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GENE CARD

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Gene Card

Best human hits

NKX2-3; NKX2-5; NKX2-6

Species

M.occidentalis

Unique Gene ID

Moocci.g00008813

Gene Model ID

Moocci.CG.ELv1_2.S332293.g08813

Location

S332293:13775..15931

Transcript Models and Sequences

  Moocci.CG.ELv1_2.S332293.g08813.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
Homeobox-like_sf SUPERFAMILY Homeobox-like domain superfamily
Homeobox_dom Pfam Homeobox domain
Homeobox_CS ProSitePatterns Homeobox, conserved site
Homeobox_dom SMART Homeobox domain
Homeobox_dom ProSiteProfiles Homeobox domain
Homeobox_dom CDD Homeobox domain
NKX-2.5 PANTHER Homeobox protein NKX-2.5
Homeobox_metazoa PRINTS Homeobox domain, metazoa

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

85 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
RNA polymerase II transcription cofactor activity Hs molecular function
transcriptional activator activity, RNA polymerase II transcription factor binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
vasculogenesis Hs biological process
heart looping Hs biological process
heart morphogenesis Hs biological process
outflow tract morphogenesis Hs biological process
cardiac conduction system development Hs biological process
cardiac ventricle morphogenesis Hs biological process
cardiac ventricle formation Hs biological process
ventricular trabecula myocardium morphogenesis Hs biological process
proepicardium development Hs biological process
DNA binding Hs molecular function
chromatin binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
transcription factor complex Hs cellular component
cytoplasm Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription from RNA polymerase II promoter Hs biological process
triglyceride metabolic process Hs biological process
immune response Hs biological process
multicellular organism development Hs biological process
heart development Hs biological process
adult heart development Hs biological process
transcription factor binding Hs molecular function
positive regulation of cell proliferation Hs biological process
post-embryonic development Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of cardiac muscle cell apoptotic process Hs biological process
positive regulation of transcription via serum response element binding Hs biological process
serum response element binding Hs molecular function
hypothalamus development Hs biological process
hemopoiesis Hs biological process
cell differentiation Hs biological process
B cell differentiation Hs biological process
macrophage differentiation Hs biological process
BMP signaling pathway Hs biological process
thyroid gland development Hs biological process
macromolecular complex Hs cellular component
protein-DNA complex Hs cellular component
embryonic heart tube development Hs biological process
regulation of cell proliferation Hs biological process
protein homodimerization activity Hs molecular function
negative regulation of apoptotic process Hs biological process
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
sarcomere organization Hs biological process
positive regulation of neuron differentiation Hs biological process
positive regulation of heart contraction Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
protein heterodimerization activity Hs molecular function
digestive tract development Hs biological process
post-embryonic digestive tract morphogenesis Hs biological process
cardiac muscle tissue development Hs biological process
leukocyte migration Hs biological process
ventricular cardiac myofibril assembly Hs biological process
cardiac muscle cell differentiation Hs biological process
cardiac muscle tissue morphogenesis Hs biological process
atrial cardiac muscle cell development Hs biological process
ventricular cardiac muscle cell development Hs biological process
regulation of cardiac muscle contraction Hs biological process
pharyngeal system development Hs biological process
cardiac muscle cell proliferation Hs biological process
regulation of cardiac muscle cell proliferation Hs biological process
heart contraction Hs biological process
cardiac muscle contraction Hs biological process
canonical Wnt signaling pathway Hs biological process
positive regulation of transcription initiation from RNA polymerase II promoter Hs biological process
heart trabecula formation Hs biological process
embryonic heart tube left/right pattern formation Hs biological process
cardiovascular system development Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
RNA polymerase II transcription factor complex Hs cellular component
regulation of cardiac conduction Hs biological process

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 162 1.36e-47
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 179 3.16e-54
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 162 1.36e-47
RNA polymerase II transcription cofactor activity Hs molecular function 162 1.36e-47
transcriptional activator activity, RNA polymerase II transcription factor binding Hs molecular function 162 1.36e-47
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 162 1.36e-47
DNA binding Hs molecular function 179 3.16e-54
chromatin binding Hs molecular function 162 1.36e-47
transcription factor activity, sequence-specific DNA binding Hs molecular function 179 3.16e-54
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 162 1.36e-47
protein binding Hs molecular function 162 1.36e-47
nucleus Hs cellular component 179 3.16e-54
transcription factor complex Hs cellular component 162 1.36e-47
cytoplasm Hs cellular component 162 1.36e-47
transcription factor binding Hs molecular function 162 1.36e-47
serum response element binding Hs molecular function 162 1.36e-47
macromolecular complex Hs cellular component 162 1.36e-47
protein-DNA complex Hs cellular component 162 1.36e-47
protein homodimerization activity Hs molecular function 162 1.36e-47
sequence-specific DNA binding Hs molecular function 179 3.16e-54
transcription regulatory region DNA binding Hs molecular function 162 1.36e-47
protein heterodimerization activity Hs molecular function 162 1.36e-47
RNA polymerase II transcription factor complex Hs cellular component 162 1.36e-47

GO (InterProScan)

8 results

GO Term Analysis Type e-value
DNA binding SMART molecular function 2.7E-24
transcription factor activity, sequence-specific DNA binding PANTHER molecular function 1.7E-78
regulation of transcription, DNA-templated ProSitePatterns biological process
regulation of transcription from RNA polymerase II promoter PANTHER biological process 1.7E-78
heart development PANTHER biological process 1.7E-78
sequence-specific DNA binding ProSitePatterns molecular function
cardiac muscle contraction PANTHER biological process 1.7E-78
regulation of cardiac conduction PANTHER biological process 1.7E-78

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