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GENE CARD

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Gene Card

Best human hits

NFE2; NFE2L1; NFE2L2

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00000992

Gene Model ID

KH2012:KH.C1.725

Location

KhC1:4578930..4594593

Transcript Models and Sequences

  KH2012:KH.C1.725.v1.A.ND3-1
KH2012:KH.C1.725.v2.A.SL1-1
KH2012:KH.C1.725.v2.A.SL2-1
KH2012:KH.C1.725.v3.A.SL4-1
KH2012:KH.C1.725.v4.A.SL4-1

External Database Gene Card

External database links

6 results

Database Gene ID
ENSEMBL ENSCING00000003373
NCBI Reference Sequence NM_001078302.1
NCBI Reference Sequence NM_001093743.1
NCBI Reference Sequence XM_009863806.2
NCBI Reference Sequence XM_018814873.1
NCBI Reference Sequence XM_018814891.1
Collections

Gateway full ORF

4 results

cien104109

Plate: VES86_H15

cima895685

Plate: VES71_C21

cima8116139

Plate: VES74_B15

cien127206

Plate: VES90_L05

Gene collection 1 (N. Satoh)

2 results

cicl015m17

Plate: R1CiGC10a10

ciad028c17

Plate: R1CiGC03f19

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
bZIP SMART Basic-leucine zipper domain
bZIP ProSitePatterns Basic-leucine zipper domain
TF_DNA-bd_sf SUPERFAMILY Transcription factor, Skn-1-like, DNA-binding domain superfamily
bZIP_Maf Pfam Basic leucine zipper domain, Maf-type
bZIP ProSiteProfiles Basic-leucine zipper domain

GOSlim

67 results

GO Term Annotation Origin Type
transcription regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
core promoter proximal region sequence-specific DNA binding Orthology molecular function
DNA binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription cofactor activity Orthology molecular function
transcription coactivator activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
endoplasmic reticulum Orthology cellular component
endoplasmic reticulum membrane Orthology cellular component
Golgi apparatus Orthology cellular component
centrosome Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
multicellular organism development Orthology biological process
blood coagulation Orthology biological process
hemostasis Orthology biological process
transcription factor binding Orthology molecular function
anatomical structure morphogenesis Orthology biological process
positive regulation of gene expression Orthology biological process
membrane Orthology cellular component
integral component of membrane Orthology cellular component
protein ubiquitination Orthology biological process
macromolecular complex Orthology cellular component
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
macromolecular complex binding Orthology molecular function
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
protein N-terminus binding Orthology molecular function
negative regulation of cell death Orthology biological process
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
intracellular organelle part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
organelle organization Orthology biological process
organic substance metabolic process Orthology biological process
defense response Orthology biological process
developmental process Orthology biological process
binding Orthology molecular function
proteolysis Orthology biological process
negative regulation of apoptotic process Orthology biological process
neuron projection development Orthology biological process
nuclear body Orthology cellular component
immune system process Orthology biological process
animal organ development Orthology biological process
cell differentiation Orthology biological process
signal transduction Orthology biological process
cellular response to stress Orthology biological process
cellular response to organic substance Orthology biological process
response to oxidative stress Orthology biological process
cell communication Orthology biological process
cell Orthology cellular component
angiogenesis Orthology biological process
organic substance transport Orthology biological process
transmembrane transport Orthology biological process
response to hypoxia Orthology biological process
intracellular signal transduction Orthology biological process
negative regulation of signal transduction Orthology biological process

GO (Orthology)

84 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
chromatin Hs cellular component
transcription regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II distal enhancer sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II activating transcription factor binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription factor binding Hs molecular function
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
transcription cofactor binding Hs molecular function
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription cofactor activity Hs molecular function
transcription coactivator activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
endoplasmic reticulum membrane Hs cellular component
Golgi apparatus Hs cellular component
centrosome Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
nucleosome disassembly Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription from RNA polymerase II promoter Hs biological process
lipid metabolic process Hs biological process
heme biosynthetic process Hs biological process
inflammatory response Hs biological process
multicellular organism development Hs biological process
aging Hs biological process
blood coagulation Hs biological process
hemostasis Hs biological process
blood circulation Hs biological process
transcription factor binding Hs molecular function
steroid metabolic process Hs biological process
cholesterol metabolic process Hs biological process
lipid binding Hs molecular function
anatomical structure morphogenesis Hs biological process
proteasomal ubiquitin-independent protein catabolic process Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of cardiac muscle cell apoptotic process Hs biological process
positive regulation of neuron projection development Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
protein ubiquitination Hs biological process
PML body Hs cellular component
protein domain specific binding Hs molecular function
positive regulation of blood coagulation Hs biological process
erythrocyte differentiation Hs biological process
endoplasmic reticulum unfolded protein response Hs biological process
macromolecular complex Hs cellular component
protein-DNA complex Hs cellular component
cellular response to oxidative stress Hs biological process
response to endoplasmic reticulum stress Hs biological process
positive regulation of transcription from RNA polymerase II promoter in response to stress Hs biological process
PERK-mediated unfolded protein response Hs biological process
cellular response to glucose starvation Hs biological process
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
macromolecular complex binding Hs molecular function
cell redox homeostasis Hs biological process
positive regulation of angiogenesis Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
regulation of embryonic development Hs biological process
positive regulation of glucose import Hs biological process
protein N-terminus binding Hs molecular function
WW domain binding Hs molecular function
negative regulation of cell death Hs biological process
cellular response to hydrogen peroxide Hs biological process
cellular response to tumor necrosis factor Hs biological process
cellular response to hypoxia Hs biological process
cellular response to fluid shear stress Hs biological process
negative regulation of hematopoietic stem cell differentiation Hs biological process
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway Hs biological process
negative regulation of hydrogen peroxide-induced cell death Hs biological process
positive regulation of reactive oxygen species metabolic process Hs biological process
negative regulation of transcription from RNA polymerase II promoter Hs biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function

GO (Blast)

36 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
chromatin Hs cellular component 147 1.10e-36
transcription regulatory region sequence-specific DNA binding Hs molecular function 160 1.51e-40
RNA polymerase II distal enhancer sequence-specific DNA binding Hs molecular function 160 1.51e-40
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 160 1.51e-40
core promoter proximal region sequence-specific DNA binding Hs molecular function 143 6.49e-37
RNA polymerase II activating transcription factor binding Hs molecular function 147 1.10e-36
transcriptional activator activity, RNA polymerase II transcription factor binding Hs molecular function 160 1.51e-40
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 160 1.51e-40
transcription cofactor binding Hs molecular function 147 1.10e-36
DNA binding Hs molecular function 160 1.51e-40
transcription factor activity, sequence-specific DNA binding Hs molecular function 160 1.51e-40
transcription cofactor activity Hs molecular function 160 1.51e-40
transcription coactivator activity Hs molecular function 143 6.49e-37
protein binding Hs molecular function 160 1.51e-40
nucleus Hs cellular component 160 1.51e-40
nucleoplasm Hs cellular component 147 1.10e-36
cytoplasm Hs cellular component 160 1.51e-40
endoplasmic reticulum Hs cellular component 160 1.51e-40
endoplasmic reticulum membrane Hs cellular component 160 1.51e-40
Golgi apparatus Hs cellular component 147 1.10e-36
centrosome Hs cellular component 147 1.10e-36
cytosol Hs cellular component 160 1.51e-40
plasma membrane Hs cellular component 147 1.10e-36
transcription factor binding Hs molecular function 147 1.10e-36
lipid binding Hs molecular function 160 1.51e-40
membrane Hs cellular component 160 1.51e-40
integral component of membrane Hs cellular component 160 1.51e-40
PML body Hs cellular component 143 6.49e-37
protein domain specific binding Hs molecular function 160 1.51e-40
macromolecular complex Hs cellular component 160 1.51e-40
protein-DNA complex Hs cellular component 147 1.10e-36
sequence-specific DNA binding Hs molecular function 147 1.10e-36
transcription regulatory region DNA binding Hs molecular function 147 1.10e-36
macromolecular complex binding Hs molecular function 160 1.51e-40
protein N-terminus binding Hs molecular function 143 6.49e-37
WW domain binding Hs molecular function 143 6.49e-37

GO (InterProScan)

4 results

GO Term Analysis Type e-value
DNA binding SUPERFAMILY molecular function 3.4E-23
transcription factor activity, sequence-specific DNA binding SMART molecular function 1.3E-9
nucleus Pfam cellular component 4.8E-15
regulation of transcription, DNA-templated SUPERFAMILY biological process 3.4E-23

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