Gene Card
Best human hits
LRP6; SORL1
Species
Unique Gene ID
Moocci.g00012435
Gene Model ID
Moocci.CG.ELv1_2.S414058.g12435
Location
S414058:15425..18022
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
11 results
| IPR Term | Analysis | Definition |
|---|---|---|
| EGF-like_dom | Pfam | EGF-like domain |
| LDLR_class-A_CS | ProSitePatterns | Low-density lipoprotein (LDL) receptor class A, conserved site |
| EGF-like_dom | ProSiteProfiles | EGF-like domain |
| LDrepeatLR_classA_rpt | CDD | Low-density lipoprotein (LDL) receptor class A repeat |
| LDrepeatLR_classA_rpt | ProSiteProfiles | Low-density lipoprotein (LDL) receptor class A repeat |
| LDrepeatLR_classA_rpt | Pfam | Low-density lipoprotein (LDL) receptor class A repeat |
| EGF-like_dom | SMART | EGF-like domain |
| LDrepeatLR_classA_rpt | PRINTS | Low-density lipoprotein (LDL) receptor class A repeat |
| LDrepeatLR_classA_rpt | SMART | Low-density lipoprotein (LDL) receptor class A repeat |
| LDL_receptor-like_sf | SUPERFAMILY | LDL receptor-like superfamily |
| EGF-like_CS | ProSitePatterns | EGF-like, conserved site |
| GO Term | Annotation Origin | Type |
|---|
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
45 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 71.6 | 1.67e-13 |
| amyloid-beta binding | Hs | molecular function | 71.6 | 1.67e-13 |
| transmembrane signaling receptor activity | Hs | molecular function | 71.6 | 1.67e-13 |
| low-density lipoprotein receptor activity | Hs | molecular function | 73.6 | 3.54e-14 |
| receptor binding | Hs | molecular function | 73.6 | 3.54e-14 |
| frizzled binding | Hs | molecular function | 73.6 | 3.54e-14 |
| protein binding | Hs | molecular function | 73.6 | 3.54e-14 |
| extracellular region | Hs | cellular component | 73.6 | 3.54e-14 |
| extracellular space | Hs | cellular component | 71.6 | 1.67e-13 |
| nuclear envelope lumen | Hs | cellular component | 71.6 | 1.67e-13 |
| endosome | Hs | cellular component | 71.6 | 1.67e-13 |
| early endosome | Hs | cellular component | 73.6 | 3.54e-14 |
| endoplasmic reticulum | Hs | cellular component | 73.6 | 3.54e-14 |
| Golgi apparatus | Hs | cellular component | 73.6 | 3.54e-14 |
| trans-Golgi network | Hs | cellular component | 71.6 | 1.67e-13 |
| plasma membrane | Hs | cellular component | 73.6 | 3.54e-14 |
| integral component of plasma membrane | Hs | cellular component | 71.6 | 1.67e-13 |
| caveola | Hs | cellular component | 73.6 | 3.54e-14 |
| cell surface | Hs | cellular component | 73.6 | 3.54e-14 |
| endosome membrane | Hs | cellular component | 71.6 | 1.67e-13 |
| membrane | Hs | cellular component | 73.6 | 3.54e-14 |
| integral component of membrane | Hs | cellular component | 73.6 | 3.54e-14 |
| Wnt-protein binding | Hs | molecular function | 73.6 | 3.54e-14 |
| kinase inhibitor activity | Hs | molecular function | 73.6 | 3.54e-14 |
| toxin transporter activity | Hs | molecular function | 73.6 | 3.54e-14 |
| low-density lipoprotein particle binding | Hs | molecular function | 71.6 | 1.67e-13 |
| ADP-ribosylation factor binding | Hs | molecular function | 71.6 | 1.67e-13 |
| cytoplasmic vesicle | Hs | cellular component | 73.6 | 3.54e-14 |
| early endosome membrane | Hs | cellular component | 73.6 | 3.54e-14 |
| Golgi cisterna | Hs | cellular component | 71.6 | 1.67e-13 |
| apolipoprotein binding | Hs | molecular function | 73.6 | 3.54e-14 |
| low-density lipoprotein particle | Hs | cellular component | 71.6 | 1.67e-13 |
| identical protein binding | Hs | molecular function | 73.6 | 3.54e-14 |
| protein homodimerization activity | Hs | molecular function | 73.6 | 3.54e-14 |
| Wnt-activated receptor activity | Hs | molecular function | 73.6 | 3.54e-14 |
| neuronal cell body | Hs | cellular component | 73.6 | 3.54e-14 |
| receptor complex | Hs | cellular component | 73.6 | 3.54e-14 |
| membrane raft | Hs | cellular component | 73.6 | 3.54e-14 |
| synapse | Hs | cellular component | 73.6 | 3.54e-14 |
| recycling endosome | Hs | cellular component | 71.6 | 1.67e-13 |
| extracellular exosome | Hs | cellular component | 71.6 | 1.67e-13 |
| coreceptor activity involved in Wnt signaling pathway | Hs | molecular function | 73.6 | 3.54e-14 |
| coreceptor activity involved in canonical Wnt signaling pathway | Hs | molecular function | 73.6 | 3.54e-14 |
| Wnt-Frizzled-LRP5/6 complex | Hs | cellular component | 73.6 | 3.54e-14 |
| Wnt signalosome | Hs | cellular component | 73.6 | 3.54e-14 |
GO (InterProScan)
1 result
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | PRINTS | molecular function | 4.9E-11 |
