Gene Card
Best human hits
MAP2K1; MAP2K2; MAP2K5
Species
Unique Gene ID
Haaura.g00001839
Gene Model ID
Haaura.CG.MTP2014.S88.g01839
Location
S88:23859..26608
Transcript Models and Sequences
Haaura.CG.MTP2014.S88.g01839.01.t
Haaura.CG.MTP2014.S88.g01839.02.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
6 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
| Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
| Prot_kinase_dom | SMART | Protein kinase domain |
| Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
| Prot_kinase_dom | Pfam | Protein kinase domain |
| Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
66 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| MAPK cascade | Hs | biological process |
| nucleotide binding | Hs | molecular function |
| activation of MAPK activity | Hs | biological process |
| regulation of protein phosphorylation | Hs | biological process |
| protein kinase activity | Hs | molecular function |
| protein serine/threonine kinase activity | Hs | molecular function |
| MAP kinase kinase activity | Hs | molecular function |
| protein serine/threonine/tyrosine kinase activity | Hs | molecular function |
| protein tyrosine kinase activity | Hs | molecular function |
| signal transducer, downstream of receptor, with protein tyrosine phosphatase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| ATP binding | Hs | molecular function |
| extracellular region | Hs | cellular component |
| nucleus | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| mitochondrion | Hs | cellular component |
| early endosome | Hs | cellular component |
| late endosome | Hs | cellular component |
| peroxisomal membrane | Hs | cellular component |
| endoplasmic reticulum | Hs | cellular component |
| Golgi apparatus | Hs | cellular component |
| microtubule organizing center | Hs | cellular component |
| cytosol | Hs | cellular component |
| cytoskeleton | Hs | cellular component |
| microtubule | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| cell-cell junction | Hs | cellular component |
| focal adhesion | Hs | cellular component |
| protein phosphorylation | Hs | biological process |
| chemotaxis | Hs | biological process |
| cell cycle arrest | Hs | biological process |
| signal transduction | Hs | biological process |
| regulation of mitotic cell cycle | Hs | biological process |
| heart development | Hs | biological process |
| protein C-terminus binding | Hs | molecular function |
| negative regulation of cell proliferation | Hs | biological process |
| cytoplasmic side of plasma membrane | Hs | cellular component |
| positive regulation of gene expression | Hs | biological process |
| negative regulation of gene expression | Hs | biological process |
| membrane | Hs | cellular component |
| kinase activity | Hs | molecular function |
| phosphorylation | Hs | biological process |
| transferase activity | Hs | molecular function |
| peptidyl-threonine phosphorylation | Hs | biological process |
| peptidyl-tyrosine phosphorylation | Hs | biological process |
| PDZ domain binding | Hs | molecular function |
| neuron differentiation | Hs | biological process |
| keratinocyte differentiation | Hs | biological process |
| thyroid gland development | Hs | biological process |
| regulation of apoptotic process | Hs | biological process |
| protein serine/threonine kinase activator activity | Hs | molecular function |
| positive regulation of cell differentiation | Hs | biological process |
| positive regulation of transcription, DNA-templated | Hs | biological process |
| metal ion binding | Hs | molecular function |
| protein N-terminus binding | Hs | molecular function |
| perinuclear region of cytoplasm | Hs | cellular component |
| thymus development | Hs | biological process |
| regulation of axon regeneration | Hs | biological process |
| cell motility | Hs | biological process |
| positive regulation of axonogenesis | Hs | biological process |
| face development | Hs | biological process |
| extracellular exosome | Hs | cellular component |
| positive regulation of ERK1 and ERK2 cascade | Hs | biological process |
| positive regulation of protein serine/threonine kinase activity | Hs | biological process |
| cellular senescence | Hs | biological process |
| scaffold protein binding | Hs | molecular function |
GO (Blast)
38 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 506 | 5.89e-180 |
| protein kinase activity | Hs | molecular function | 506 | 5.89e-180 |
| protein serine/threonine kinase activity | Hs | molecular function | 506 | 5.89e-180 |
| MAP kinase kinase activity | Hs | molecular function | 506 | 5.89e-180 |
| protein serine/threonine/tyrosine kinase activity | Hs | molecular function | 506 | 5.89e-180 |
| protein tyrosine kinase activity | Hs | molecular function | 506 | 5.89e-180 |
| signal transducer, downstream of receptor, with protein tyrosine phosphatase activity | Hs | molecular function | 506 | 5.89e-180 |
| protein binding | Hs | molecular function | 506 | 5.89e-180 |
| ATP binding | Hs | molecular function | 506 | 5.89e-180 |
| extracellular region | Hs | cellular component | 489 | 2.36e-173 |
| nucleus | Hs | cellular component | 506 | 5.89e-180 |
| cytoplasm | Hs | cellular component | 506 | 5.89e-180 |
| mitochondrion | Hs | cellular component | 506 | 5.89e-180 |
| early endosome | Hs | cellular component | 506 | 5.89e-180 |
| late endosome | Hs | cellular component | 506 | 5.89e-180 |
| peroxisomal membrane | Hs | cellular component | 489 | 2.36e-173 |
| endoplasmic reticulum | Hs | cellular component | 506 | 5.89e-180 |
| Golgi apparatus | Hs | cellular component | 506 | 5.89e-180 |
| microtubule organizing center | Hs | cellular component | 506 | 5.89e-180 |
| spindle | Hs | cellular component | 251 | 1.80e-79 |
| cytosol | Hs | cellular component | 506 | 5.89e-180 |
| cytoskeleton | Hs | cellular component | 506 | 5.89e-180 |
| microtubule | Hs | cellular component | 489 | 2.36e-173 |
| plasma membrane | Hs | cellular component | 506 | 5.89e-180 |
| cell-cell junction | Hs | cellular component | 489 | 2.36e-173 |
| focal adhesion | Hs | cellular component | 506 | 5.89e-180 |
| protein C-terminus binding | Hs | molecular function | 506 | 5.89e-180 |
| cytoplasmic side of plasma membrane | Hs | cellular component | 489 | 2.36e-173 |
| membrane | Hs | cellular component | 506 | 5.89e-180 |
| kinase activity | Hs | molecular function | 506 | 5.89e-180 |
| transferase activity | Hs | molecular function | 506 | 5.89e-180 |
| PDZ domain binding | Hs | molecular function | 489 | 2.36e-173 |
| protein serine/threonine kinase activator activity | Hs | molecular function | 506 | 5.89e-180 |
| metal ion binding | Hs | molecular function | 489 | 2.36e-173 |
| protein N-terminus binding | Hs | molecular function | 506 | 5.89e-180 |
| perinuclear region of cytoplasm | Hs | cellular component | 489 | 2.36e-173 |
| extracellular exosome | Hs | cellular component | 506 | 5.89e-180 |
| scaffold protein binding | Hs | molecular function | 506 | 5.89e-180 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein kinase activity | Pfam | molecular function | 2.9E-22 |
| ATP binding | Pfam | molecular function | 2.9E-22 |
| protein phosphorylation | Pfam | biological process | 2.9E-22 |
