Gene Card
Best human hits
SMG5; SMG6; SMG7
Species
Unique Gene ID
Moocci.g00023568
Gene Model ID
Moocci.CG.ELv1_2.S586795.g23568
Location
S586795:995..12208
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
TPR-like_helical_dom_sf | SUPERFAMILY | Tetratricopeptide-like helical domain superfamily |
EST1 | Pfam | Telomerase activating protein Est1 |
DNA/RNA-bd_Est1-type | Pfam | DNA/RNA-binding domain, Est1-type |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | Hs | biological process |
ribonuclease activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
telomerase holoenzyme complex | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
mRNA export from nucleus | Hs | biological process |
ubiquitin protein ligase binding | Hs | molecular function |
regulation of telomere maintenance via telomerase | Hs | biological process |
regulation of dephosphorylation | Hs | biological process |
telomeric DNA binding | Hs | molecular function |
histone deacetylase binding | Hs | molecular function |
ribonucleoprotein complex binding | Hs | molecular function |
regulation of RNA stability | Hs | biological process |
protein phosphatase 2A binding | Hs | molecular function |
telomerase RNA binding | Hs | molecular function |
DNA polymerase binding | Hs | molecular function |
RNA phosphodiester bond hydrolysis | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
telomerase catalytic core complex | Hs | cellular component | 54.3 | 3.32e-07 |
chromosome, telomeric region | Hs | cellular component | 54.3 | 3.32e-07 |
DNA binding | Hs | molecular function | 54.3 | 3.32e-07 |
RNA binding | Hs | molecular function | 54.3 | 3.32e-07 |
nuclease activity | Hs | molecular function | 54.3 | 3.32e-07 |
endonuclease activity | Hs | molecular function | 54.3 | 3.32e-07 |
endoribonuclease activity | Hs | molecular function | 54.3 | 3.32e-07 |
ribonuclease activity | Hs | molecular function | 185 | 5.43e-48 |
protein binding | Hs | molecular function | 185 | 5.43e-48 |
nucleus | Hs | cellular component | 185 | 5.43e-48 |
chromosome | Hs | cellular component | 54.3 | 3.32e-07 |
telomerase holoenzyme complex | Hs | cellular component | 185 | 5.43e-48 |
nucleolus | Hs | cellular component | 54.3 | 3.32e-07 |
cytoplasm | Hs | cellular component | 185 | 5.43e-48 |
cytosol | Hs | cellular component | 185 | 5.43e-48 |
hydrolase activity | Hs | molecular function | 54.3 | 3.32e-07 |
ubiquitin protein ligase binding | Hs | molecular function | 185 | 5.43e-48 |
exon-exon junction complex | Hs | cellular component | 54.3 | 3.32e-07 |
telomeric DNA binding | Hs | molecular function | 185 | 5.43e-48 |
histone deacetylase binding | Hs | molecular function | 185 | 5.43e-48 |
ribonucleoprotein complex binding | Hs | molecular function | 185 | 5.43e-48 |
intermediate filament cytoskeleton | Hs | cellular component | 45.8 | 1.37e-04 |
metal ion binding | Hs | molecular function | 54.3 | 3.32e-07 |
protein phosphatase 2A binding | Hs | molecular function | 185 | 5.43e-48 |
telomerase RNA binding | Hs | molecular function | 185 | 5.43e-48 |
DNA polymerase binding | Hs | molecular function | 185 | 5.43e-48 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | SUPERFAMILY | molecular function | 1.18E-38 |