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GENE CARD

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Gene Card

Best human hits

ITGB1; ITGB2; ITGB3

Species

H.roretzi

Unique Gene ID

Harore.g00010299

Gene Model ID

Harore.CG.MTP2014.S44.g10299

Location

S44:334274..342184

Transcript Models and Sequences

  Harore.CG.MTP2014.S44.g10299.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
vWFA_dom_sf Gene3D von Willebrand factor A-like domain superfamily
Integrin_bsu_tail_dom_sf SUPERFAMILY Integrin beta tail domain superfamily
Integrin_bsu PRINTS Integrin beta subunit
Integrin_bsu_cyt_dom Pfam Integrin beta subunit, cytoplasmic domain
Integrin_bsu PANTHER Integrin beta subunit
Integrin_bsu_VWA SMART Integrin beta subunit, VWA domain
Integrin_bsu ProSitePatterns Integrin beta subunit
Integrin_bsu_VWA Pfam Integrin beta subunit, VWA domain
Integrin_bsu PIRSF Integrin beta subunit
Integrin_dom_sf SUPERFAMILY Integrin domain superfamily
vWFA_dom_sf SUPERFAMILY von Willebrand factor A-like domain superfamily
Integrin_bsu_tail SMART Integrin beta subunit, tail

GOSlim

94 results

GO Term Annotation Origin Type
G1/S transition of mitotic cell cycle Orthology biological process
actin binding Orthology molecular function
integrin binding Orthology molecular function
protein binding Orthology molecular function
nucleus Blast cellular component
cytoplasm Orthology cellular component
endosome Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
focal adhesion Orthology cellular component
apoptotic process Orthology biological process
cell adhesion Orthology biological process
cell-cell signaling Orthology biological process
positive regulation of cell proliferation Orthology biological process
cell surface Orthology cellular component
membrane Orthology cellular component
integral component of membrane Orthology cellular component
cell migration Orthology biological process
cytokine-mediated signaling pathway Orthology biological process
enzyme binding Orthology molecular function
protein kinase binding Orthology molecular function
lamellipodium Orthology cellular component
cell junction Orthology cellular component
extracellular matrix organization Orthology biological process
neuron projection development Orthology biological process
cytoplasmic vesicle Orthology cellular component
melanosome Orthology cellular component
identical protein binding Blast molecular function
cell projection Orthology cellular component
positive regulation of apoptotic process Orthology biological process
positive regulation of GTPase activity Orthology biological process
macromolecular complex binding Orthology molecular function
membrane raft Orthology cellular component
synapse Orthology cellular component
metal ion binding Orthology molecular function
protein heterodimerization activity Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
cell adhesion molecule binding Orthology molecular function
extracellular exosome Orthology cellular component
synaptic membrane Orthology cellular component
extracellular vesicle Orthology cellular component
binding Orthology molecular function
cell differentiation Orthology biological process
plasma membrane region Orthology cellular component
cell leading edge Orthology cellular component
angiogenesis Orthology biological process
immune system process Orthology biological process
defense response Orthology biological process
membrane organization Orthology biological process
organelle organization Orthology biological process
cell surface receptor signaling pathway Orthology biological process
developmental process Orthology biological process
macromolecular complex Orthology cellular component
gamete generation Orthology biological process
cell morphogenesis Orthology biological process
nervous system process Orthology biological process
plasma membrane part Orthology cellular component
signaling receptor activity Orthology molecular function
brain development Orthology biological process
cell morphogenesis involved in differentiation Orthology biological process
cytoskeletal part Orthology cellular component
animal organ development Orthology biological process
transmembrane signaling receptor activity Orthology molecular function
chemotaxis Orthology biological process
cell projection membrane Orthology cellular component
signal transduction Orthology biological process
innate immune response Orthology biological process
small GTPase mediated signal transduction Orthology biological process
negative regulation of signal transduction Orthology biological process
whole membrane Orthology cellular component
intracellular organelle part Orthology cellular component
endomembrane system Orthology cellular component
bounding membrane of organelle Orthology cellular component
myelin sheath Orthology cellular component
anatomical structure formation involved in morphogenesis Orthology biological process
multicellular organism development Orthology biological process
protein localization to membrane Orthology biological process
postsynapse Orthology cellular component
cell development Orthology biological process
axonogenesis Orthology biological process
heart development Orthology biological process
cell morphogenesis involved in neuron differentiation Orthology biological process
neuron projection morphogenesis Orthology biological process
regulation of cellular metabolic process Orthology biological process
protein phosphorylation Orthology biological process
immune response Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
cell cycle Orthology biological process
intracellular signal transduction Orthology biological process
positive regulation of signal transduction Orthology biological process
cytoplasmic part Orthology cellular component
regulation of signal transduction Orthology biological process
catalytic activity Blast molecular function
receptor binding Blast molecular function

GO (Orthology)

128 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
G1/S transition of mitotic cell cycle Hs biological process
amyloid-beta binding Hs molecular function
virus receptor activity Hs molecular function
cell fate specification Hs biological process
ruffle Hs cellular component
complement component C3b binding Hs molecular function
fibronectin binding Hs molecular function
protease binding Hs molecular function
cell migration involved in sprouting angiogenesis Hs biological process
leukocyte migration involved in inflammatory response Hs biological process
actin binding Hs molecular function
receptor activity Hs molecular function
integrin binding Hs molecular function
protein binding Hs molecular function
cytoplasm Hs cellular component
endosome Hs cellular component
plasma membrane Hs cellular component
focal adhesion Hs cellular component
phagocytosis Hs biological process
phagocytosis, engulfment Hs biological process
apoptotic process Hs biological process
inflammatory response Hs biological process
cellular defense response Hs biological process
cell adhesion Hs biological process
homophilic cell adhesion via plasma membrane adhesion molecules Hs biological process
cell-matrix adhesion Hs biological process
integrin-mediated signaling pathway Hs biological process
cell-cell signaling Hs biological process
aging Hs biological process
positive regulation of cell proliferation Hs biological process
integrin complex Hs cellular component
germ cell migration Hs biological process
regulation of cell shape Hs biological process
visual learning Hs biological process
external side of plasma membrane Hs cellular component
cell surface Hs cellular component
intercalated disc Hs cellular component
coreceptor activity Hs molecular function
membrane Hs cellular component
integral component of membrane Hs cellular component
viral process Hs biological process
cell migration Hs biological process
cytokine-mediated signaling pathway Hs biological process
protein kinase binding Hs molecular function
C-X3-C chemokine binding Hs molecular function
formation of radial glial scaffolds Hs biological process
lamellipodium Hs cellular component
cell junction Hs cellular component
filopodium Hs cellular component
B cell differentiation Hs biological process
extracellular matrix organization Hs biological process
ICAM-3 receptor activity Hs molecular function
neutrophil chemotaxis Hs biological process
heat shock protein binding Hs molecular function
neuron projection development Hs biological process
cytoplasmic vesicle Hs cellular component
cell-substrate adhesion Hs biological process
neuromuscular junction Hs cellular component
receptor internalization Hs biological process
cleavage furrow Hs cellular component
ruffle membrane Hs cellular component
cell adhesion mediated by integrin Hs biological process
cell-cell adhesion mediated by integrin Hs biological process
toll-like receptor 4 signaling pathway Hs biological process
substrate adhesion-dependent cell spreading Hs biological process
integrin alpha1-beta1 complex Hs cellular component
integrin alpha2-beta1 complex Hs cellular component
integrin alpha3-beta1 complex Hs cellular component
integrin alpha7-beta1 complex Hs cellular component
integrin alpha8-beta1 complex Hs cellular component
integrin alpha10-beta1 complex Hs cellular component
integrin alpha11-beta1 complex Hs cellular component
integrin alphaL-beta2 complex Hs cellular component
integrin alphaM-beta2 complex Hs cellular component
negative regulation of Rho protein signal transduction Hs biological process
specific granule membrane Hs cellular component
myelin sheath abaxonal region Hs cellular component
endodermal cell differentiation Hs biological process
sarcolemma Hs cellular component
melanosome Hs cellular component
cell projection Hs cellular component
positive regulation of apoptotic process Hs biological process
receptor clustering Hs biological process
dendritic spine Hs cellular component
receptor complex Hs cellular component
laminin binding Hs molecular function
endothelial cell migration Hs biological process
positive regulation of GTPase activity Hs biological process
plasma membrane raft Hs cellular component
macromolecular complex binding Hs molecular function
membrane raft Hs cellular component
synapse Hs cellular component
sarcomere organization Hs biological process
cadherin binding Hs molecular function
positive regulation of nitric oxide biosynthetic process Hs biological process
negative regulation of cell differentiation Hs biological process
positive regulation of angiogenesis Hs biological process
viral entry into host cell Hs biological process
metal ion binding Hs molecular function
protein heterodimerization activity Hs molecular function
mesodermal cell differentiation Hs biological process
perinuclear region of cytoplasm Hs cellular component
axon extension Hs biological process
cardiac muscle tissue development Hs biological process
dendrite morphogenesis Hs biological process
regulation of peptidyl-tyrosine phosphorylation Hs biological process
regulation of immune response Hs biological process
cell adhesion molecule binding Hs molecular function
leukocyte migration Hs biological process
positive regulation of NF-kappaB transcription factor activity Hs biological process
regulation of cell cycle Hs biological process
positive regulation of protein kinase B signaling Hs biological process
cardiac muscle cell differentiation Hs biological process
recycling endosome Hs cellular component
extracellular exosome Hs cellular component
tertiary granule membrane Hs cellular component
invadopodium membrane Hs cellular component
basement membrane organization Hs biological process
synaptic membrane Hs cellular component
cell-cell adhesion Hs biological process
collagen binding involved in cell-matrix adhesion Hs molecular function
cytoplasmic region Hs cellular component
ficolin-1-rich granule membrane Hs cellular component
positive regulation of protein localization to plasma membrane Hs biological process
extracellular vesicle Hs cellular component
neutrophil migration Hs biological process
positive regulation of receptor activity Hs biological process
integrin alpha4-beta7 complex Hs cellular component

GO (Blast)

87 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
amyloid-beta binding Hs molecular function 495 1.12e-163
virus receptor activity Hs molecular function 530 1.07e-176
ruffle Hs cellular component 530 1.07e-176
complement component C3b binding Hs molecular function 495 1.12e-163
fibronectin binding Hs molecular function 530 1.07e-176
protease binding Hs molecular function 530 1.07e-176
protein disulfide isomerase activity Hs molecular function 494 6.80e-163
actin binding Hs molecular function 530 1.07e-176
receptor activity Hs molecular function 530 1.07e-176
platelet-derived growth factor receptor binding Hs molecular function 494 6.80e-163
integrin binding Hs molecular function 530 1.07e-176
protein binding Hs molecular function 530 1.07e-176
nucleus Hs cellular component 494 6.80e-163
cytoplasm Hs cellular component 530 1.07e-176
endosome Hs cellular component 530 1.07e-176
plasma membrane Hs cellular component 530 1.07e-176
integral component of plasma membrane Hs cellular component 494 6.80e-163
focal adhesion Hs cellular component 530 1.07e-176
integrin complex Hs cellular component 530 1.07e-176
external side of plasma membrane Hs cellular component 530 1.07e-176
cell surface Hs cellular component 530 1.07e-176
intercalated disc Hs cellular component 530 1.07e-176
coreceptor activity Hs molecular function 530 1.07e-176
membrane Hs cellular component 530 1.07e-176
integral component of membrane Hs cellular component 530 1.07e-176
fibroblast growth factor binding Hs molecular function 494 6.80e-163
enzyme binding Hs molecular function 494 6.80e-163
protein kinase binding Hs molecular function 495 1.12e-163
C-X3-C chemokine binding Hs molecular function 530 1.07e-176
lamellipodium Hs cellular component 530 1.07e-176
cell junction Hs cellular component 530 1.07e-176
filopodium Hs cellular component 530 1.07e-176
ICAM-3 receptor activity Hs molecular function 495 1.12e-163
heat shock protein binding Hs molecular function 495 1.12e-163
platelet alpha granule membrane Hs cellular component 494 6.80e-163
lamellipodium membrane Hs cellular component 494 6.80e-163
cytoplasmic vesicle Hs cellular component 530 1.07e-176
filopodium membrane Hs cellular component 494 6.80e-163
microvillus membrane Hs cellular component 494 6.80e-163
neuromuscular junction Hs cellular component 530 1.07e-176
insulin-like growth factor I binding Hs molecular function 494 6.80e-163
cleavage furrow Hs cellular component 530 1.07e-176
ruffle membrane Hs cellular component 530 1.07e-176
integrin alpha1-beta1 complex Hs cellular component 530 1.07e-176
integrin alpha2-beta1 complex Hs cellular component 530 1.07e-176
integrin alpha3-beta1 complex Hs cellular component 530 1.07e-176
integrin alpha7-beta1 complex Hs cellular component 530 1.07e-176
integrin alpha8-beta1 complex Hs cellular component 530 1.07e-176
integrin alpha10-beta1 complex Hs cellular component 530 1.07e-176
integrin alpha11-beta1 complex Hs cellular component 530 1.07e-176
integrin alphav-beta3 complex Hs cellular component 494 6.80e-163
integrin alphaL-beta2 complex Hs cellular component 495 1.12e-163
integrin alphaM-beta2 complex Hs cellular component 495 1.12e-163
specific granule membrane Hs cellular component 495 1.12e-163
myelin sheath abaxonal region Hs cellular component 530 1.07e-176
alphav-beta3 integrin-PKCalpha complex Hs cellular component 494 6.80e-163
alphav-beta3 integrin-IGF-1-IGF1R complex Hs cellular component 494 6.80e-163
alphav-beta3 integrin-HMGB1 complex Hs cellular component 494 6.80e-163
neuregulin binding Hs molecular function 494 6.80e-163
sarcolemma Hs cellular component 530 1.07e-176
melanosome Hs cellular component 530 1.07e-176
identical protein binding Hs molecular function 494 6.80e-163
cell projection Hs cellular component 530 1.07e-176
vascular endothelial growth factor receptor 2 binding Hs molecular function 494 6.80e-163
dendritic spine Hs cellular component 530 1.07e-176
receptor complex Hs cellular component 530 1.07e-176
laminin binding Hs molecular function 530 1.07e-176
plasma membrane raft Hs cellular component 495 1.12e-163
macromolecular complex binding Hs molecular function 530 1.07e-176
membrane raft Hs cellular component 530 1.07e-176
synapse Hs cellular component 530 1.07e-176
cadherin binding Hs molecular function 530 1.07e-176
metal ion binding Hs molecular function 530 1.07e-176
protein heterodimerization activity Hs molecular function 530 1.07e-176
perinuclear region of cytoplasm Hs cellular component 530 1.07e-176
cell adhesion molecule binding Hs molecular function 530 1.07e-176
extracellular matrix binding Hs molecular function 494 6.80e-163
recycling endosome Hs cellular component 530 1.07e-176
extracellular exosome Hs cellular component 530 1.07e-176
tertiary granule membrane Hs cellular component 495 1.12e-163
alphav-beta3 integrin-vitronectin complex Hs cellular component 494 6.80e-163
invadopodium membrane Hs cellular component 530 1.07e-176
synaptic membrane Hs cellular component 530 1.07e-176
collagen binding involved in cell-matrix adhesion Hs molecular function 530 1.07e-176
cytoplasmic region Hs cellular component 495 1.12e-163
ficolin-1-rich granule membrane Hs cellular component 495 1.12e-163
extracellular vesicle Hs cellular component 495 1.12e-163

GO (InterProScan)

No result

GO Term Analysis Type e-value