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GENE CARD

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Gene Card

Best human hits

PAH; TPH1; TPH2

Species

M.occidentalis

Unique Gene ID

Moocci.g00011849

Gene Model ID

Moocci.CG.ELv1_2.S402302.g11849

Location

S402302:12124..23402

Transcript Models and Sequences

  Moocci.CG.ELv1_2.S402302.g11849.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Aromatic-AA_hydroxylase_C PRINTS Aromatic amino acid hydroxylase, C-terminal
ArAA_hydroxylase_Fe/CU_BS ProSitePatterns Aromatic amino acid hydroxylase, iron/copper binding site
ArAA_hydroxylase PANTHER Aromatic amino acid hydroxylase
Aromatic-AA_hydroxylase_C Pfam Aromatic amino acid hydroxylase, C-terminal
Aromatic-AA_hydroxylase_C ProSiteProfiles Aromatic amino acid hydroxylase, C-terminal
Aro-AA_hydroxylase_C_sf SUPERFAMILY Aromatic amino acid monoxygenase, C-terminal domain superfamily
ArAA_hydroxylase_sf Gene3D Aromatic amino acid hydroxylase superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

29 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
catalytic activity Hs molecular function
monooxygenase activity Hs molecular function
phenylalanine 4-monooxygenase activity Hs molecular function
tryptophan 5-monooxygenase activity Hs molecular function
iron ion binding Hs molecular function
cytoplasm Hs cellular component
cytosol Hs cellular component
L-phenylalanine catabolic process Hs biological process
circadian rhythm Hs biological process
metabolic process Hs biological process
cellular amino acid biosynthetic process Hs biological process
aromatic amino acid family metabolic process Hs biological process
response to activity Hs biological process
oxidoreductase activity Hs molecular function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen Hs molecular function
negative regulation of ossification Hs biological process
response to nutrient levels Hs biological process
neurotransmitter biosynthetic process Hs biological process
catecholamine biosynthetic process Hs biological process
serotonin biosynthetic process Hs biological process
neuron projection Hs cellular component
response to estrogen Hs biological process
positive regulation of fat cell differentiation Hs biological process
bone remodeling Hs biological process
metal ion binding Hs molecular function
response to glucocorticoid Hs biological process
response to calcium ion Hs biological process
oxidation-reduction process Hs biological process
extracellular exosome Hs cellular component

GO (Blast)

12 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
catalytic activity Hs molecular function 384 1.44e-133
monooxygenase activity Hs molecular function 384 1.44e-133
phenylalanine 4-monooxygenase activity Hs molecular function 384 1.44e-133
tryptophan 5-monooxygenase activity Hs molecular function 343 5.00e-117
iron ion binding Hs molecular function 384 1.44e-133
cytoplasm Hs cellular component 338 1.75e-115
cytosol Hs cellular component 384 1.44e-133
oxidoreductase activity Hs molecular function 384 1.44e-133
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen Hs molecular function 384 1.44e-133
neuron projection Hs cellular component 343 5.00e-117
metal ion binding Hs molecular function 384 1.44e-133
extracellular exosome Hs cellular component 384 1.44e-133

GO (InterProScan)

5 results

GO Term Analysis Type e-value
monooxygenase activity PANTHER molecular function 1.2E-139
iron ion binding PANTHER molecular function 1.2E-139
aromatic amino acid family metabolic process PANTHER biological process 1.2E-139
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen Pfam molecular function 1.6E-136
oxidation-reduction process PANTHER biological process 1.2E-139