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GENE CARD

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Gene Card

Best human hits

CASP2; CASP3; CASP7

Species

H.roretzi

Unique Gene ID

Harore.g00007320

Gene Model ID

Harore.CG.MTP2014.S130.g07320

Location

S130:49079..51790

Transcript Models and Sequences

  Harore.CG.MTP2014.S130.g07320.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
Pept_C14_p10 ProSiteProfiles Peptidase C14, caspase non-catalytic subunit p10
Caspase_cys_AS ProSitePatterns Peptidase family C14A, cysteine active site
Pept_C14A SMART Peptidase C14A, caspase catalytic domain
Caspase_2 PANTHER Caspase-2
CARD ProSiteProfiles CARD domain
Pept_C14_p20 ProSiteProfiles Peptidase C14, p20 domain
DEATH-like_dom_sf SUPERFAMILY Death-like domain superfamily
CARD Pfam CARD domain
CARD SMART CARD domain
Pept_C14A PRINTS Peptidase C14A, caspase catalytic domain
Caspase_his_AS ProSitePatterns Peptidase family C14A, His active site
Pept_C14A CDD Peptidase C14A, caspase catalytic domain
Caspase-like_dom_sf SUPERFAMILY Caspase-like domain superfamily

GOSlim

44 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Blast cellular component
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
cytosol Orthology cellular component
plasma membrane Blast cellular component
proteolysis Orthology biological process
apoptotic process Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
brain development Orthology biological process
peptidase activity Orthology molecular function
membrane Orthology cellular component
hydrolase activity Orthology molecular function
enzyme binding Orthology molecular function
intracellular signal transduction Orthology biological process
identical protein binding Orthology molecular function
regulation of apoptotic process Orthology biological process
positive regulation of apoptotic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
intracellular membrane-bounded organelle Blast cellular component
membrane raft Blast cellular component
animal organ development Orthology biological process
endopeptidase activity Orthology molecular function
positive regulation of hydrolase activity Orthology biological process
developmental process Orthology biological process
peptidase activity, acting on L-amino acid peptides Orthology molecular function
gene expression Orthology biological process
reproductive process Orthology biological process
cell development Orthology biological process
programmed cell death Orthology biological process
signal transduction Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cell projection assembly Orthology biological process
positive regulation of signal transduction Orthology biological process
cell cycle Blast biological process
enzyme regulator activity Blast molecular function
protein kinase binding Blast molecular function
molecular transducer activity Blast molecular function
protein serine/threonine kinase activity Blast molecular function
receptor binding Blast molecular function
enzyme activator activity Blast molecular function
plasma membrane part Blast cellular component
macromolecular complex Blast cellular component

GO (Orthology)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
neural retina development Hs biological process
cysteine-type endopeptidase activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
cytosol Hs cellular component
proteolysis Hs biological process
apoptotic process Hs biological process
activation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
brain development Hs biological process
aging Hs biological process
peptidase activity Hs molecular function
cysteine-type peptidase activity Hs molecular function
intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
membrane Hs cellular component
protein processing Hs biological process
hydrolase activity Hs molecular function
enzyme binding Hs molecular function
protein domain specific binding Hs molecular function
ectopic germ cell programmed cell death Hs biological process
identical protein binding Hs molecular function
regulation of apoptotic process Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
positive regulation of neuron apoptotic process Hs biological process
cellular response to mechanical stimulus Hs biological process
cysteine-type endopeptidase activity involved in apoptotic process Hs molecular function
apoptotic signaling pathway Hs biological process
extrinsic apoptotic signaling pathway in absence of ligand Hs biological process
execution phase of apoptosis Hs biological process
cysteine-type endopeptidase activity involved in execution phase of apoptosis Hs molecular function
positive regulation of apoptotic signaling pathway Hs biological process

GO (Blast)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
protease binding Hs molecular function 139 1.03e-37
aspartic-type endopeptidase activity Hs molecular function 139 1.03e-37
cysteine-type endopeptidase activity Hs molecular function 244 4.05e-75
cyclin-dependent protein serine/threonine kinase inhibitor activity Hs molecular function 139 1.03e-37
death receptor binding Hs molecular function 139 1.03e-37
protein binding Hs molecular function 244 4.05e-75
nucleus Hs cellular component 244 4.05e-75
nucleoplasm Hs cellular component 139 1.03e-37
cytoplasm Hs cellular component 244 4.05e-75
mitochondrion Hs cellular component 244 4.05e-75
cytosol Hs cellular component 244 4.05e-75
plasma membrane Hs cellular component 139 1.03e-37
peptidase activity Hs molecular function 244 4.05e-75
cysteine-type peptidase activity Hs molecular function 244 4.05e-75
cysteine-type endopeptidase activator activity involved in apoptotic process Hs molecular function 139 1.03e-37
phospholipase A2 activator activity Hs molecular function 139 1.03e-37
membrane Hs cellular component 244 4.05e-75
hydrolase activity Hs molecular function 244 4.05e-75
enzyme binding Hs molecular function 244 4.05e-75
protein domain specific binding Hs molecular function 244 4.05e-75
death-inducing signaling complex Hs cellular component 139 1.03e-37
identical protein binding Hs molecular function 244 4.05e-75
intracellular membrane-bounded organelle Hs cellular component 137 8.60e-36
membrane raft Hs cellular component 139 1.03e-37
cysteine-type endopeptidase activity involved in apoptotic process Hs molecular function 244 4.05e-75
cysteine-type endopeptidase activity involved in execution phase of apoptosis Hs molecular function 244 4.05e-75

GO (InterProScan)

5 results

GO Term Analysis Type e-value
cysteine-type endopeptidase activity ProSiteProfiles molecular function 31.193
proteolysis ProSiteProfiles biological process 31.193
cysteine-type peptidase activity SMART molecular function 1.2E-76
regulation of apoptotic process SMART biological process 5.9E-13
cysteine-type endopeptidase activity involved in execution phase of apoptosis PANTHER molecular function 3.4E-99