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GENE CARD

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Gene Card

Best human hits

ADAMTS1; ADAMTS15; ADAMTS5

Species

H.roretzi

Unique Gene ID

Harore.g00012833

Gene Model ID

Harore.CG.MTP2014.S233.g12833

Location

S233:46357..55008

Transcript Models and Sequences

  Harore.CG.MTP2014.S233.g12833.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

10 results

IPR Term Analysis Definition
Peptidase_M12B ProSiteProfiles Peptidase M12B, ADAM/reprolysin
TSP1_rpt ProSiteProfiles Thrombospondin type-1 (TSP1) repeat
TSP1_rpt SMART Thrombospondin type-1 (TSP1) repeat
TSP1_rpt_sf Gene3D Thrombospondin type-1 (TSP1) repeat superfamily
Peptidase_M12B Pfam Peptidase M12B, ADAM/reprolysin
MetalloPept_cat_dom_sf Gene3D Metallopeptidase, catalytic domain superfamily
TSP1_rpt Pfam Thrombospondin type-1 (TSP1) repeat
ADAM_spacer1 Pfam ADAM-TS Spacer 1
ADAM_Cys-rich SMART ADAM, cysteine-rich
TSP1_rpt_sf SUPERFAMILY Thrombospondin type-1 (TSP1) repeat superfamily

GOSlim

34 results

GO Term Annotation Origin Type
endopeptidase activity Orthology molecular function
metalloendopeptidase activity Orthology molecular function
integrin binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
endoplasmic reticulum lumen Orthology cellular component
proteolysis Orthology biological process
peptidase activity Orthology molecular function
metallopeptidase activity Orthology molecular function
zinc ion binding Orthology molecular function
negative regulation of cell proliferation Orthology biological process
cell surface Orthology cellular component
membrane Orthology cellular component
integral component of membrane Orthology cellular component
hydrolase activity Orthology molecular function
cytoplasmic vesicle Orthology cellular component
metal ion binding Orthology molecular function
nuclear speck Orthology cellular component
animal organ development Orthology biological process
extracellular region part Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
anion binding Orthology molecular function
carbohydrate derivative binding Orthology molecular function
cellular protein modification process Orthology biological process
response to bacterium Orthology biological process
defense response Orthology biological process
binding Orthology molecular function
anatomical structure formation involved in morphogenesis Orthology biological process
heart development Orthology biological process
system development Orthology biological process
enzyme binding Orthology molecular function
ion transport Orthology biological process
transmembrane transport Orthology biological process

GO (Orthology)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
kidney development Hs biological process
endopeptidase activity Hs molecular function
metalloendopeptidase activity Hs molecular function
integrin binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
proteinaceous extracellular matrix Hs cellular component
basement membrane Hs cellular component
extracellular space Hs cellular component
endoplasmic reticulum lumen Hs cellular component
proteolysis Hs biological process
integrin-mediated signaling pathway Hs biological process
heparin binding Hs molecular function
peptidase activity Hs molecular function
metallopeptidase activity Hs molecular function
zinc ion binding Hs molecular function
negative regulation of cell proliferation Hs biological process
cell surface Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
hydrolase activity Hs molecular function
cytoplasmic vesicle Hs cellular component
protein O-linked fucosylation Hs biological process
defense response to bacterium Hs biological process
metal ion binding Hs molecular function
extracellular matrix binding Hs molecular function
heart trabecula formation Hs biological process
skeletal system development Hs biological process
protease binding Hs molecular function
low-affinity phosphate transmembrane transporter activity Hs molecular function
nuclear speck Hs cellular component
extracellular matrix Hs cellular component
phosphate ion transmembrane transport Hs biological process

GO (Blast)

20 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
endopeptidase activity Hs molecular function 484 5.49e-159
metalloendopeptidase activity Hs molecular function 484 5.49e-159
integrin binding Hs molecular function 425 1.52e-136
protein binding Hs molecular function 425 1.52e-136
extracellular region Hs cellular component 484 5.49e-159
proteinaceous extracellular matrix Hs cellular component 484 5.49e-159
basement membrane Hs cellular component 459 6.09e-149
extracellular space Hs cellular component 484 5.49e-159
endoplasmic reticulum lumen Hs cellular component 425 1.52e-136
heparin binding Hs molecular function 484 5.49e-159
peptidase activity Hs molecular function 484 5.49e-159
metallopeptidase activity Hs molecular function 484 5.49e-159
zinc ion binding Hs molecular function 484 5.49e-159
cell surface Hs cellular component 484 5.49e-159
membrane Hs cellular component 459 6.09e-149
integral component of membrane Hs cellular component 459 6.09e-149
hydrolase activity Hs molecular function 484 5.49e-159
cytoplasmic vesicle Hs cellular component 459 6.09e-149
metal ion binding Hs molecular function 484 5.49e-159
extracellular matrix binding Hs molecular function 484 5.49e-159

GO (InterProScan)

3 results

GO Term Analysis Type e-value
metalloendopeptidase activity Pfam molecular function 2.8E-12
proteolysis Pfam biological process 2.8E-12
metallopeptidase activity Gene3D molecular function 5.4E-37

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