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GENE CARD

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Gene Card

Best human hits

NAE1; SAE1; UBA1

Species

H.roretzi

Unique Gene ID

Harore.g00012180

Gene Model ID

Harore.CG.MTP2014.S334.g12180

Location

S334:91087..98872

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
Ubiquitin-activating_enz SUPERFAMILY Ubiquitin-activating enzyme
APP-BP1 PANTHER NEDD8-activating enzyme E1 regulatory subunit APP-BP1
ThiF_NAD_FAD-bd Pfam THIF-type NAD/FAD binding fold
APP-BP1 PIRSF NEDD8-activating enzyme E1 regulatory subunit APP-BP1

GOSlim

36 results

GO Term Annotation Origin Type
nucleotide binding Blast molecular function
RNA binding Blast molecular function
protein binding Orthology molecular function
ATP binding Blast molecular function
nucleus Blast cellular component
nucleoplasm Blast cellular component
cytoplasm Orthology cellular component
mitochondrion Blast cellular component
lysosomal membrane Blast cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
cellular protein modification process Orthology biological process
apoptotic process Orthology biological process
cell cycle Orthology biological process
signal transduction Orthology biological process
protein C-terminus binding Blast molecular function
enzyme activator activity Blast molecular function
membrane Orthology cellular component
protein ubiquitination Blast biological process
ligase activity Orthology molecular function
ubiquitin protein ligase binding Orthology molecular function
regulation of apoptotic process Orthology biological process
protein heterodimerization activity Orthology molecular function
extracellular exosome Blast cellular component
G2/M transition of mitotic cell cycle Orthology biological process
protein modification by small protein conjugation Orthology biological process
intracellular organelle part Blast cellular component
intracellular non-membrane-bounded organelle Blast cellular component
whole membrane Blast cellular component
endosome Blast cellular component
bounding membrane of organelle Blast cellular component
anchoring junction Blast cellular component
endoplasmic reticulum membrane Blast cellular component
nuclear part Blast cellular component
macromolecular complex Blast cellular component
enzyme binding Blast molecular function

GO (Orthology)

18 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
protein binding Hs molecular function
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
apoptotic process Hs biological process
cell cycle Hs biological process
signal transduction Hs biological process
ubiquitin-like modifier activating enzyme activity Hs molecular function
membrane Hs cellular component
NEDD8 activating enzyme activity Hs molecular function
ubiquitin protein ligase binding Hs molecular function
mitotic DNA replication checkpoint Hs biological process
regulation of apoptotic process Hs biological process
regulation of neuron apoptotic process Hs biological process
post-translational protein modification Hs biological process
protein neddylation Hs biological process
protein heterodimerization activity Hs molecular function
neuron apoptotic process Hs biological process

GO (Blast)

30 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 63.5 2.06e-10
heterochromatin Hs cellular component 63.5 2.06e-10
RNA binding Hs molecular function 63.5 2.06e-10
ubiquitin activating enzyme activity Hs molecular function 95.5 1.77e-21
protein binding Hs molecular function 540 0.0
ATP binding Hs molecular function 63.5 2.06e-10
nucleus Hs cellular component 95.5 1.77e-21
nucleoplasm Hs cellular component 95.5 1.77e-21
cytoplasm Hs cellular component 540 0.0
mitochondrion Hs cellular component 63.5 2.06e-10
lysosomal membrane Hs cellular component 63.5 2.06e-10
cytosol Hs cellular component 540 0.0
plasma membrane Hs cellular component 540 0.0
protein C-terminus binding Hs molecular function 95.5 1.77e-21
enzyme activator activity Hs molecular function 95.5 1.77e-21
ubiquitin-like modifier activating enzyme activity Hs molecular function 540 0.0
endosome membrane Hs cellular component 63.5 2.06e-10
membrane Hs cellular component 540 0.0
ligase activity Hs molecular function 95.5 1.77e-21
acid-amino acid ligase activity Hs molecular function 63.5 2.06e-10
NEDD8 activating enzyme activity Hs molecular function 540 0.0
SUMO activating enzyme activity Hs molecular function 95.5 1.77e-21
desmosome Hs cellular component 63.5 2.06e-10
rough endoplasmic reticulum membrane Hs cellular component 63.5 2.06e-10
SUMO activating enzyme complex Hs cellular component 95.5 1.77e-21
ubiquitin protein ligase binding Hs molecular function 540 0.0
ATP-dependent protein binding Hs molecular function 95.5 1.77e-21
small protein activating enzyme binding Hs molecular function 95.5 1.77e-21
protein heterodimerization activity Hs molecular function 540 0.0
extracellular exosome Hs cellular component 63.5 2.06e-10

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ubiquitin-like modifier activating enzyme activity SUPERFAMILY molecular function 1.22E-120
NEDD8 activating enzyme activity PIRSF molecular function 1.7E-169
protein neddylation PIRSF biological process 1.7E-169