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Gene Card

Best human hits

SLIT1; SLIT2; SLIT3

Species

H.roretzi

Unique Gene ID

Harore.g00006829

Gene Model ID

Harore.CG.MTP2014.S248.g06829

Location

S248:5174..77446

Transcript Models and Sequences

  Harore.CG.MTP2014.S248.g06829.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

22 results

IPR Term Analysis Definition
EGF-like_CS ProSitePatterns EGF-like, conserved site
EGF-like_dom ProSiteProfiles EGF-like domain
EGF-like_CS Pfam EGF-like, conserved site
ConA-like_dom_sf SUPERFAMILY Concanavalin A-like lectin/glucanase domain superfamily
Leu-rich_rpt ProSiteProfiles Leucine-rich repeat
LRR_dom_sf Gene3D Leucine-rich repeat domain superfamily
EGF-like_dom SMART EGF-like domain
Leu-rich_rpt Pfam Leucine-rich repeat
Cys-rich_flank_reg_C Pfam Cysteine-rich flanking region, C-terminal
EGF-type_Asp/Asn_hydroxyl_site ProSitePatterns EGF-type aspartate/asparagine hydroxylation site
EGF-like_dom Pfam EGF-like domain
Laminin_G SMART Laminin G domain
EGF_Ca-bd_CS ProSitePatterns EGF-like calcium-binding, conserved site
Laminin_G Pfam Laminin G domain
Cys-rich_flank_reg_C SMART Cysteine-rich flanking region, C-terminal
Laminin_G ProSiteProfiles Laminin G domain
EGF-like_Ca-bd_dom SMART EGF-like calcium-binding domain
Leu-rich_rpt_typical-subtyp SMART Leucine-rich repeat, typical subtype
LRR_5 Pfam Leucine rich repeat 5
LRRNT Pfam Leucine-rich repeat N-terminal domain
LRRNT SMART Leucine-rich repeat N-terminal domain
Cys_knot_C ProSiteProfiles Cystine knot, C-terminal

GOSlim

43 results

GO Term Annotation Origin Type
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
intracellular Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
plasma membrane Orthology cellular component
chemotaxis Orthology biological process
multicellular organism development Orthology biological process
nervous system development Orthology biological process
axonogenesis Orthology biological process
axon guidance Orthology biological process
negative regulation of cell proliferation Orthology biological process
negative regulation of gene expression Orthology biological process
membrane Orthology cellular component
cell differentiation Orthology biological process
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
positive regulation of apoptotic process Orthology biological process
neuron projection morphogenesis Orthology biological process
extracellular exosome Orthology cellular component
animal organ development Orthology biological process
protein phosphorylation Orthology biological process
cell migration Orthology biological process
angiogenesis Orthology biological process
regulation of GTPase activity Orthology biological process
GTPase regulator activity Orthology molecular function
intracellular transport Orthology biological process
anion binding Orthology molecular function
carbohydrate derivative binding Orthology molecular function
anatomical structure morphogenesis Orthology biological process
cell projection assembly Orthology biological process
brain development Orthology biological process
cellular component organization Orthology biological process
organelle organization Orthology biological process
cellular response to organic substance Orthology biological process
cell surface receptor signaling pathway Orthology biological process
receptor binding Orthology molecular function
small GTPase mediated signal transduction Orthology biological process
negative regulation of signal transduction Orthology biological process
response to lipid Orthology biological process
immune system process Orthology biological process

GO (Orthology)

55 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
ureteric bud development Hs biological process
negative regulation of protein phosphorylation Hs biological process
cell migration involved in sprouting angiogenesis Hs biological process
GTPase inhibitor activity Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
intracellular Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
plasma membrane Hs cellular component
chemotaxis Hs biological process
nuclear migration Hs biological process
multicellular organism development Hs biological process
nervous system development Hs biological process
axonogenesis Hs biological process
axon guidance Hs biological process
motor neuron axon guidance Hs biological process
heparin binding Hs molecular function
negative regulation of cell proliferation Hs biological process
animal organ morphogenesis Hs biological process
negative regulation of lamellipodium assembly Hs biological process
negative regulation of gene expression Hs biological process
membrane Hs cellular component
olfactory bulb development Hs biological process
telencephalon cell migration Hs biological process
cell differentiation Hs biological process
negative regulation of cell growth Hs biological process
negative regulation of cell migration Hs biological process
negative regulation of actin filament polymerization Hs biological process
retinal ganglion cell axon guidance Hs biological process
cellular response to hormone stimulus Hs biological process
dorsal/ventral axon guidance Hs biological process
negative regulation of GTPase activity Hs biological process
Roundabout signaling pathway Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
positive regulation of apoptotic process Hs biological process
negative regulation of vascular permeability Hs biological process
laminin-1 binding Hs molecular function
proteoglycan binding Hs molecular function
Roundabout binding Hs molecular function
branching morphogenesis of an epithelial tube Hs biological process
neuron projection morphogenesis Hs biological process
axon extension involved in axon guidance Hs biological process
forebrain morphogenesis Hs biological process
positive regulation of axonogenesis Hs biological process
negative chemotaxis Hs biological process
induction of negative chemotaxis Hs biological process
negative regulation of small GTPase mediated signal transduction Hs biological process
response to cortisol Hs biological process
negative regulation of synapse assembly Hs biological process
extracellular exosome Hs cellular component
negative regulation of neutrophil chemotaxis Hs biological process

GO (Blast)

17 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
GTPase inhibitor activity Hs molecular function 1216 0.0
calcium ion binding Hs molecular function 1216 0.0
protein binding Hs molecular function 1216 0.0
extracellular region Hs cellular component 1216 0.0
extracellular space Hs cellular component 1216 0.0
intracellular Hs cellular component 1184 0.0
cytoplasm Hs cellular component 1216 0.0
mitochondrion Hs cellular component 1196 0.0
plasma membrane Hs cellular component 1216 0.0
heparin binding Hs molecular function 1216 0.0
membrane Hs cellular component 1216 0.0
identical protein binding Hs molecular function 1216 0.0
protein homodimerization activity Hs molecular function 1216 0.0
laminin-1 binding Hs molecular function 1216 0.0
proteoglycan binding Hs molecular function 1216 0.0
Roundabout binding Hs molecular function 1216 0.0
extracellular exosome Hs cellular component 1216 0.0

GO (InterProScan)

2 results

GO Term Analysis Type e-value
calcium ion binding SMART molecular function 5.9E-10
protein binding Pfam molecular function 1.4E-12

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