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GENE CARD

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Gene Card

Best human hits

AURKA; AURKB; AURKC

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00008046

Gene Model ID

KH2012:KH.C7.219

Location

KhC7:1818153..1819609

Transcript Models and Sequences

  KH2012:KH.C7.219.v1.A.nonSL4-1
KH2012:KH.C7.219.v1.A.nonSL5-1
KH2012:KH.C7.219.v1.A.SL1-1
KH2012:KH.C7.219.v1.A.SL2-1
KH2012:KH.C7.219.v1.A.SL3-1
KH2012:KH.C7.219.v1.A.SL6-1

External Database Gene Card

External database links

1 result

Database Gene ID
ENSEMBL ENSCING00000000139
Collections

Gateway full ORF

3 results

cima813600

Plate: VES58_D15

cien134695

Plate: VES91_G10

cien212341

Plate: VES103_K05

Gene collection 1 (N. Satoh)

1 result

cieg023k05

Plate: R1CiGC19c04

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Prot_kinase_dom Pfam Protein kinase domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Aur PANTHER Aurora kinase
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Prot_kinase_dom SMART Protein kinase domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily

GOSlim

64 results

GO Term Annotation Origin Type
G2/M transition of mitotic cell cycle Orthology biological process
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
nucleotide binding Orthology molecular function
protein kinase activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
centrosome Orthology cellular component
microtubule organizing center Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
microtubule Orthology cellular component
protein phosphorylation Orthology biological process
cell cycle Orthology biological process
spermatogenesis Orthology biological process
cell proliferation Orthology biological process
response to wounding Orthology biological process
microtubule cytoskeleton Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
transferase activity Orthology molecular function
kinase binding Orthology molecular function
protein kinase binding Orthology molecular function
cell projection organization Orthology biological process
midbody Orthology cellular component
ubiquitin protein ligase binding Orthology molecular function
cell projection Orthology cellular component
negative regulation of apoptotic process Orthology biological process
protein autophosphorylation Orthology biological process
metal ion binding Orthology molecular function
protein heterodimerization activity Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
cell division Orthology biological process
reproductive process Orthology biological process
microtubule-based process Orthology biological process
organelle organization Orthology biological process
intracellular organelle part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
macromolecular complex Orthology cellular component
nuclear lumen Orthology cellular component
membrane organization Orthology biological process
cytoskeletal part Orthology cellular component
cytoplasmic part Orthology cellular component
organelle Orthology cellular component
plasma membrane region Orthology cellular component
gamete generation Orthology biological process
developmental process Orthology biological process
microtubule binding Orthology molecular function
multicellular organism development Orthology biological process
cellular protein modification process Orthology biological process
protein modification by small protein conjugation Orthology biological process
proteolysis Orthology biological process
regulation of molecular function Orthology biological process
DNA metabolic process Orthology biological process
transferase activity, transferring phosphorus-containing groups Orthology molecular function
protein localization to organelle Orthology biological process
cell projection part Orthology cellular component
axon Orthology cellular component
neuronal cell body Orthology cellular component
cell development Orthology biological process
neuron projection morphogenesis Orthology biological process

GO (Orthology)

102 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
G2/M transition of mitotic cell cycle Hs biological process
negative regulation of transcription from RNA polymerase II promoter Hs biological process
nucleotide binding Hs molecular function
meiotic spindle organization Hs biological process
microtubule cytoskeleton organization Hs biological process
mitotic cell cycle Hs biological process
chromosome, centromeric region Hs cellular component
kinetochore Hs cellular component
condensed chromosome, centromeric region Hs cellular component
condensed nuclear chromosome, centromeric region Hs cellular component
condensed chromosome Hs cellular component
cytokinesis Hs biological process
spindle pole Hs cellular component
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
protein serine/threonine/tyrosine kinase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
chromosome Hs cellular component
cytoplasm Hs cellular component
centrosome Hs cellular component
centriole Hs cellular component
microtubule organizing center Hs cellular component
spindle Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
microtubule Hs cellular component
spindle microtubule Hs cellular component
cilium Hs cellular component
protein phosphorylation Hs biological process
cell cycle Hs biological process
spindle organization Hs biological process
mitotic spindle organization Hs biological process
spindle assembly involved in female meiosis I Hs biological process
sister chromatid cohesion Hs biological process
centrosome cycle Hs biological process
mitotic centrosome separation Hs biological process
spermatogenesis Hs biological process
aging Hs biological process
cell proliferation Hs biological process
attachment of spindle microtubules to kinetochore Hs biological process
response to wounding Hs biological process
abscission Hs biological process
anterior/posterior axis specification Hs biological process
chromocenter Hs cellular component
regulation of G2/M transition of mitotic cell cycle Hs biological process
negative regulation of G2/M transition of mitotic cell cycle Hs biological process
microtubule cytoskeleton Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
histone modification Hs biological process
transferase activity Hs molecular function
protein sumoylation Hs biological process
kinase binding Hs molecular function
protein kinase binding Hs molecular function
cell projection organization Hs biological process
midbody Hs cellular component
anaphase-promoting complex-dependent catabolic process Hs biological process
spindle checkpoint Hs biological process
spindle pole centrosome Hs cellular component
ubiquitin protein ligase binding Hs molecular function
regulation of protein stability Hs biological process
negative regulation of protein binding Hs biological process
chromosome passenger complex Hs cellular component
positive regulation of telomere maintenance via telomerase Hs biological process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process Hs biological process
regulation of cytokinesis Hs biological process
negative regulation of cytokinesis Hs biological process
positive regulation of cytokinesis Hs biological process
protein localization to kinetochore Hs biological process
cellular response to UV Hs biological process
histone serine kinase activity Hs molecular function
histone-serine phosphorylation Hs biological process
cleavage furrow formation Hs biological process
germinal vesicle Hs cellular component
cell projection Hs cellular component
negative regulation of apoptotic process Hs biological process
axon hillock Hs cellular component
histone H3-S28 phosphorylation Hs biological process
mitotic cytokinesis checkpoint Hs biological process
pronucleus Hs cellular component
positive regulation of mitotic nuclear division Hs biological process
protein autophosphorylation Hs biological process
metal ion binding Hs molecular function
protein heterodimerization activity Hs molecular function
perinuclear region of cytoplasm Hs cellular component
oocyte development Hs biological process
spindle midzone Hs cellular component
mitotic spindle midzone assembly Hs biological process
cell division Hs biological process
meiotic cell cycle Hs biological process
centrosome localization Hs biological process
regulation of chromosome segregation Hs biological process
protein localization to centrosome Hs biological process
mitotic spindle Hs cellular component
meiotic spindle Hs cellular component
mitotic spindle pole Hs cellular component
positive regulation of oocyte maturation Hs biological process
mitotic spindle midzone Hs cellular component
neuron projection extension Hs biological process

GO (Blast)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 418 9.05e-147
chromosome, centromeric region Hs cellular component 380 1.71e-133
kinetochore Hs cellular component 365 7.40e-127
condensed chromosome, centromeric region Hs cellular component 365 7.40e-127
condensed nuclear chromosome, centromeric region Hs cellular component 418 9.05e-147
condensed chromosome Hs cellular component 380 1.71e-133
spindle pole Hs cellular component 418 9.05e-147
protein kinase activity Hs molecular function 418 9.05e-147
protein serine/threonine kinase activity Hs molecular function 418 9.05e-147
protein serine/threonine/tyrosine kinase activity Hs molecular function 418 9.05e-147
protein binding Hs molecular function 418 9.05e-147
ATP binding Hs molecular function 418 9.05e-147
nucleus Hs cellular component 418 9.05e-147
nucleoplasm Hs cellular component 418 9.05e-147
chromosome Hs cellular component 380 1.71e-133
cytoplasm Hs cellular component 418 9.05e-147
centrosome Hs cellular component 418 9.05e-147
centriole Hs cellular component 418 9.05e-147
microtubule organizing center Hs cellular component 418 9.05e-147
spindle Hs cellular component 418 9.05e-147
cytosol Hs cellular component 418 9.05e-147
cytoskeleton Hs cellular component 418 9.05e-147
microtubule Hs cellular component 418 9.05e-147
spindle microtubule Hs cellular component 418 9.05e-147
cilium Hs cellular component 418 9.05e-147
chromocenter Hs cellular component 365 7.40e-127
microtubule cytoskeleton Hs cellular component 418 9.05e-147
kinase activity Hs molecular function 418 9.05e-147
transferase activity Hs molecular function 418 9.05e-147
kinase binding Hs molecular function 365 7.40e-127
protein kinase binding Hs molecular function 418 9.05e-147
midbody Hs cellular component 418 9.05e-147
spindle pole centrosome Hs cellular component 418 9.05e-147
ubiquitin protein ligase binding Hs molecular function 418 9.05e-147
chromosome passenger complex Hs cellular component 418 9.05e-147
histone serine kinase activity Hs molecular function 418 9.05e-147
germinal vesicle Hs cellular component 418 9.05e-147
cell projection Hs cellular component 418 9.05e-147
axon hillock Hs cellular component 418 9.05e-147
pronucleus Hs cellular component 418 9.05e-147
metal ion binding Hs molecular function 365 7.40e-127
protein heterodimerization activity Hs molecular function 418 9.05e-147
perinuclear region of cytoplasm Hs cellular component 418 9.05e-147
spindle midzone Hs cellular component 418 9.05e-147
mitotic spindle Hs cellular component 418 9.05e-147
meiotic spindle Hs cellular component 418 9.05e-147
mitotic spindle pole Hs cellular component 418 9.05e-147
mitotic spindle midzone Hs cellular component 365 7.40e-127

GO (InterProScan)

4 results

GO Term Analysis Type e-value
protein kinase activity PANTHER molecular function 1.4E-161
ATP binding SMART molecular function 4.4E-97
protein phosphorylation SMART biological process 4.4E-97
cell cycle PANTHER biological process 1.4E-161

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