Gene Card
Best human hits
EIF2S1
Species
Unique Gene ID
Moocci.g00014996
Gene Model ID
Moocci.CG.ELv1_2.S457226.g14996
Location
S457226:7764..11008
Transcript Models and Sequences
Moocci.CG.ELv1_2.S457226.g14996.01.t
Moocci.CG.ELv1_2.S457226.g14996.02.t
Moocci.CG.ELv1_2.S457226.g14996.03.t
n/a
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Click here to see the tree inference method
InterPro
11 results
| IPR Term | Analysis | Definition |
|---|---|---|
| TIF_2_asu | PANTHER | Translation initiation factor 2, alpha subunit |
| S1_domain | Pfam | S1 domain |
| NA-bd_OB-fold | SUPERFAMILY | Nucleic acid-binding, OB-fold |
| TIF_2_asu | Pfam | Translation initiation factor 2, alpha subunit |
| TIF2_asu_C | Gene3D | Translation initiation factor 2, alpha subunit, C-terminal |
| TIF2_asu_C | SUPERFAMILY | Translation initiation factor 2, alpha subunit, C-terminal |
| TIF2_asu_middle_sf | Gene3D | Translation initiation factor 2, alpha subunit, middle domain superfamily |
| TIF2_asu_middle_sf | SUPERFAMILY | Translation initiation factor 2, alpha subunit, middle domain superfamily |
| S1_domain | ProSiteProfiles | S1 domain |
| S1_dom | SMART | RNA-binding domain, S1 |
| Med9 | Pfam | Mediator of RNA polymerase II transcription subunit 9 |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
31 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| nucleic acid binding | Hs | molecular function |
| RNA binding | Hs | molecular function |
| translation initiation factor activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| cytosol | Hs | cellular component |
| ribosome | Hs | cellular component |
| polysome | Hs | cellular component |
| eukaryotic translation initiation factor 2 complex | Hs | cellular component |
| eukaryotic translation initiation factor 2B complex | Hs | cellular component |
| translation | Hs | biological process |
| translational initiation | Hs | biological process |
| regulation of translation | Hs | biological process |
| aging | Hs | biological process |
| cytoplasmic stress granule | Hs | cellular component |
| membrane | Hs | cellular component |
| eukaryotic 48S preinitiation complex | Hs | cellular component |
| cellular response to amino acid starvation | Hs | biological process |
| cellular response to heat | Hs | biological process |
| cellular response to UV | Hs | biological process |
| response to endoplasmic reticulum stress | Hs | biological process |
| PERK-mediated unfolded protein response | Hs | biological process |
| ribosome binding | Hs | molecular function |
| multi-eIF complex | Hs | cellular component |
| translation initiation ternary complex | Hs | cellular component |
| protein autophosphorylation | Hs | biological process |
| transmembrane transport | Hs | biological process |
| extracellular exosome | Hs | cellular component |
| glial limiting end-foot | Hs | cellular component |
| positive regulation of neuron death | Hs | biological process |
GO (Blast)
19 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleic acid binding | Hs | molecular function | 399 | 4.49e-140 |
| RNA binding | Hs | molecular function | 399 | 4.49e-140 |
| translation initiation factor activity | Hs | molecular function | 399 | 4.49e-140 |
| protein binding | Hs | molecular function | 399 | 4.49e-140 |
| nucleus | Hs | cellular component | 399 | 4.49e-140 |
| cytoplasm | Hs | cellular component | 399 | 4.49e-140 |
| cytosol | Hs | cellular component | 399 | 4.49e-140 |
| ribosome | Hs | cellular component | 399 | 4.49e-140 |
| polysome | Hs | cellular component | 399 | 4.49e-140 |
| eukaryotic translation initiation factor 2 complex | Hs | cellular component | 399 | 4.49e-140 |
| eukaryotic translation initiation factor 2B complex | Hs | cellular component | 399 | 4.49e-140 |
| cytoplasmic stress granule | Hs | cellular component | 399 | 4.49e-140 |
| membrane | Hs | cellular component | 399 | 4.49e-140 |
| eukaryotic 48S preinitiation complex | Hs | cellular component | 399 | 4.49e-140 |
| ribosome binding | Hs | molecular function | 399 | 4.49e-140 |
| multi-eIF complex | Hs | cellular component | 399 | 4.49e-140 |
| translation initiation ternary complex | Hs | cellular component | 399 | 4.49e-140 |
| extracellular exosome | Hs | cellular component | 399 | 4.49e-140 |
| glial limiting end-foot | Hs | cellular component | 399 | 4.49e-140 |
GO (InterProScan)
6 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| nucleic acid binding | Pfam | molecular function | 3.0E-15 |
| RNA binding | PANTHER | molecular function | 7.6E-133 |
| translation initiation factor activity | PANTHER | molecular function | 7.6E-133 |
| RNA polymerase II transcription cofactor activity | Pfam | molecular function | 1.9E-10 |
| regulation of transcription from RNA polymerase II promoter | Pfam | biological process | 1.9E-10 |
| mediator complex | Pfam | cellular component | 1.9E-10 |
