Gene Card
Best human hits
ADAMTS1; ADAMTS15; ADAMTS8
Species
Unique Gene ID
Moocci.g00006891
Gene Model ID
Moocci.CG.ELv1_2.S281638.g06891
Location
S281638:12271..22103
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
11 results
| IPR Term | Analysis | Definition |
|---|---|---|
| ADAM_Cys-rich | SMART | ADAM, cysteine-rich |
| Peptidase_M12B | Pfam | Peptidase M12B, ADAM/reprolysin |
| MetalloPept_cat_dom_sf | Gene3D | Metallopeptidase, catalytic domain superfamily |
| TSP1_rpt | Pfam | Thrombospondin type-1 (TSP1) repeat |
| TSP1_rpt | ProSiteProfiles | Thrombospondin type-1 (TSP1) repeat |
| TSP1_rpt | SMART | Thrombospondin type-1 (TSP1) repeat |
| Peptidase_M12B | ProSiteProfiles | Peptidase M12B, ADAM/reprolysin |
| TSP1_rpt_sf | Gene3D | Thrombospondin type-1 (TSP1) repeat superfamily |
| TSP1_rpt_sf | SUPERFAMILY | Thrombospondin type-1 (TSP1) repeat superfamily |
| Peptidase_M12B_N | Pfam | Peptidase M12B, propeptide |
| ADAM_spacer1 | Pfam | ADAM-TS Spacer 1 |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
33 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| kidney development | Hs | biological process |
| endopeptidase activity | Hs | molecular function |
| metalloendopeptidase activity | Hs | molecular function |
| integrin binding | Hs | molecular function |
| extracellular region | Hs | cellular component |
| proteinaceous extracellular matrix | Hs | cellular component |
| basement membrane | Hs | cellular component |
| extracellular space | Hs | cellular component |
| proteolysis | Hs | biological process |
| integrin-mediated signaling pathway | Hs | biological process |
| heparin binding | Hs | molecular function |
| peptidase activity | Hs | molecular function |
| metallopeptidase activity | Hs | molecular function |
| zinc ion binding | Hs | molecular function |
| negative regulation of cell proliferation | Hs | biological process |
| low-affinity phosphate transmembrane transporter activity | Hs | molecular function |
| cell surface | Hs | cellular component |
| membrane | Hs | cellular component |
| integral component of membrane | Hs | cellular component |
| hydrolase activity | Hs | molecular function |
| extracellular matrix | Hs | cellular component |
| cytoplasmic vesicle | Hs | cellular component |
| phosphate ion transmembrane transport | Hs | biological process |
| metal ion binding | Hs | molecular function |
| extracellular matrix binding | Hs | molecular function |
| heart trabecula formation | Hs | biological process |
| skeletal system development | Hs | biological process |
| protease binding | Hs | molecular function |
| protein binding | Hs | molecular function |
| endoplasmic reticulum lumen | Hs | cellular component |
| nuclear speck | Hs | cellular component |
| protein O-linked fucosylation | Hs | biological process |
| defense response to bacterium | Hs | biological process |
GO (Blast)
20 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| endopeptidase activity | Hs | molecular function | 704 | 0.0 |
| metalloendopeptidase activity | Hs | molecular function | 704 | 0.0 |
| integrin binding | Hs | molecular function | 628 | 0.0 |
| extracellular region | Hs | cellular component | 704 | 0.0 |
| proteinaceous extracellular matrix | Hs | cellular component | 704 | 0.0 |
| basement membrane | Hs | cellular component | 671 | 0.0 |
| extracellular space | Hs | cellular component | 704 | 0.0 |
| heparin binding | Hs | molecular function | 704 | 0.0 |
| peptidase activity | Hs | molecular function | 704 | 0.0 |
| metallopeptidase activity | Hs | molecular function | 704 | 0.0 |
| zinc ion binding | Hs | molecular function | 704 | 0.0 |
| low-affinity phosphate transmembrane transporter activity | Hs | molecular function | 628 | 0.0 |
| cell surface | Hs | cellular component | 704 | 0.0 |
| membrane | Hs | cellular component | 671 | 0.0 |
| integral component of membrane | Hs | cellular component | 671 | 0.0 |
| hydrolase activity | Hs | molecular function | 704 | 0.0 |
| extracellular matrix | Hs | cellular component | 628 | 0.0 |
| cytoplasmic vesicle | Hs | cellular component | 671 | 0.0 |
| metal ion binding | Hs | molecular function | 704 | 0.0 |
| extracellular matrix binding | Hs | molecular function | 704 | 0.0 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| metalloendopeptidase activity | Pfam | molecular function | 9.3E-24 |
| proteolysis | Pfam | biological process | 9.3E-24 |
| metallopeptidase activity | Gene3D | molecular function | 3.1E-86 |
