein phosphorylation	Hs	biological process
protein kinase activity	Hs	molecular function
protein serine/threonine kinase activity	Hs	molecular function
MAP kinase kinase kinase activity	Hs	molecular function
signal transducer activity, downstream of receptor	Hs	molecular function
calcium ion binding	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
intracellular	Hs	cellular component
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
mitochondrial outer membrane	Hs	cellular component
Golgi apparatus	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
cellular protein modification process	Hs	biological process
protein phosphorylation	Hs	biological process
apoptotic process	Hs	biological process
signal transduction	Hs	biological process
activation of adenylate cyclase activity	Hs	biological process
multicellular organism development	Hs	biological process
heart development	Hs	biological process
adenylate cyclase binding	Hs	molecular function
cell proliferation	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
visual learning	Hs	biological process
animal organ morphogenesis	Hs	biological process
negative regulation of signal transduction	Hs	biological process
positive regulation of gene expression	Hs	biological process
adenylate cyclase activator activity	Hs	molecular function
membrane	Hs	cellular component
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
nuclear speck	Hs	cellular component
transferase activity	Hs	molecular function
Ras GTPase binding	Hs	molecular function
enzyme binding	Hs	molecular function
cell differentiation	Hs	biological process
platelet activation	Hs	biological process
thyroid gland development	Hs	biological process
pseudopodium	Hs	cellular component
negative regulation of protein complex assembly	Hs	biological process
mitogen-activated protein kinase kinase binding	Hs	molecular function
regulation of TOR signaling	Hs	biological process
regulation of proteasomal ubiquitin-dependent protein catabolic process	Hs	biological process
positive regulation of peptidyl-serine phosphorylation	Hs	biological process
ion transmembrane transport	Hs	biological process
somatic stem cell population maintenance	Hs	biological process
regulation of Rho protein signal transduction	Hs	biological process
intracellular signal transduction	Hs	biological process
wound healing	Hs	biological process
regulation of cell proliferation	Hs	biological process
identical protein binding	Hs	molecular function
regulation of apoptotic process	Hs	biological process
neuron projection	Hs	cellular component
negative regulation of apoptotic process	Hs	biological process
positive regulation of catalytic activity	Hs	biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Hs	biological process
intracellular membrane-bounded organelle	Hs	cellular component
positive T cell selection	Hs	biological process
response to peptide hormone	Hs	biological process
negative regulation of neuron apoptotic process	Hs	biological process
cell body	Hs	cellular component
intermediate filament cytoskeleton organization	Hs	biological process
regulation of T cell differentiation	Hs	biological process
regulation of cell differentiation	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
alpha-beta T cell differentiation	Hs	biological process
metal ion binding	Hs	molecular function
protein heterodimerization activity	Hs	molecular function
neurotrophin TRK receptor signaling pathway	Hs	biological process
thymus development	Hs	biological process
regulation of axon regeneration	Hs	biological process
positive regulation of axon regeneration	Hs	biological process
positive regulation of axonogenesis	Hs	biological process
T cell receptor signaling pathway	Hs	biological process
protein heterooligomerization	Hs	biological process
positive regulation of stress fiber assembly	Hs	biological process
response to cAMP	Hs	biological process
long-term synaptic potentiation	Hs	biological process
head morphogenesis	Hs	biological process
face development	Hs	biological process
positive regulation of ERK1 and ERK2 cascade	Hs	biological process
cellular response to calcium ion	Hs	biological process
establishment of protein localization to membrane	Hs	biological process
positive regulation of substrate adhesion-dependent cell spreading	Hs	biological process
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Hs	biological process
regulation of cell motility	Hs	biological process
negative regulation of synaptic vesicle exocytosis	Hs	biological process

GO (Blast)

32 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	596	0.0
protein kinase activity	Hs	molecular function	596	0.0
protein serine/threonine kinase activity	Hs	molecular function	596	0.0
MAP kinase kinase kinase activity	Hs	molecular function	596	0.0
signal transducer activity, downstream of receptor	Hs	molecular function	596	0.0
calcium ion binding	Hs	molecular function	596	0.0
protein binding	Hs	molecular function	596	0.0
ATP binding	Hs	molecular function	596	0.0
intracellular	Hs	cellular component	596	0.0
nucleus	Hs	cellular component	596	0.0
cytoplasm	Hs	cellular component	596	0.0
mitochondrion	Hs	cellular component	596	0.0
mitochondrial outer membrane	Hs	cellular component	435	5.16e-143
Golgi apparatus	Hs	cellular component	435	5.16e-143
cytosol	Hs	cellular component	596	0.0
plasma membrane	Hs	cellular component	596	0.0
adenylate cyclase binding	Hs	molecular function	435	5.16e-143
adenylate cyclase activator activity	Hs	molecular function	435	5.16e-143
membrane	Hs	cellular component	596	0.0
kinase activity	Hs	molecular function	596	0.0
nuclear speck	Hs	cellular component	435	5.16e-143
transferase activity	Hs	molecular function	596	0.0
Ras GTPase binding	Hs	molecular function	596	0.0
enzyme binding	Hs	molecular function	435	5.16e-143
pseudopodium	Hs	cellular component	435	5.16e-143
mitogen-activated protein kinase kinase binding	Hs	molecular function	596	0.0
identical protein binding	Hs	molecular function	596	0.0
neuron projection	Hs	cellular component	596	0.0
intracellular membrane-bounded organelle	Hs	cellular component	596	0.0
cell body	Hs	cellular component	596	0.0
metal ion binding	Hs	molecular function	596	0.0
protein heterodimerization activity	Hs	molecular function	596	0.0

GO (InterProScan)

6 results

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	6.1E-57
signal transducer activity, downstream of receptor	Pfam	molecular function	1.2E-7
ATP binding	SMART	molecular function	3.4E-55
protein phosphorylation	Pfam	biological process	6.1E-57
signal transduction	Pfam	biological process	1.2E-7
intracellular signal transduction	CDD	biological process	1.71276E-12