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Gene Card

Best human hits

EXD2; EXD3; WRN

Unique Gene ID

Cirobu.g00005943

Gene Model ID

KH2012:KH.C3.740

Location

KhC3:652763..653538

External Database Gene Card

External database links

1 result

Database Gene ID
ENSEMBL ENSCING00000022002
Collections

Gateway full ORF

2 results

cien136418

Plate: VES91_I16

cien137483

Plate: VES91_E20

Gene collection 1 (N. Satoh)

2 results

cicl017e01

Plate: R1CiGC10b23

cign013d08

Plate: R1CiGC41p06

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
RNaseH_sf Gene3D Ribonuclease H superfamily
3'-5'_exonuclease_dom SMART 3'-5' exonuclease domain
3'-5'_exonuclease_dom Pfam 3'-5' exonuclease domain
RNaseH-like_sf SUPERFAMILY Ribonuclease H-like superfamily

GOSlim

30 results

GO Term Annotation Origin Type
nucleotide binding Blast molecular function
magnesium ion binding Blast molecular function
nucleic acid binding Blast molecular function
DNA binding Blast molecular function
chromatin binding Blast molecular function
catalytic activity Blast molecular function
protein binding Blast molecular function
ATP binding Blast molecular function
intracellular Blast cellular component
nucleus Blast cellular component
nucleoplasm Blast cellular component
nucleolus Blast cellular component
cytoplasm Blast cellular component
centrosome Blast cellular component
nucleobase-containing compound metabolic process InterProScan biological process
DNA metabolic process Blast biological process
nuclear speck Blast cellular component
hydrolase activity Blast molecular function
protein homodimerization activity Blast molecular function
neuron projection Blast cellular component
macromolecular complex binding Blast molecular function
metal ion binding Blast molecular function
intracellular organelle part Blast cellular component
intracellular non-membrane-bounded organelle Blast cellular component
organelle organization Blast biological process
nucleoside-triphosphatase activity Blast molecular function
transition metal ion binding Blast molecular function
nuclear part Blast cellular component
macromolecular complex Blast cellular component
sequence-specific DNA binding Blast molecular function

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type

GO (Blast)

46 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 160 5.37e-45
magnesium ion binding Hs molecular function 160 5.37e-45
four-way junction DNA binding Hs molecular function 160 5.37e-45
Y-form DNA binding Hs molecular function 160 5.37e-45
bubble DNA binding Hs molecular function 160 5.37e-45
chromosome, telomeric region Hs cellular component 160 5.37e-45
nucleic acid binding Hs molecular function 160 5.37e-45
DNA binding Hs molecular function 160 5.37e-45
DNA helicase activity Hs molecular function 160 5.37e-45
chromatin binding Hs molecular function 160 5.37e-45
catalytic activity Hs molecular function 160 5.37e-45
ATP-dependent DNA helicase activity Hs molecular function 160 5.37e-45
helicase activity Hs molecular function 160 5.37e-45
nuclease activity Hs molecular function 160 5.37e-45
exonuclease activity Hs molecular function 160 5.37e-45
protein binding Hs molecular function 160 5.37e-45
ATP binding Hs molecular function 160 5.37e-45
intracellular Hs cellular component 160 5.37e-45
nucleus Hs cellular component 160 5.37e-45
nucleoplasm Hs cellular component 160 5.37e-45
replication fork Hs cellular component 160 5.37e-45
nucleolus Hs cellular component 160 5.37e-45
cytoplasm Hs cellular component 160 5.37e-45
centrosome Hs cellular component 160 5.37e-45
ATP-dependent helicase activity Hs molecular function 160 5.37e-45
single-stranded DNA 3'-5' exodeoxyribonuclease activity Hs molecular function 55.1 6.68e-09
3'-5' exonuclease activity Hs molecular function 160 5.37e-45
exodeoxyribonuclease I activity Hs molecular function 55.1 6.68e-09
four-way junction helicase activity Hs molecular function 160 5.37e-45
nuclear speck Hs cellular component 160 5.37e-45
hydrolase activity Hs molecular function 160 5.37e-45
ATPase activity Hs molecular function 160 5.37e-45
manganese ion binding Hs molecular function 160 5.37e-45
MutLalpha complex Hs cellular component 160 5.37e-45
protein homodimerization activity Hs molecular function 160 5.37e-45
neuron projection Hs cellular component 160 5.37e-45
3'-5' DNA helicase activity Hs molecular function 160 5.37e-45
ATP-dependent 3'-5' DNA helicase activity Hs molecular function 160 5.37e-45
macromolecular complex binding Hs molecular function 160 5.37e-45
metal ion binding Hs molecular function 160 5.37e-45
G-quadruplex DNA binding Hs molecular function 160 5.37e-45
forked DNA-dependent helicase activity Hs molecular function 160 5.37e-45
telomeric D-loop binding Hs molecular function 160 5.37e-45
telomeric G-quadruplex DNA binding Hs molecular function 160 5.37e-45
3'-flap-structured DNA binding Hs molecular function 160 5.37e-45
8-hydroxy-2'-deoxyguanosine DNA binding Hs molecular function 160 5.37e-45

GO (InterProScan)

3 results

GO Term Analysis Type e-value
nucleic acid binding Gene3D molecular function 4.3E-52
nucleobase-containing compound metabolic process Pfam biological process 1.2E-24
3'-5' exonuclease activity Pfam molecular function 1.2E-24





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