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GENE CARD

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  1. EST 'AV877118'

Gene Card

Best human hits

RARA; RARB; RARG

Species

H.roretzi

Unique Gene ID

Harore.g00003857

Gene Model ID

Harore.CG.MTP2014.S237.g03857

Location

S237:58475..65783

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Nucl_hrmn_rcpt_lig-bd Pfam Nuclear hormone receptor, ligand-binding domain
Retinoic_acid_rcpt PRINTS Retinoic acid receptor
Znf_hrmn_rcpt ProSitePatterns Zinc finger, nuclear hormone receptor-type
Nucl_hrmn_rcpt_lig-bd SMART Nuclear hormone receptor, ligand-binding domain
Znf_hrmn_rcpt ProSiteProfiles Zinc finger, nuclear hormone receptor-type
Nuclear_hrmn_rcpt PRINTS Nuclear hormone receptor
NHR_like_dom_sf SUPERFAMILY Nuclear hormone receptor-like domain superfamily
Znf_hrmn_rcpt SMART Zinc finger, nuclear hormone receptor-type
Znf_NHR/GATA Gene3D Zinc finger, NHR/GATA-type
Znf_hrmn_rcpt PRINTS Zinc finger, nuclear hormone receptor-type
Znf_hrmn_rcpt Pfam Zinc finger, nuclear hormone receptor-type

GOSlim

88 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
RNA polymerase II regulatory region DNA binding Orthology molecular function
DNA binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription coactivator activity Orthology molecular function
transcription corepressor activity Orthology molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
transcription initiation from RNA polymerase II promoter Orthology biological process
protein phosphorylation Orthology biological process
signal transduction Orthology biological process
spermatogenesis Orthology biological process
transcription factor binding Orthology molecular function
zinc ion binding Orthology molecular function
positive regulation of cell proliferation Orthology biological process
negative regulation of cell proliferation Orthology biological process
cell surface Orthology cellular component
regulation of gene expression Orthology biological process
positive regulation of gene expression Orthology biological process
negative regulation of gene expression Orthology biological process
integral component of membrane Orthology cellular component
enzyme binding Orthology molecular function
neurogenesis Orthology biological process
response to cytokine Orthology biological process
regulation of apoptotic process Orthology biological process
neuron projection Orthology cellular component
neuronal cell body Orthology cellular component
positive regulation of apoptotic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
positive regulation of programmed cell death Orthology biological process
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
protein heterodimerization activity Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
nucleic acid binding Orthology molecular function
animal organ development Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
nervous system development Orthology biological process
small molecule binding Orthology molecular function
anion binding Orthology molecular function
cell development Orthology biological process
response to lipid Orthology biological process
signaling receptor activity Orthology molecular function
cellular response to organic substance Orthology biological process
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
gamete generation Orthology biological process
binding Orthology molecular function
cellular component organization Orthology biological process
reproductive process Orthology biological process
multicellular organism development Orthology biological process
cytoskeleton Orthology cellular component
chromatin binding Orthology molecular function
anatomical structure morphogenesis Orthology biological process
developmental process Orthology biological process
protein kinase binding Orthology molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
response to organic substance Orthology biological process
cell differentiation Orthology biological process
immune system process Orthology biological process
neuron differentiation Orthology biological process
cell cycle Orthology biological process
translational initiation Orthology biological process
RNA binding Orthology molecular function
chemical synaptic transmission Orthology biological process
regulation of signaling Orthology biological process
system development Orthology biological process
cytoskeletal protein binding Orthology molecular function
heart development Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
head development Orthology biological process
anatomical structure development Orthology biological process
response to lipopolysaccharide Orthology biological process

GO (Orthology)

106 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
nuclear chromatin Hs cellular component
translation repressor activity, nucleic acid binding Hs molecular function
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
RNA polymerase II regulatory region DNA binding Hs molecular function
ureteric bud development Hs biological process
neural tube closure Hs biological process
liver development Hs biological process
retinoic acid binding Hs molecular function
chondrocyte development Hs biological process
retinal pigment epithelium development Hs biological process
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
steroid hormone receptor activity Hs molecular function
retinoic acid receptor activity Hs molecular function
transcription coactivator activity Hs molecular function
transcription corepressor activity Hs molecular function
nuclear receptor activity Hs molecular function
receptor binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription initiation from RNA polymerase II promoter Hs biological process
protein phosphorylation Hs biological process
signal transduction Hs biological process
germ cell development Hs biological process
spermatogenesis Hs biological process
transcription factor binding Hs molecular function
drug binding Hs molecular function
zinc ion binding Hs molecular function
positive regulation of cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
regulation of cell size Hs biological process
male gonad development Hs biological process
anterior/posterior pattern specification Hs biological process
cell surface Hs cellular component
regulation of gene expression Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
actin cytoskeleton Hs cellular component
integral component of membrane Hs cellular component
negative regulation of translation Hs biological process
enzyme binding Hs molecular function
protein domain specific binding Hs molecular function
neurogenesis Hs biological process
dendrite Hs cellular component
embryonic camera-type eye development Hs biological process
chromatin DNA binding Hs molecular function
regulation of myelination Hs biological process
response to estradiol Hs biological process
response to retinoic acid Hs biological process
response to cytokine Hs biological process
embryonic hindlimb morphogenesis Hs biological process
multicellular organism growth Hs biological process
histone deacetylase binding Hs molecular function
regulation of apoptotic process Hs biological process
neuron projection Hs cellular component
camera-type eye development Hs biological process
neuronal cell body Hs cellular component
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
positive regulation of programmed cell death Hs biological process
apoptotic cell clearance Hs biological process
steroid hormone mediated signaling pathway Hs biological process
protein kinase B binding Hs molecular function
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
retinoic acid-responsive element binding Hs molecular function
response to ethanol Hs biological process
negative regulation of cell differentiation Hs biological process
regulation of myeloid cell differentiation Hs biological process
positive regulation of neuron differentiation Hs biological process
positive regulation of cell cycle Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
negative regulation of translational initiation Hs biological process
metal ion binding Hs molecular function
retinoid X receptor binding Hs molecular function
protein heterodimerization activity Hs molecular function
mRNA 5'-UTR binding Hs molecular function
embryonic eye morphogenesis Hs biological process
regulation of synaptic plasticity Hs biological process
retinoic acid receptor signaling pathway Hs biological process
perinuclear region of cytoplasm Hs cellular component
embryonic digestive tract development Hs biological process
reproductive structure development Hs biological process
protein kinase A binding Hs molecular function
alpha-actinin binding Hs molecular function
ventricular cardiac muscle cell differentiation Hs biological process
retina development in camera-type eye Hs biological process
canonical Wnt signaling pathway Hs biological process
limb development Hs biological process
face development Hs biological process
bone development Hs biological process
bone morphogenesis Hs biological process
epithelium development Hs biological process
cellular response to lipopolysaccharide Hs biological process
cellular response to retinoic acid Hs biological process
cellular response to estrogen stimulus Hs biological process

GO (Blast)

44 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nuclear chromatin Hs cellular component 439 7.53e-151
translation repressor activity, nucleic acid binding Hs molecular function 439 7.53e-151
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 453 9.89e-157
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 453 9.89e-157
RNA polymerase II regulatory region DNA binding Hs molecular function 439 7.53e-151
retinoic acid binding Hs molecular function 439 7.53e-151
DNA binding Hs molecular function 453 9.89e-157
transcription factor activity, sequence-specific DNA binding Hs molecular function 453 9.89e-157
steroid hormone receptor activity Hs molecular function 453 9.89e-157
retinoic acid receptor activity Hs molecular function 453 9.89e-157
transcription coactivator activity Hs molecular function 439 7.53e-151
transcription corepressor activity Hs molecular function 439 7.53e-151
nuclear receptor activity Hs molecular function 439 7.53e-151
receptor binding Hs molecular function 439 7.53e-151
protein binding Hs molecular function 439 7.53e-151
nucleus Hs cellular component 453 9.89e-157
nucleoplasm Hs cellular component 453 9.89e-157
transcription factor complex Hs cellular component 427 1.27e-146
cytoplasm Hs cellular component 453 9.89e-157
cytosol Hs cellular component 439 7.53e-151
transcription factor binding Hs molecular function 439 7.53e-151
drug binding Hs molecular function 453 9.89e-157
zinc ion binding Hs molecular function 453 9.89e-157
cell surface Hs cellular component 439 7.53e-151
actin cytoskeleton Hs cellular component 439 7.53e-151
integral component of membrane Hs cellular component 427 1.27e-146
enzyme binding Hs molecular function 439 7.53e-151
protein domain specific binding Hs molecular function 439 7.53e-151
dendrite Hs cellular component 439 7.53e-151
chromatin DNA binding Hs molecular function 439 7.53e-151
histone deacetylase binding Hs molecular function 439 7.53e-151
neuron projection Hs cellular component 439 7.53e-151
neuronal cell body Hs cellular component 439 7.53e-151
protein kinase B binding Hs molecular function 439 7.53e-151
sequence-specific DNA binding Hs molecular function 453 9.89e-157
transcription regulatory region DNA binding Hs molecular function 439 7.53e-151
retinoic acid-responsive element binding Hs molecular function 439 7.53e-151
metal ion binding Hs molecular function 453 9.89e-157
retinoid X receptor binding Hs molecular function 453 9.89e-157
protein heterodimerization activity Hs molecular function 439 7.53e-151
mRNA 5'-UTR binding Hs molecular function 439 7.53e-151
perinuclear region of cytoplasm Hs cellular component 439 7.53e-151
protein kinase A binding Hs molecular function 439 7.53e-151
alpha-actinin binding Hs molecular function 439 7.53e-151

GO (InterProScan)

10 results

GO Term Analysis Type e-value
DNA binding PRINTS molecular function 3.1E-28
transcription factor activity, sequence-specific DNA binding SMART molecular function 1.3E-39
steroid hormone receptor activity PRINTS molecular function 5.1E-28
retinoic acid receptor activity PRINTS molecular function 3.1E-28
nucleus SMART cellular component 1.3E-39
regulation of transcription, DNA-templated SMART biological process 1.3E-39
zinc ion binding SMART molecular function 1.3E-39
steroid hormone mediated signaling pathway SMART biological process 3.7E-33
sequence-specific DNA binding SMART molecular function 1.3E-39
retinoic acid receptor signaling pathway PRINTS biological process 3.1E-28