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GENE CARD

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Gene Card

Best human hits

DNA2

Species

H.roretzi

Unique Gene ID

Harore.g00011755

Gene Model ID

Harore.CG.MTP2014.S1454.g11755

Location

S1454:0..3199

Transcript Models and Sequences

  Harore.CG.MTP2014.S1454.g11755.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

2 results

IPR Term Analysis Definition
Dna2 PANTHER Dna2
DNA_replication_fac_Dna2_N Pfam DNA replication factor Dna2, N-terminal

GOSlim

25 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
DNA binding Orthology molecular function
catalytic activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
mitochondrion Orthology cellular component
DNA replication Orthology biological process
DNA repair Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
metabolic process Orthology biological process
hydrolase activity Orthology molecular function
metal ion binding Orthology molecular function
cell cycle Orthology biological process
DNA metabolic process Orthology biological process
organelle organization Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
nucleoside-triphosphatase activity Orthology molecular function
mitochondrial matrix Orthology cellular component
macromolecular complex Orthology cellular component
RNA catabolic process Orthology biological process
RNA biosynthetic process Orthology biological process
cofactor binding Orthology molecular function

GO (Orthology)

42 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
DNA replication checkpoint Hs biological process
nucleotide binding Hs molecular function
telomere maintenance Hs biological process
DNA double-strand break processing Hs biological process
DNA synthesis involved in DNA repair Hs biological process
strand displacement Hs biological process
nuclear chromosome, telomeric region Hs cellular component
DNA binding Hs molecular function
DNA helicase activity Hs molecular function
catalytic activity Hs molecular function
helicase activity Hs molecular function
nuclease activity Hs molecular function
endonuclease activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
mitochondrion Hs cellular component
gamma DNA polymerase complex Hs cellular component
DNA replication Hs biological process
mitochondrial DNA replication Hs biological process
DNA repair Hs biological process
base-excision repair Hs biological process
cellular response to DNA damage stimulus Hs biological process
metabolic process Hs biological process
hydrolase activity Hs molecular function
ATPase activity Hs molecular function
site-specific endodeoxyribonuclease activity, specific for altered base Hs molecular function
5'-flap endonuclease activity Hs molecular function
DNA duplex unwinding Hs biological process
DNA replication, Okazaki fragment processing Hs biological process
mitochondrial nucleoid Hs cellular component
DNA replication, removal of RNA primer Hs biological process
5'-3' DNA helicase activity Hs molecular function
single-stranded DNA-dependent ATPase activity Hs molecular function
mitochondrial DNA repair Hs biological process
G-quadruplex DNA unwinding Hs biological process
positive regulation of DNA replication Hs biological process
metal ion binding Hs molecular function
iron-sulfur cluster binding Hs molecular function
4 iron, 4 sulfur cluster binding Hs molecular function
nucleic acid phosphodiester bond hydrolysis Hs biological process

GO (Blast)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 89.0 2.27e-18
nuclear chromosome, telomeric region Hs cellular component 89.0 2.27e-18
DNA binding Hs molecular function 89.0 2.27e-18
DNA helicase activity Hs molecular function 89.0 2.27e-18
catalytic activity Hs molecular function 89.0 2.27e-18
helicase activity Hs molecular function 89.0 2.27e-18
nuclease activity Hs molecular function 89.0 2.27e-18
endonuclease activity Hs molecular function 89.0 2.27e-18
protein binding Hs molecular function 89.0 2.27e-18
ATP binding Hs molecular function 89.0 2.27e-18
nucleus Hs cellular component 89.0 2.27e-18
nucleoplasm Hs cellular component 89.0 2.27e-18
mitochondrion Hs cellular component 89.0 2.27e-18
gamma DNA polymerase complex Hs cellular component 89.0 2.27e-18
hydrolase activity Hs molecular function 89.0 2.27e-18
ATPase activity Hs molecular function 89.0 2.27e-18
site-specific endodeoxyribonuclease activity, specific for altered base Hs molecular function 89.0 2.27e-18
5'-flap endonuclease activity Hs molecular function 89.0 2.27e-18
mitochondrial nucleoid Hs cellular component 89.0 2.27e-18
5'-3' DNA helicase activity Hs molecular function 89.0 2.27e-18
single-stranded DNA-dependent ATPase activity Hs molecular function 89.0 2.27e-18
metal ion binding Hs molecular function 89.0 2.27e-18
iron-sulfur cluster binding Hs molecular function 89.0 2.27e-18
4 iron, 4 sulfur cluster binding Hs molecular function 89.0 2.27e-18

GO (InterProScan)

3 results

GO Term Analysis Type e-value
5'-flap endonuclease activity PANTHER molecular function 2.3E-15
DNA replication, Okazaki fragment processing PANTHER biological process 2.3E-15
single-stranded DNA-dependent ATPase activity PANTHER molecular function 2.3E-15