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GENE CARD

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Gene Card

Best human hits

PFKFB1; PFKFB3; PFKFB4

Species

H.roretzi

Unique Gene ID

Harore.g00001094

Gene Model ID

Harore.CG.MTP2014.S267.g01094

Location

S267:35659..41923

Transcript Models and Sequences

  Harore.CG.MTP2014.S267.g01094.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

10 results

IPR Term Analysis Definition
His_Pase_superF_clade-1 SMART Histidine phosphatase superfamily, clade-1
His_PPase_superfam Gene3D Histidine phosphatase superfamily
6Phosfructo_kin Pfam 6-phosphofructo-2-kinase
His_PPase_superfam SUPERFAMILY Histidine phosphatase superfamily
His_Pase_superF_clade-1 Pfam Histidine phosphatase superfamily, clade-1
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase
6Pfruct_kin PRINTS Fructose-2,6-bisphosphatase
PG/BPGM_mutase_AS ProSitePatterns Phosphoglycerate/bisphosphoglycerate mutase, active site
His_Pase_superF_clade-1 CDD Histidine phosphatase superfamily, clade-1
6Pfruct_kin PANTHER Fructose-2,6-bisphosphatase

GOSlim

34 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
catalytic activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
nucleoplasm Orthology cellular component
cytosol Orthology cellular component
brain development Orthology biological process
metabolic process Orthology biological process
kinase activity Orthology molecular function
phosphorylation Orthology biological process
dephosphorylation Orthology biological process
transferase activity Orthology molecular function
hydrolase activity Orthology molecular function
kinase binding Orthology molecular function
identical protein binding Orthology molecular function
nucleus Orthology cellular component
cytoplasm Orthology cellular component
protein kinase binding Orthology molecular function
phosphotransferase activity, alcohol group as acceptor Orthology molecular function
organic substance metabolic process Orthology biological process
phosphate-containing compound metabolic process Orthology biological process
nucleobase-containing compound metabolic process Orthology biological process
oxidation-reduction process Orthology biological process
animal organ development Orthology biological process
response to organic substance Orthology biological process
positive regulation of catalytic activity Orthology biological process
response to stress Orthology biological process
macromolecular complex Orthology cellular component
response to lipid Orthology biological process
anion binding Orthology molecular function
carbohydrate derivative binding Orthology molecular function
cellular metabolic process Orthology biological process
protein transport Orthology biological process
cell-cell signaling Orthology biological process

GO (Orthology)

37 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
catalytic activity Hs molecular function
6-phosphofructo-2-kinase activity Hs molecular function
fructose-2,6-bisphosphate 2-phosphatase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleoplasm Hs cellular component
cytosol Hs cellular component
fructose metabolic process Hs biological process
fructose 2,6-bisphosphate metabolic process Hs biological process
gluconeogenesis Hs biological process
glycolytic process Hs biological process
brain development Hs biological process
metabolic process Hs biological process
kinase activity Hs molecular function
phosphorylation Hs biological process
dephosphorylation Hs biological process
transferase activity Hs molecular function
hydrolase activity Hs molecular function
kinase binding Hs molecular function
animal organ regeneration Hs biological process
response to insulin Hs biological process
positive regulation of glucokinase activity Hs biological process
response to starvation Hs biological process
identical protein binding Hs molecular function
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex Hs cellular component
carbohydrate phosphorylation Hs biological process
response to glucocorticoid Hs biological process
response to cAMP Hs biological process
fructose-6-phosphate binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
glucose catabolic process Hs biological process
pyruvate metabolic process Hs biological process
response to glucose Hs biological process
protein kinase binding Hs molecular function
positive regulation of insulin secretion Hs biological process

GO (Blast)

15 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 581 0.0
catalytic activity Hs molecular function 581 0.0
6-phosphofructo-2-kinase activity Hs molecular function 581 0.0
fructose-2,6-bisphosphate 2-phosphatase activity Hs molecular function 581 0.0
protein binding Hs molecular function 581 0.0
ATP binding Hs molecular function 581 0.0
nucleoplasm Hs cellular component 572 0.0
cytosol Hs cellular component 581 0.0
kinase activity Hs molecular function 581 0.0
transferase activity Hs molecular function 581 0.0
hydrolase activity Hs molecular function 581 0.0
kinase binding Hs molecular function 581 0.0
identical protein binding Hs molecular function 581 0.0
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex Hs cellular component 581 0.0
fructose-6-phosphate binding Hs molecular function 581 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
catalytic activity PANTHER molecular function 6.5E-213
6-phosphofructo-2-kinase activity Pfam molecular function 6.2E-90
ATP binding PANTHER molecular function 6.5E-213
fructose metabolic process Pfam biological process 6.2E-90
fructose 2,6-bisphosphate metabolic process PANTHER biological process 6.5E-213
metabolic process ProSitePatterns biological process

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