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GENE CARD

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Gene Card

Best human hits

ILKAP; PPM1L; TAB1

Species

H.roretzi

Unique Gene ID

Harore.g00009874

Gene Model ID

Harore.CG.MTP2014.S156.g09874

Location

S156:196974..202213

Transcript Models and Sequences

  Harore.CG.MTP2014.S156.g09874.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
PPM-type_dom_sf Gene3D PPM-type phosphatase domain superfamily
PPM-type_phosphatase_dom SMART PPM-type phosphatase domain
PPM-type_phosphatase_dom Pfam PPM-type phosphatase domain
PP2C PANTHER Protein phosphatase 2C family
PPM-type_phosphatase_dom CDD PPM-type phosphatase domain
PPM-type_dom_sf SUPERFAMILY PPM-type phosphatase domain superfamily
PPM-type_phosphatase_dom ProSiteProfiles PPM-type phosphatase domain

GOSlim

41 results

GO Term Annotation Origin Type
catalytic activity Orthology molecular function
protein binding Orthology molecular function
nucleus Blast cellular component
nucleoplasm Blast cellular component
cytoplasm Blast cellular component
endoplasmic reticulum membrane Blast cellular component
cytosol Orthology cellular component
protein dephosphorylation Orthology biological process
enzyme activator activity Orthology molecular function
membrane Blast cellular component
integral component of membrane Blast cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
nuclear speck Orthology cellular component
hydrolase activity Orthology molecular function
cation binding Blast molecular function
metal ion binding Blast molecular function
extracellular exosome Blast cellular component
positive regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
signal transduction Orthology biological process
innate immune response Orthology biological process
anatomical structure morphogenesis Orthology biological process
heart development Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
cellular response to stress Orthology biological process
protein phosphorylation Orthology biological process
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
endosome Orthology cellular component
bounding membrane of organelle Orthology cellular component
peptidase activity, acting on L-amino acid peptides Orthology molecular function
animal organ development Orthology biological process
blood vessel development Orthology biological process
immune response Orthology biological process
protein kinase binding Orthology molecular function
cytokine-mediated signaling pathway Orthology biological process

GO (Orthology)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
activation of MAPKKK activity Hs biological process
activation of MAPK activity Hs biological process
MyD88-dependent toll-like receptor signaling pathway Hs biological process
heart morphogenesis Hs biological process
catalytic activity Hs molecular function
protein serine/threonine phosphatase activity Hs molecular function
protein binding Hs molecular function
cytosol Hs cellular component
protein dephosphorylation Hs biological process
transforming growth factor beta receptor signaling pathway Hs biological process
I-kappaB kinase/NF-kappaB signaling Hs biological process
JNK cascade Hs biological process
enzyme activator activity Hs molecular function
endosome membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
protein deubiquitination Hs biological process
nuclear speck Hs cellular component
kinase activator activity Hs molecular function
lung development Hs biological process
aorta development Hs biological process
Fc-epsilon receptor signaling pathway Hs biological process
positive regulation of MAP kinase activity Hs biological process
mitogen-activated protein kinase p38 binding Hs molecular function
positive regulation of NF-kappaB transcription factor activity Hs biological process
coronary vasculature development Hs biological process
interleukin-1-mediated signaling pathway Hs biological process

GO (Blast)

21 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
catalytic activity Hs molecular function 354 3.90e-116
phosphoprotein phosphatase activity Hs molecular function 73.6 7.36e-14
protein serine/threonine phosphatase activity Hs molecular function 354 3.90e-116
protein binding Hs molecular function 354 3.90e-116
nucleus Hs cellular component 73.6 7.36e-14
nucleoplasm Hs cellular component 73.6 7.36e-14
cytoplasm Hs cellular component 73.6 7.36e-14
endoplasmic reticulum membrane Hs cellular component 68.9 1.83e-12
cytosol Hs cellular component 354 3.90e-116
enzyme activator activity Hs molecular function 354 3.90e-116
endosome membrane Hs cellular component 354 3.90e-116
membrane Hs cellular component 68.9 1.83e-12
integral component of membrane Hs cellular component 68.9 1.83e-12
kinase activity Hs molecular function 354 3.90e-116
nuclear speck Hs cellular component 354 3.90e-116
hydrolase activity Hs molecular function 73.6 7.36e-14
kinase activator activity Hs molecular function 354 3.90e-116
cation binding Hs molecular function 73.6 7.36e-14
metal ion binding Hs molecular function 73.6 7.36e-14
mitogen-activated protein kinase p38 binding Hs molecular function 354 3.90e-116
extracellular exosome Hs cellular component 68.9 1.83e-12

GO (InterProScan)

3 results

GO Term Analysis Type e-value
catalytic activity CDD molecular function 3.08378E-45
protein serine/threonine phosphatase activity PANTHER molecular function 1.3E-115
protein dephosphorylation PANTHER biological process 1.3E-115