Gene Card
Best human hits
HERC1; HERC2
Species
Unique Gene ID
Harore.g00013162
Gene Model ID
Harore.CG.MTP2014.S277.g13162
Location
S277:65707..100394
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Mib_Herc2 | ProSiteProfiles | Mib-herc2 |
Znf_ZZ | ProSitePatterns | Zinc finger, ZZ-type |
Reg_chr_condens | ProSitePatterns | Regulator of chromosome condensation, RCC1 |
Znf_ZZ | Pfam | Zinc finger, ZZ-type |
Reg_chr_condens | ProSiteProfiles | Regulator of chromosome condensation, RCC1 |
Mib_Herc2_sf | Gene3D | Mib/herc2 domain superfamily |
CPH_domain | Pfam | CPH domain |
Beta-propeller_rpt_TECPR | SMART | Beta-propeller repeat TECPR |
Mib_Herc2_sf | SUPERFAMILY | Mib/herc2 domain superfamily |
Rib_L2_dom2 | Gene3D | Ribosomal protein L2, domain 2 |
Isochorismatase-like_sf | Gene3D | Isochorismatase-like superfamily |
RCC1/BLIP-II | SUPERFAMILY | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II |
Cyt_B5-like_heme/steroid_sf | SUPERFAMILY | Cytochrome b5-like heme/steroid binding domain superfamily |
APC_su10/DOC_dom | ProSiteProfiles | APC10/DOC domain |
Galactose-bd-like_sf | SUPERFAMILY | Galactose-binding-like domain superfamily |
RCC1/BLIP-II | Gene3D | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II |
Multihaem_cyt | ProSiteProfiles | Multihaem cytochrome |
APC_su10/DOC_dom | SMART | APC10/DOC domain |
Reg_chr_condens | Pfam | Regulator of chromosome condensation, RCC1 |
Mib_Herc2 | Pfam | Mib-herc2 |
Reg_chr_condens | PRINTS | Regulator of chromosome condensation, RCC1 |
Cyt_B5-like_heme/steroid_sf | Gene3D | Cytochrome b5-like heme/steroid binding domain superfamily |
Isochorismatase-like_sf | SUPERFAMILY | Isochorismatase-like superfamily |
Isochorismatase-like | Pfam | Isochorismatase-like |
Znf_ZZ | ProSiteProfiles | Zinc finger, ZZ-type |
Znf_ZZ | SMART | Zinc finger, ZZ-type |
Galactose-bd-like_sf | Gene3D | Galactose-binding-like domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
ubiquitin-protein transferase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrial inner membrane | Orthology | cellular component |
Golgi apparatus | Blast | cellular component |
cytosol | Blast | cellular component |
cytoskeleton | Orthology | cellular component |
DNA repair | Orthology | biological process |
intracellular protein transport | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
spermatogenesis | Orthology | biological process |
zinc ion binding | Orthology | molecular function |
membrane | Orthology | cellular component |
protein ubiquitination | Orthology | biological process |
transferase activity | Orthology | molecular function |
ubiquitin protein ligase binding | Orthology | molecular function |
metal ion binding | Orthology | molecular function |
regulation of molecular function | Orthology | biological process |
catalytic activity | InterProScan | molecular function |
metabolic process | InterProScan | biological process |
enzyme binding | Orthology | molecular function |
molecular function regulator | Orthology | molecular function |
cytoplasmic part | Orthology | cellular component |
microtubule organizing center | Orthology | cellular component |
proteolysis | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
ubiquitin-protein transferase activity | Hs | molecular function |
guanyl-nucleotide exchange factor activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
mitochondrial inner membrane | Hs | cellular component |
centriole | Hs | cellular component |
cytoskeleton | Hs | cellular component |
DNA repair | Hs | biological process |
double-strand break repair via nonhomologous end joining | Hs | biological process |
intracellular protein transport | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
spermatogenesis | Hs | biological process |
zinc ion binding | Hs | molecular function |
membrane | Hs | cellular component |
protein ubiquitination | Hs | biological process |
transferase activity | Hs | molecular function |
ubiquitin protein ligase binding | Hs | molecular function |
SUMO binding | Hs | molecular function |
proteasome-mediated ubiquitin-dependent protein catabolic process | Hs | biological process |
metal ion binding | Hs | molecular function |
ubiquitin protein ligase activity | Hs | molecular function |
regulation of molecular function | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ubiquitin-protein transferase activity | Hs | molecular function | 1865 | 0.0 |
guanyl-nucleotide exchange factor activity | Hs | molecular function | 1865 | 0.0 |
ARF guanyl-nucleotide exchange factor activity | Hs | molecular function | 370 | 5.67e-102 |
protein binding | Hs | molecular function | 1865 | 0.0 |
nucleus | Hs | cellular component | 1865 | 0.0 |
nucleoplasm | Hs | cellular component | 1865 | 0.0 |
cytoplasm | Hs | cellular component | 1865 | 0.0 |
mitochondrial inner membrane | Hs | cellular component | 1865 | 0.0 |
Golgi apparatus | Hs | cellular component | 370 | 5.67e-102 |
centriole | Hs | cellular component | 1865 | 0.0 |
cytosol | Hs | cellular component | 370 | 5.67e-102 |
cytoskeleton | Hs | cellular component | 1865 | 0.0 |
zinc ion binding | Hs | molecular function | 1865 | 0.0 |
membrane | Hs | cellular component | 1865 | 0.0 |
transferase activity | Hs | molecular function | 1865 | 0.0 |
ubiquitin protein ligase binding | Hs | molecular function | 1865 | 0.0 |
SUMO binding | Hs | molecular function | 1865 | 0.0 |
metal ion binding | Hs | molecular function | 1865 | 0.0 |
ubiquitin protein ligase activity | Hs | molecular function | 1865 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ubiquitin-protein transferase activity | Gene3D | molecular function | 3.1E-25 |
zinc ion binding | SMART | molecular function | 8.2E-8 |
protein ubiquitination | Pfam | biological process | 5.1E-19 |
metal ion binding | Gene3D | molecular function | 3.1E-25 |
catalytic activity | Gene3D | molecular function | 5.5E-65 |
metabolic process | Gene3D | biological process | 5.5E-65 |