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GENE CARD

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Gene Card

Best human hits

SESN1; SESN2; SESN3

Species

H.roretzi

Unique Gene ID

Harore.g00002741

Gene Model ID

Harore.CG.MTP2014.S9.g02741

Location

S9:596026..597877

Transcript Models and Sequences

  Harore.CG.MTP2014.S9.g02741.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
Sestrin Pfam Sestrin
AhpD-like SUPERFAMILY AhpD-like
Sestrin PANTHER Sestrin

GOSlim

39 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
nucleus Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
cytosol Orthology cellular component
oxidation-reduction process Orthology biological process
nucleolus Orthology cellular component
regulation of cellular metabolic process Orthology biological process
protein phosphorylation Orthology biological process
guanyl ribonucleotide binding Orthology molecular function
anion binding Orthology molecular function
GTPase regulator activity Orthology molecular function
purine ribonucleoside binding Orthology molecular function
organelle organization Orthology biological process
response to organic substance Orthology biological process
catalytic activity Orthology molecular function
cellular component organization Orthology biological process
intracellular signal transduction Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
DNA metabolic process Orthology biological process
cell communication Orthology biological process
cellular response to stress Orthology biological process
response to oxidative stress Orthology biological process
organic substance transport Orthology biological process
transmembrane transport Orthology biological process
cell surface receptor signaling pathway Orthology biological process
regulation of signal transduction Orthology biological process
cellular response to organic substance Orthology biological process
cation binding Orthology molecular function
small molecule binding Orthology molecular function
cellular metabolic process Orthology biological process
protein localization to organelle Orthology biological process
negative regulation of signal transduction Orthology biological process
cytoplasmic part Orthology cellular component
regulation of catalytic activity Orthology biological process
molecular transducer activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function

GO (Orthology)

44 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
fibrillar center Hs cellular component
regulation of protein phosphorylation Hs biological process
GDP-dissociation inhibitor activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
cytosol Hs cellular component
fatty acid beta-oxidation Hs biological process
mitochondrion organization Hs biological process
response to glucose Hs biological process
positive regulation of macroautophagy Hs biological process
oxidoreductase activity Hs molecular function
oxidoreductase activity, acting on peroxide as acceptor Hs molecular function
negative regulation of cell growth Hs biological process
DNA damage response, signal transduction by p53 class mediator Hs biological process
nucleotide-activated protein kinase complex Hs cellular component
TORC2 complex Hs cellular component
mitochondrial DNA metabolic process Hs biological process
sulfiredoxin activity Hs molecular function
response to insulin Hs biological process
cellular response to amino acid starvation Hs biological process
cellular response to oxidative stress Hs biological process
TORC2 signaling Hs biological process
cellular response to glucose starvation Hs biological process
glucose homeostasis Hs biological process
protein kinase B signaling Hs biological process
glucose import Hs biological process
regulation of insulin receptor signaling pathway Hs biological process
regulation of protein kinase B signaling Hs biological process
peroxiredoxin activity Hs molecular function
oxidation-reduction process Hs biological process
GATOR2 complex Hs cellular component
triglyceride homeostasis Hs biological process
leucine binding Hs molecular function
cellular response to amino acid stimulus Hs biological process
reactive oxygen species metabolic process Hs biological process
cellular oxidant detoxification Hs biological process
positive regulation of protein localization to nucleus Hs biological process
regulation of response to reactive oxygen species Hs biological process
negative regulation of TORC1 signaling Hs biological process
cellular response to leucine starvation Hs biological process
ATG1/ULK1 kinase complex Hs cellular component
regulation of cAMP-dependent protein kinase activity Hs biological process

GO (Blast)

16 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
fibrillar center Hs cellular component 442 1.67e-149
GDP-dissociation inhibitor activity Hs molecular function 402 1.44e-134
protein binding Hs molecular function 442 1.67e-149
nucleus Hs cellular component 442 1.67e-149
cytoplasm Hs cellular component 442 1.67e-149
mitochondrion Hs cellular component 402 1.44e-134
cytosol Hs cellular component 442 1.67e-149
oxidoreductase activity Hs molecular function 442 1.67e-149
oxidoreductase activity, acting on peroxide as acceptor Hs molecular function 402 1.44e-134
nucleotide-activated protein kinase complex Hs cellular component 402 1.44e-134
TORC2 complex Hs cellular component 435 2.42e-147
sulfiredoxin activity Hs molecular function 402 1.44e-134
peroxiredoxin activity Hs molecular function 442 1.67e-149
GATOR2 complex Hs cellular component 442 1.67e-149
leucine binding Hs molecular function 442 1.67e-149
ATG1/ULK1 kinase complex Hs cellular component 402 1.44e-134

GO (InterProScan)

2 results

GO Term Analysis Type e-value
nucleus Pfam cellular component 8.0E-166
regulation of response to reactive oxygen species Pfam biological process 8.0E-166