Gene Card
Best human hits
FAT4; NOTCH1; NOTCH3
Species
Unique Gene ID
Harore.g00013934
Gene Model ID
Harore.CG.MTP2014.S651.g13934
Location
S651:7132..17809
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
9 results
| IPR Term | Analysis | Definition |
|---|---|---|
| EGF-type_Asp/Asn_hydroxyl_site | ProSitePatterns | EGF-type aspartate/asparagine hydroxylation site |
| EGF-like_dom | ProSiteProfiles | EGF-like domain |
| EGF-like_Ca-bd_dom | Pfam | EGF-like calcium-binding domain |
| EGF-like_CS | ProSitePatterns | EGF-like, conserved site |
| EGF-like_dom | Pfam | EGF-like domain |
| EGF_Ca-bd_CS | ProSitePatterns | EGF-like calcium-binding, conserved site |
| Growth_fac_rcpt_cys_sf | SUPERFAMILY | Growth factor receptor cysteine-rich domain superfamily |
| EGF-like_Ca-bd_dom | SMART | EGF-like calcium-binding domain |
| EGF-like_dom | SMART | EGF-like domain |
GOSlim
43 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| Golgi membrane | Blast | cellular component |
| chromatin binding | Blast | molecular function |
| transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
| transmembrane signaling receptor activity | Blast | molecular function |
| calcium ion binding | Orthology | molecular function |
| protein binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| intracellular | Blast | cellular component |
| nucleus | Blast | cellular component |
| nucleoplasm | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| endoplasmic reticulum membrane | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| cytosol | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| adherens junction | Blast | cellular component |
| Notch signaling pathway | Orthology | biological process |
| cell surface | Blast | cellular component |
| membrane | Orthology | cellular component |
| integral component of membrane | Orthology | cellular component |
| apical plasma membrane | Blast | cellular component |
| enzyme binding | Blast | molecular function |
| cell differentiation | Orthology | biological process |
| cytoplasmic vesicle | Blast | cellular component |
| identical protein binding | Blast | molecular function |
| sequence-specific DNA binding | Blast | molecular function |
| apical part of cell | Blast | cellular component |
| metal ion binding | Blast | molecular function |
| protein heterodimerization activity | Blast | molecular function |
| extracellular exosome | Orthology | cellular component |
| cell periphery | Blast | cellular component |
| extracellular space | Orthology | cellular component |
| protein homodimerization activity | Orthology | molecular function |
| negative regulation of signal transduction | Orthology | biological process |
| transcription regulatory region DNA binding | Blast | molecular function |
| endomembrane system | Blast | cellular component |
| macromolecular complex | Blast | cellular component |
| enzyme regulator activity | Blast | molecular function |
| receptor binding | Blast | molecular function |
| cytoskeleton | Blast | cellular component |
| DNA binding | Blast | molecular function |
| cell adhesion molecule binding | Blast | molecular function |
GO (Orthology)
8 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| calcium ion binding | Hs | molecular function |
| membrane | Hs | cellular component |
| integral component of membrane | Hs | cellular component |
| cell differentiation | Hs | biological process |
| negative regulation of Notch signaling pathway | Hs | biological process |
| extracellular exosome | Hs | cellular component |
| extracellular space | Hs | cellular component |
| protein homodimerization activity | Hs | molecular function |
GO (Blast)
41 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 107 | 1.31e-24 |
| core promoter binding | Hs | molecular function | 107 | 1.84e-24 |
| transcriptional activator activity, RNA polymerase II transcription factor binding | Hs | molecular function | 107 | 1.84e-24 |
| acrosomal vesicle | Hs | cellular component | 107 | 1.84e-24 |
| MAML1-RBP-Jkappa- ICN1 complex | Hs | cellular component | 107 | 1.84e-24 |
| chromatin binding | Hs | molecular function | 107 | 1.84e-24 |
| transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 107 | 1.84e-24 |
| enzyme inhibitor activity | Hs | molecular function | 107 | 1.84e-24 |
| receptor activity | Hs | molecular function | 107 | 1.31e-24 |
| transmembrane signaling receptor activity | Hs | molecular function | 107 | 1.84e-24 |
| Notch binding | Hs | molecular function | 107 | 1.84e-24 |
| calcium ion binding | Hs | molecular function | 108 | 9.83e-25 |
| protein binding | Hs | molecular function | 108 | 9.83e-25 |
| extracellular region | Hs | cellular component | 107 | 1.31e-24 |
| intracellular | Hs | cellular component | 108 | 9.83e-25 |
| nucleus | Hs | cellular component | 107 | 1.31e-24 |
| nucleoplasm | Hs | cellular component | 107 | 1.31e-24 |
| cytoplasm | Hs | cellular component | 107 | 1.84e-24 |
| endoplasmic reticulum | Hs | cellular component | 107 | 1.84e-24 |
| endoplasmic reticulum membrane | Hs | cellular component | 107 | 1.31e-24 |
| Golgi apparatus | Hs | cellular component | 107 | 1.84e-24 |
| cytosol | Hs | cellular component | 107 | 1.31e-24 |
| plasma membrane | Hs | cellular component | 108 | 9.83e-25 |
| adherens junction | Hs | cellular component | 107 | 1.84e-24 |
| cell surface | Hs | cellular component | 107 | 1.84e-24 |
| actin cytoskeleton | Hs | cellular component | 107 | 1.31e-24 |
| membrane | Hs | cellular component | 108 | 9.83e-25 |
| integral component of membrane | Hs | cellular component | 108 | 9.83e-25 |
| apical plasma membrane | Hs | cellular component | 107 | 1.84e-24 |
| enzyme binding | Hs | molecular function | 107 | 1.31e-24 |
| cytoplasmic vesicle | Hs | cellular component | 107 | 1.84e-24 |
| chromatin DNA binding | Hs | molecular function | 107 | 1.84e-24 |
| identical protein binding | Hs | molecular function | 107 | 1.31e-24 |
| receptor complex | Hs | cellular component | 107 | 1.31e-24 |
| sequence-specific DNA binding | Hs | molecular function | 107 | 1.84e-24 |
| apical part of cell | Hs | cellular component | 108 | 9.83e-25 |
| cadherin binding | Hs | molecular function | 107 | 1.31e-24 |
| metal ion binding | Hs | molecular function | 107 | 1.84e-24 |
| protein heterodimerization activity | Hs | molecular function | 107 | 1.84e-24 |
| extracellular exosome | Hs | cellular component | 108 | 9.83e-25 |
| cell periphery | Hs | cellular component | 107 | 1.84e-24 |
GO (InterProScan)
1 result
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| calcium ion binding | SMART | molecular function | 3.7E-12 |
