Gene Card
Best human hits
CSK; MAP3K13; MLKL
Species
Unique Gene ID
Harore.g00011299
Gene Model ID
Harore.CG.MTP2014.S544.g11299
Location
S544:39583..41498
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Adaptor_Cbl_N_dom_sf | Gene3D | Adaptor protein Cbl, N-terminal domain superfamily |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Blast | molecular function |
signal transducer activity | Orthology | molecular function |
receptor binding | Blast | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
protein C-terminus binding | Blast | molecular function |
programmed cell death | Orthology | biological process |
membrane | Orthology | cellular component |
kinase activity | Blast | molecular function |
transferase activity | Blast | molecular function |
protein kinase binding | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
macromolecular complex binding | Orthology | molecular function |
membrane raft | Blast | cellular component |
metal ion binding | Blast | molecular function |
extracellular exosome | Blast | cellular component |
protein homooligomerization | Orthology | biological process |
positive regulation of catalytic activity | Blast | biological process |
positive regulation of signal transduction | Blast | biological process |
cell junction | Blast | cellular component |
macromolecular complex | Blast | cellular component |
enzyme binding | Blast | molecular function |
intracellular part | Blast | cellular component |
plasma membrane part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
protein kinase activity | Hs | molecular function |
signal transducer activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
protein phosphorylation | Hs | biological process |
cell surface receptor signaling pathway | Hs | biological process |
programmed cell death | Hs | biological process |
membrane | Hs | cellular component |
protein kinase binding | Hs | molecular function |
intracellular signal transduction | Hs | biological process |
macromolecular complex binding | Hs | molecular function |
protein homotrimerization | Hs | biological process |
necroptotic process | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 136 | 1.33e-35 |
protein kinase activity | Hs | molecular function | 136 | 1.33e-35 |
protein serine/threonine kinase activity | Hs | molecular function | 77.0 | 6.39e-15 |
MAP kinase kinase kinase activity | Hs | molecular function | 77.0 | 6.39e-15 |
protein tyrosine kinase activity | Hs | molecular function | 76.3 | 5.68e-15 |
non-membrane spanning protein tyrosine kinase activity | Hs | molecular function | 76.3 | 5.68e-15 |
signal transducer activity | Hs | molecular function | 136 | 1.33e-35 |
receptor binding | Hs | molecular function | 76.3 | 5.68e-15 |
protein binding | Hs | molecular function | 136 | 1.33e-35 |
ATP binding | Hs | molecular function | 136 | 1.33e-35 |
cytoplasm | Hs | cellular component | 136 | 1.33e-35 |
cytosol | Hs | cellular component | 136 | 1.33e-35 |
plasma membrane | Hs | cellular component | 136 | 1.33e-35 |
cell-cell junction | Hs | cellular component | 76.3 | 5.68e-15 |
protein C-terminus binding | Hs | molecular function | 76.3 | 5.68e-15 |
IkappaB kinase complex | Hs | cellular component | 77.0 | 6.39e-15 |
membrane | Hs | cellular component | 136 | 1.33e-35 |
kinase activity | Hs | molecular function | 77.0 | 6.39e-15 |
transferase activity | Hs | molecular function | 77.0 | 6.39e-15 |
protein kinase binding | Hs | molecular function | 136 | 1.33e-35 |
protein phosphatase binding | Hs | molecular function | 76.3 | 5.68e-15 |
extrinsic component of cytoplasmic side of plasma membrane | Hs | cellular component | 76.3 | 5.68e-15 |
protein kinase A catalytic subunit binding | Hs | molecular function | 76.3 | 5.68e-15 |
identical protein binding | Hs | molecular function | 77.0 | 6.39e-15 |
protein homodimerization activity | Hs | molecular function | 77.0 | 6.39e-15 |
macromolecular complex binding | Hs | molecular function | 136 | 1.33e-35 |
membrane raft | Hs | cellular component | 76.3 | 5.68e-15 |
metal ion binding | Hs | molecular function | 77.0 | 6.39e-15 |
extracellular exosome | Hs | cellular component | 76.3 | 5.68e-15 |
proline-rich region binding | Hs | molecular function | 76.3 | 5.68e-15 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 2.2E-29 |
signal transducer activity | Gene3D | molecular function | 2.0E-19 |
ATP binding | ProSiteProfiles | molecular function | 21.87 |
protein phosphorylation | Pfam | biological process | 2.2E-29 |
cell surface receptor signaling pathway | Gene3D | biological process | 2.0E-19 |