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Gene Card

Best human hits

AGO1; AGO2; AGO3

Species

H.roretzi

Unique Gene ID

Harore.g00000738

Gene Model ID

Harore.CG.MTP2014.S472.g00738

Location

S472:37092..45257

Transcript Models and Sequences

  Harore.CG.MTP2014.S472.g00738.01.t
Harore.CG.MTP2014.S472.g00738.02.t
Harore.CG.MTP2014.S472.g00738.03.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
Piwi Pfam Piwi domain
Piwi ProSiteProfiles Piwi domain
RNaseH_sf Gene3D Ribonuclease H superfamily
ArgoL1 Pfam Argonaute, linker 1 domain
PAZ_dom_sf SUPERFAMILY PAZ domain superfamily
Piwi SMART Piwi domain
PAZ_dom ProSiteProfiles PAZ domain
Argonaute_N Pfam Protein argonaute, N-terminal
Argonaute_Mid_dom Pfam Protein argonaute, Mid domain
PAZ_dom Pfam PAZ domain
PAZ_dom SMART PAZ domain
RNaseH-like_sf SUPERFAMILY Ribonuclease H-like superfamily
ArgoL2 Pfam Argonaute linker 2 domain
ArgoL1 SMART Argonaute, linker 1 domain

GOSlim

46 results

GO Term Annotation Origin Type
nuclear-transcribed mRNA catabolic process Orthology biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
nucleic acid binding Orthology molecular function
RNA binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
mRNA catabolic process Orthology biological process
translational initiation Orthology biological process
protein C-terminus binding Orthology molecular function
positive regulation of gene expression Orthology biological process
membrane Orthology cellular component
hydrolase activity Orthology molecular function
cell junction Orthology cellular component
transcription regulatory region DNA binding Orthology molecular function
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
extracellular exosome Orthology cellular component
nuclear body Orthology cellular component
negative regulation of apoptotic process Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
cytoplasmic part Orthology cellular component
macromolecular complex Orthology cellular component
enzyme binding Orthology molecular function
regulation of gene expression Orthology biological process
RNA metabolic process Orthology biological process
intracellular part Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
multicellular organism development Orthology biological process
angiogenesis Orthology biological process
RNA processing Orthology biological process
negative regulation of gene expression Orthology biological process
cellular process Orthology biological process
regulation of cell proliferation Orthology biological process
cell division Orthology biological process
cell migration Orthology biological process
reproductive process Orthology biological process
male gamete generation Orthology biological process
animal organ development Orthology biological process
cell morphogenesis Orthology biological process

GO (Orthology)

76 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
RNA 7-methylguanosine cap binding Hs molecular function
condensed nuclear chromosome Hs cellular component
P-body Hs cellular component
nuclear-transcribed mRNA catabolic process Hs biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II core binding Hs molecular function
core promoter binding Hs molecular function
nucleic acid binding Hs molecular function
RNA binding Hs molecular function
double-stranded RNA binding Hs molecular function
single-stranded RNA binding Hs molecular function
mRNA binding Hs molecular function
translation initiation factor activity Hs molecular function
nuclease activity Hs molecular function
endonuclease activity Hs molecular function
endoribonuclease activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
polysome Hs cellular component
mRNA cap binding complex Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
mRNA catabolic process Hs biological process
translation Hs biological process
translational initiation Hs biological process
regulation of translation Hs biological process
Wnt signaling pathway, calcium modulating pathway Hs biological process
protein C-terminus binding Hs molecular function
post-embryonic development Hs biological process
RNA secondary structure unwinding Hs biological process
miRNA metabolic process Hs biological process
positive regulation of gene expression Hs biological process
membrane Hs cellular component
RISC complex Hs cellular component
negative regulation of angiogenesis Hs biological process
hydrolase activity Hs molecular function
cell junction Hs cellular component
production of siRNA involved in RNA interference Hs biological process
dendrite Hs cellular component
intracellular ribonucleoprotein complex Hs cellular component
gene silencing by RNA Hs biological process
pre-miRNA processing Hs biological process
micro-ribonucleoprotein complex Hs cellular component
siRNA loading onto RISC involved in RNA interference Hs biological process
production of miRNAs involved in gene silencing by miRNA Hs biological process
siRNA binding Hs molecular function
miRNA binding Hs molecular function
miRNA mediated inhibition of translation Hs biological process
mRNA cleavage involved in gene silencing by miRNA Hs biological process
miRNA loading onto RISC involved in gene silencing by miRNA Hs biological process
cytoplasmic ribonucleoprotein granule Hs cellular component
transcription regulatory region DNA binding Hs molecular function
positive regulation of angiogenesis Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
negative regulation of translational initiation Hs biological process
metal ion binding Hs molecular function
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening Hs biological process
regulation of gene silencing by miRNA Hs biological process
extracellular exosome Hs cellular component
endoribonuclease activity, cleaving siRNA-paired mRNA Hs molecular function
RISC-loading complex Hs cellular component
regulation of stem cell proliferation Hs biological process
RNA phosphodiester bond hydrolysis, endonucleolytic Hs biological process
endoribonuclease activity, cleaving miRNA-paired mRNA Hs molecular function
mRNA cap binding Hs molecular function
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Hs biological process
positive regulation of trophoblast cell migration Hs biological process
synaptonemal complex assembly Hs biological process
male meiotic nuclear division Hs biological process
male gonad development Hs biological process
nuclear body Hs cellular component
regulation of cell morphogenesis Hs biological process
negative regulation of apoptotic process Hs biological process

GO (Blast)

40 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA 7-methylguanosine cap binding Hs molecular function 1317 0.0
condensed nuclear chromosome Hs cellular component 1247 0.0
P-body Hs cellular component 1317 0.0
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 1280 0.0
RNA polymerase II core binding Hs molecular function 1317 0.0
core promoter binding Hs molecular function 1317 0.0
nucleic acid binding Hs molecular function 1317 0.0
RNA binding Hs molecular function 1317 0.0
double-stranded RNA binding Hs molecular function 1317 0.0
single-stranded RNA binding Hs molecular function 1317 0.0
mRNA binding Hs molecular function 1317 0.0
translation initiation factor activity Hs molecular function 1317 0.0
nuclease activity Hs molecular function 1317 0.0
endonuclease activity Hs molecular function 1317 0.0
endoribonuclease activity Hs molecular function 1317 0.0
protein binding Hs molecular function 1317 0.0
nucleus Hs cellular component 1317 0.0
nucleoplasm Hs cellular component 1317 0.0
cytoplasm Hs cellular component 1317 0.0
cytosol Hs cellular component 1317 0.0
polysome Hs cellular component 1317 0.0
mRNA cap binding complex Hs cellular component 1317 0.0
protein C-terminus binding Hs molecular function 1317 0.0
membrane Hs cellular component 1317 0.0
RISC complex Hs cellular component 1317 0.0
hydrolase activity Hs molecular function 1317 0.0
cell junction Hs cellular component 1317 0.0
dendrite Hs cellular component 1317 0.0
intracellular ribonucleoprotein complex Hs cellular component 1317 0.0
micro-ribonucleoprotein complex Hs cellular component 1317 0.0
siRNA binding Hs molecular function 1317 0.0
miRNA binding Hs molecular function 1317 0.0
cytoplasmic ribonucleoprotein granule Hs cellular component 1247 0.0
transcription regulatory region DNA binding Hs molecular function 1280 0.0
metal ion binding Hs molecular function 1317 0.0
extracellular exosome Hs cellular component 1317 0.0
endoribonuclease activity, cleaving siRNA-paired mRNA Hs molecular function 1317 0.0
RISC-loading complex Hs cellular component 1317 0.0
endoribonuclease activity, cleaving miRNA-paired mRNA Hs molecular function 1317 0.0
mRNA cap binding Hs molecular function 1317 0.0

GO (InterProScan)

2 results

GO Term Analysis Type e-value
nucleic acid binding Gene3D molecular function 1.4E-132
protein binding SUPERFAMILY molecular function 5.18E-63

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