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GENE CARD

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Gene Card

Best human hits

LRP5; LRP6

Species

M.occidentalis

Unique Gene ID

Moocci.g00017382

Gene Model ID

Moocci.CG.ELv1_2.S484557.g17382

Location

S484557:22002..28588

Transcript Models and Sequences

  Moocci.CG.ELv1_2.S484557.g17382.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
LDrepeatLR_classA_rpt ProSiteProfiles Low-density lipoprotein (LDL) receptor class A repeat
LDL_receptor-like_sf SUPERFAMILY LDL receptor-like superfamily
LDLR_classB_rpt ProSiteProfiles LDLR class B repeat
LDrepeatLR_classA_rpt CDD Low-density lipoprotein (LDL) receptor class A repeat
LDLR_classB_rpt Pfam LDLR class B repeat
LDLR_class-A_CS ProSitePatterns Low-density lipoprotein (LDL) receptor class A, conserved site
LDrepeatLR_classA_rpt Pfam Low-density lipoprotein (LDL) receptor class A repeat
6-blade_b-propeller_TolB-like Gene3D Six-bladed beta-propeller, TolB-like
LDrepeatLR_classA_rpt SMART Low-density lipoprotein (LDL) receptor class A repeat
LDLR_classB_rpt SMART LDLR class B repeat
EGF-like_dom SMART EGF-like domain
LDrepeatLR_classA_rpt PRINTS Low-density lipoprotein (LDL) receptor class A repeat

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

99 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
gastrulation with mouth forming second Hs biological process
neural tube closure Hs biological process
negative regulation of protein phosphorylation Hs biological process
vasculature development Hs biological process
osteoblast development Hs biological process
pericardium morphogenesis Hs biological process
low-density lipoprotein receptor activity Hs molecular function
receptor binding Hs molecular function
frizzled binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
mitochondrion Hs cellular component
early endosome Hs cellular component
endoplasmic reticulum Hs cellular component
Golgi apparatus Hs cellular component
plasma membrane Hs cellular component
caveola Hs cellular component
glucose catabolic process Hs biological process
regulation of transcription, DNA-templated Hs biological process
negative regulation of protein kinase activity Hs biological process
endocytosis Hs biological process
positive regulation of cytosolic calcium ion concentration Hs biological process
chemical synaptic transmission Hs biological process
multicellular organism development Hs biological process
cholesterol metabolic process Hs biological process
regulation of blood pressure Hs biological process
positive regulation of cell proliferation Hs biological process
response to radiation Hs biological process
embryonic pattern specification Hs biological process
anterior/posterior pattern specification Hs biological process
cell surface Hs cellular component
neural crest formation Hs biological process
neural crest cell differentiation Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
Wnt signaling pathway Hs biological process
Wnt-protein binding Hs molecular function
kinase inhibitor activity Hs molecular function
toxin transporter activity Hs molecular function
cerebellum morphogenesis Hs biological process
thalamus development Hs biological process
cerebral cortex development Hs biological process
midbrain-hindbrain boundary development Hs biological process
cytoplasmic vesicle Hs cellular component
early endosome membrane Hs cellular component
apolipoprotein binding Hs molecular function
somatic stem cell population maintenance Hs biological process
limb morphogenesis Hs biological process
cell migration involved in gastrulation Hs biological process
cholesterol homeostasis Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
Wnt-activated receptor activity Hs molecular function
regulation of apoptotic process Hs biological process
neuronal cell body Hs cellular component
receptor complex Hs cellular component
response to peptide hormone Hs biological process
Wnt signaling pathway involved in dorsal/ventral axis specification Hs biological process
membrane raft Hs cellular component
synapse Hs cellular component
positive regulation of fat cell differentiation Hs biological process
negative regulation of osteoblast differentiation Hs biological process
positive regulation of cell cycle Hs biological process
positive regulation of mitotic nuclear division Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
bone remodeling Hs biological process
regulation of bone remodeling Hs biological process
positive regulation of sequence-specific DNA binding transcription factor activity Hs biological process
palate development Hs biological process
convergent extension Hs biological process
anatomical structure regression Hs biological process
retina morphogenesis in camera-type eye Hs biological process
embryonic retina morphogenesis in camera-type eye Hs biological process
canonical Wnt signaling pathway Hs biological process
face morphogenesis Hs biological process
bone development Hs biological process
bone morphogenesis Hs biological process
adipose tissue development Hs biological process
regulation of canonical Wnt signaling pathway Hs biological process
regulation of insulin secretion involved in cellular response to glucose stimulus Hs biological process
retinal blood vessel morphogenesis Hs biological process
dopaminergic neuron differentiation Hs biological process
negative regulation of protein serine/threonine kinase activity Hs biological process
coreceptor activity involved in Wnt signaling pathway Hs molecular function
protein localization to plasma membrane Hs biological process
primitive streak formation Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
receptor-mediated endocytosis involved in cholesterol transport Hs biological process
Wnt signaling pathway involved in somitogenesis Hs biological process
axis elongation involved in somitogenesis Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
cell-cell adhesion Hs biological process
toxin transport Hs biological process
apoptotic process involved in blood vessel morphogenesis Hs biological process
coreceptor activity involved in canonical Wnt signaling pathway Hs molecular function
Wnt-Frizzled-LRP5/6 complex Hs cellular component
Wnt signalosome Hs cellular component
positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification Hs biological process

GO (Blast)

31 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
low-density lipoprotein receptor activity Hs molecular function 645 0.0
receptor binding Hs molecular function 645 0.0
frizzled binding Hs molecular function 645 0.0
protein binding Hs molecular function 645 0.0
extracellular region Hs cellular component 645 0.0
mitochondrion Hs cellular component 616 0.0
early endosome Hs cellular component 645 0.0
endoplasmic reticulum Hs cellular component 645 0.0
Golgi apparatus Hs cellular component 645 0.0
plasma membrane Hs cellular component 645 0.0
caveola Hs cellular component 645 0.0
cell surface Hs cellular component 645 0.0
membrane Hs cellular component 645 0.0
integral component of membrane Hs cellular component 645 0.0
Wnt-protein binding Hs molecular function 645 0.0
kinase inhibitor activity Hs molecular function 645 0.0
toxin transporter activity Hs molecular function 645 0.0
cytoplasmic vesicle Hs cellular component 645 0.0
early endosome membrane Hs cellular component 645 0.0
apolipoprotein binding Hs molecular function 645 0.0
identical protein binding Hs molecular function 645 0.0
protein homodimerization activity Hs molecular function 645 0.0
Wnt-activated receptor activity Hs molecular function 645 0.0
neuronal cell body Hs cellular component 645 0.0
receptor complex Hs cellular component 645 0.0
membrane raft Hs cellular component 645 0.0
synapse Hs cellular component 645 0.0
coreceptor activity involved in Wnt signaling pathway Hs molecular function 645 0.0
coreceptor activity involved in canonical Wnt signaling pathway Hs molecular function 645 0.0
Wnt-Frizzled-LRP5/6 complex Hs cellular component 645 0.0
Wnt signalosome Hs cellular component 645 0.0

GO (InterProScan)

1 result

GO Term Analysis Type e-value
protein binding PRINTS molecular function 6.7E-20

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