Gene Card
Best human hits
BMPR1A; BMPR1B; TGFBR1
Species
Unique Gene ID
Moocci.g00013453
Gene Model ID
Moocci.CG.ELv1_2.S433346.g13453
Location
S433346:3448..19595
Transcript Models and Sequences
n/a
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Click here to see the tree inference method
InterPro
11 results
| IPR Term | Analysis | Definition |
|---|---|---|
| TGFB_receptor | PANTHER | Ser/Thr protein kinase, TGFB receptor |
| Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
| Prot_kinase_dom | SMART | Protein kinase domain |
| Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
| Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
| GS_dom | SMART | GS domain |
| GS_dom | Pfam | GS domain |
| GS_dom | ProSiteProfiles | GS domain |
| Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
| Activin_recp | Pfam | Activin types I and II receptor domain |
| Prot_kinase_dom | Pfam | Protein kinase domain |
| GO Term | Annotation Origin | Type |
|---|
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
40 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 405 | 4.19e-135 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 387 | 5.56e-128 |
| protein kinase activity | Hs | molecular function | 405 | 4.19e-135 |
| protein serine/threonine kinase activity | Hs | molecular function | 405 | 4.19e-135 |
| transmembrane receptor protein serine/threonine kinase activity | Hs | molecular function | 405 | 4.19e-135 |
| signal transducer, downstream of receptor, with serine/threonine kinase activity | Hs | molecular function | 405 | 4.19e-135 |
| transforming growth factor beta-activated receptor activity | Hs | molecular function | 352 | 1.04e-114 |
| transforming growth factor beta receptor activity, type I | Hs | molecular function | 405 | 4.19e-135 |
| signal transducer activity, downstream of receptor | Hs | molecular function | 352 | 1.04e-114 |
| receptor binding | Hs | molecular function | 352 | 1.04e-114 |
| type II transforming growth factor beta receptor binding | Hs | molecular function | 352 | 1.04e-114 |
| protein binding | Hs | molecular function | 405 | 4.19e-135 |
| ATP binding | Hs | molecular function | 405 | 4.19e-135 |
| cell | Hs | cellular component | 352 | 1.04e-114 |
| endosome | Hs | cellular component | 352 | 1.04e-114 |
| plasma membrane | Hs | cellular component | 405 | 4.19e-135 |
| integral component of plasma membrane | Hs | cellular component | 405 | 4.19e-135 |
| caveola | Hs | cellular component | 387 | 5.56e-128 |
| bicellular tight junction | Hs | cellular component | 352 | 1.04e-114 |
| external side of plasma membrane | Hs | cellular component | 387 | 5.56e-128 |
| cell surface | Hs | cellular component | 352 | 1.04e-114 |
| membrane | Hs | cellular component | 405 | 4.19e-135 |
| integral component of membrane | Hs | cellular component | 405 | 4.19e-135 |
| kinase activity | Hs | molecular function | 405 | 4.19e-135 |
| transferase activity | Hs | molecular function | 405 | 4.19e-135 |
| growth factor binding | Hs | molecular function | 352 | 1.04e-114 |
| cell junction | Hs | cellular component | 352 | 1.04e-114 |
| dendrite | Hs | cellular component | 405 | 4.19e-135 |
| protein homodimerization activity | Hs | molecular function | 387 | 5.56e-128 |
| neuronal cell body | Hs | cellular component | 405 | 4.19e-135 |
| intracellular membrane-bounded organelle | Hs | cellular component | 352 | 1.04e-114 |
| receptor complex | Hs | cellular component | 405 | 4.19e-135 |
| membrane raft | Hs | cellular component | 352 | 1.04e-114 |
| SMAD binding | Hs | molecular function | 405 | 4.19e-135 |
| metal ion binding | Hs | molecular function | 405 | 4.19e-135 |
| transforming growth factor beta binding | Hs | molecular function | 352 | 1.04e-114 |
| transforming growth factor beta receptor complex | Hs | cellular component | 352 | 1.04e-114 |
| I-SMAD binding | Hs | molecular function | 352 | 1.04e-114 |
| BMP receptor activity | Hs | molecular function | 387 | 5.56e-128 |
| HFE-transferrin receptor complex | Hs | cellular component | 405 | 4.19e-135 |
GO (InterProScan)
7 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein kinase activity | Pfam | molecular function | 3.5E-28 |
| transmembrane receptor protein serine/threonine kinase activity | Pfam | molecular function | 9.2E-10 |
| signal transducer, downstream of receptor, with serine/threonine kinase activity | PANTHER | molecular function | 5.4E-160 |
| ATP binding | PANTHER | molecular function | 5.4E-160 |
| protein phosphorylation | Pfam | biological process | 3.5E-28 |
| transmembrane receptor protein serine/threonine kinase signaling pathway | PANTHER | biological process | 5.4E-160 |
| membrane | PANTHER | cellular component | 5.4E-160 |
