Gene Card
Best human hits
PYCR1; PYCR2; PYCR3
Unique Gene ID
Cirobu.g00012376
Gene Model ID
KH2012:KH.L37.15
Location
KhL37:299528..303778
Transcript Models and Sequences
KH2012:KH.L37.15.v1.A.SL1-1
KH2012:KH.L37.15.v1.A.SL3-1
KH2012:KH.L37.15.v1.A.SL4-1
KH2012:KH.L37.15.v2.A.SL2-1
Database | Gene ID |
---|---|
NCBI Reference Sequence | XM_002131157.4 |
cima81819
Plate: VES56_K09
cima8100696
Plate: VES72_E23
cieg055a01
Plate: R1CiGC24g04
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Pyrroline-COOH_reductase | TIGRFAM | Pyrroline-5-carboxylate reductase |
Pyrroline-COOH_reductase | Hamap | Pyrroline-5-carboxylate reductase |
NAD(P)-bd_dom_sf | SUPERFAMILY | NAD(P)-binding domain superfamily |
6-PGluconate_DH-like_C_sf | SUPERFAMILY | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily |
P5CR_dimer | Pfam | Pyrroline-5-carboxylate reductase, dimerisation domain |
P5C_Rdtase_cat_N | Pfam | Pyrroline-5-carboxylate reductase, catalytic, N-terminal |
Pyrroline-COOH_reductase | PIRSF | Pyrroline-5-carboxylate reductase |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Orthology | molecular function |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
cytosol | Blast | cellular component |
identical protein binding | Orthology | molecular function |
oxidation-reduction process | Orthology | biological process |
catalytic activity | Orthology | molecular function |
cellular biosynthetic process | Orthology | biological process |
cellular response to stress | Orthology | biological process |
response to oxidative stress | Orthology | biological process |
negative regulation of cell death | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
pyrroline-5-carboxylate reductase activity | Hs | molecular function |
protein binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
proline biosynthetic process | Hs | biological process |
cellular amino acid biosynthetic process | Hs | biological process |
oxidoreductase activity | Hs | molecular function |
cellular response to oxidative stress | Hs | biological process |
identical protein binding | Hs | molecular function |
regulation of mitochondrial membrane potential | Hs | biological process |
oxidation-reduction process | Hs | biological process |
L-proline biosynthetic process | Hs | biological process |
negative regulation of hydrogen peroxide-induced cell death | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
pyrroline-5-carboxylate reductase activity | Hs | molecular function | 328 | 2.45e-112 |
protein binding | Hs | molecular function | 327 | 8.51e-112 |
cytoplasm | Hs | cellular component | 328 | 2.45e-112 |
mitochondrion | Hs | cellular component | 328 | 2.45e-112 |
mitochondrial matrix | Hs | cellular component | 328 | 2.45e-112 |
cytosol | Hs | cellular component | 228 | 1.67e-73 |
oxidoreductase activity | Hs | molecular function | 328 | 2.45e-112 |
identical protein binding | Hs | molecular function | 327 | 8.51e-112 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
pyrroline-5-carboxylate reductase activity | PIRSF | molecular function | 6.2E-82 |
proline biosynthetic process | PIRSF | biological process | 6.2E-82 |
oxidation-reduction process | PIRSF | biological process | 6.2E-82 |