Gene Card
Best human hits
USP11; USP2; USP8
Unique Gene ID
Cirobu.g00000735
Gene Model ID
KH2012:KH.C1.491
Location
KhC1:6017299..6021237
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000000779 |
NCBI Reference Sequence | XM_018813078.1 |
cien102212
Plate: VES86_A07
cien45312
Plate: VES77_C11
ciad075k23
Plate: R1CiGC07b19
citb081g18
Plate: R1CiGC46b17
n/a
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IPR Term | Analysis | Definition |
---|---|---|
USP_CS | ProSitePatterns | Ubiquitin specific protease, conserved site |
Peptidase_C19_UCH | Pfam | Peptidase C19, ubiquitin carboxyl-terminal hydrolase |
USP_dom | ProSiteProfiles | Ubiquitin specific protease domain |
Rhodanese-like_dom | ProSiteProfiles | Rhodanese-like domain |
Rhodanese-like_dom_sf | SUPERFAMILY | Rhodanese-like domain superfamily |
Rhodanese-like_dom_sf | Gene3D | Rhodanese-like domain superfamily |
Rhodanese-like_dom | SMART | Rhodanese-like domain |
USP8_dimer | Pfam | USP8 dimerisation domain |
Rhodanese-like_dom | Pfam | Rhodanese-like domain |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Orthology | cellular component |
endosome | Orthology | cellular component |
early endosome | Orthology | cellular component |
centrosome | Blast | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
proteolysis | Orthology | biological process |
cell cycle | Orthology | biological process |
peptidase activity | Orthology | molecular function |
cell proliferation | Orthology | biological process |
membrane | Orthology | cellular component |
hydrolase activity | Orthology | molecular function |
midbody | Orthology | cellular component |
ubiquitin protein ligase binding | Blast | molecular function |
identical protein binding | Blast | molecular function |
metal ion binding | Blast | molecular function |
perinuclear region of cytoplasm | Blast | cellular component |
positive regulation of canonical Wnt signaling pathway | Orthology | biological process |
membrane organization | Orthology | biological process |
cell division | Orthology | biological process |
endopeptidase activity | Orthology | molecular function |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
organelle organization | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
whole membrane | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
organelle | Orthology | cellular component |
postsynapse | Orthology | cellular component |
neuron part | Orthology | cellular component |
plasma membrane part | Orthology | cellular component |
membrane part | Orthology | cellular component |
cell adhesion molecule binding | Orthology | molecular function |
intracellular non-membrane-bounded organelle | Blast | cellular component |
cell periphery | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
mitotic cytokinesis | Hs | biological process |
cysteine-type endopeptidase activity | Hs | molecular function |
thiol-dependent ubiquitin-specific protease activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
endosome | Hs | cellular component |
early endosome | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
proteolysis | Hs | biological process |
ubiquitin-dependent protein catabolic process | Hs | biological process |
endosome organization | Hs | biological process |
cell cycle | Hs | biological process |
peptidase activity | Hs | molecular function |
cysteine-type peptidase activity | Hs | molecular function |
cell proliferation | Hs | biological process |
endosome membrane | Hs | cellular component |
postsynaptic density | Hs | cellular component |
membrane | Hs | cellular component |
protein deubiquitination | Hs | biological process |
hydrolase activity | Hs | molecular function |
SH3 domain binding | Hs | molecular function |
extrinsic component of plasma membrane | Hs | cellular component |
midbody | Hs | cellular component |
extrinsic component of endosome membrane | Hs | cellular component |
thiol-dependent ubiquitinyl hydrolase activity | Hs | molecular function |
dendritic spine | Hs | cellular component |
cadherin binding | Hs | molecular function |
protein K63-linked deubiquitination | Hs | biological process |
protein K48-linked deubiquitination | Hs | biological process |
positive regulation of canonical Wnt signaling pathway | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
cysteine-type endopeptidase activity | Hs | molecular function | 419 | 2.57e-128 |
thiol-dependent ubiquitin-specific protease activity | Hs | molecular function | 419 | 2.57e-128 |
protein binding | Hs | molecular function | 419 | 2.57e-128 |
nucleus | Hs | cellular component | 419 | 2.57e-128 |
nucleoplasm | Hs | cellular component | 224 | 9.96e-63 |
chromosome | Hs | cellular component | 206 | 2.07e-54 |
cytoplasm | Hs | cellular component | 419 | 2.57e-128 |
endosome | Hs | cellular component | 419 | 2.57e-128 |
early endosome | Hs | cellular component | 419 | 2.57e-128 |
centrosome | Hs | cellular component | 224 | 9.96e-63 |
cytosol | Hs | cellular component | 419 | 2.57e-128 |
plasma membrane | Hs | cellular component | 419 | 2.57e-128 |
cell cortex | Hs | cellular component | 224 | 9.96e-63 |
peptidase activity | Hs | molecular function | 419 | 2.57e-128 |
cysteine-type peptidase activity | Hs | molecular function | 419 | 2.57e-128 |
endosome membrane | Hs | cellular component | 419 | 2.57e-128 |
postsynaptic density | Hs | cellular component | 419 | 2.57e-128 |
membrane | Hs | cellular component | 419 | 2.57e-128 |
hydrolase activity | Hs | molecular function | 419 | 2.57e-128 |
SH3 domain binding | Hs | molecular function | 419 | 2.57e-128 |
extrinsic component of plasma membrane | Hs | cellular component | 419 | 2.57e-128 |
cyclin binding | Hs | molecular function | 224 | 9.96e-63 |
midbody | Hs | cellular component | 419 | 2.57e-128 |
extrinsic component of endosome membrane | Hs | cellular component | 419 | 2.57e-128 |
ubiquitin protein ligase binding | Hs | molecular function | 224 | 9.96e-63 |
thiol-dependent ubiquitinyl hydrolase activity | Hs | molecular function | 419 | 2.57e-128 |
identical protein binding | Hs | molecular function | 224 | 9.96e-63 |
dendritic spine | Hs | cellular component | 419 | 2.57e-128 |
cadherin binding | Hs | molecular function | 419 | 2.57e-128 |
metal ion binding | Hs | molecular function | 224 | 9.96e-63 |
perinuclear region of cytoplasm | Hs | cellular component | 224 | 9.96e-63 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ubiquitin-dependent protein catabolic process | ProSitePatterns | biological process | |
protein deubiquitination | Pfam | biological process | 1.3E-70 |
thiol-dependent ubiquitinyl hydrolase activity | Pfam | molecular function | 1.3E-70 |