Gene Card
Best human hits
MGMT
Species
Unique Gene ID
Moocci.g00027638
Gene Model ID
Moocci.CG.ELv1_2.S632562.g27638
Location
S632562:11628..12193
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
7 results
| IPR Term | Analysis | Definition |
|---|---|---|
| MethylDNA_cys_MeTrfase_AS | ProSitePatterns | Methylated-DNA-[protein]-cysteine S-methyltransferase, active site |
| WH-like_DNA-bd_sf | Gene3D | Winged helix-like DNA-binding domain superfamily |
| MethylDNA_cys_MeTrfase_DNA-bd | TIGRFAM | Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding |
| MethylDNA_cys_MeTrfase_DNA-bd | Pfam | Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding |
| MethylDNA_cys_MeTrfase_DNAb | SUPERFAMILY | Methylated DNA-protein cysteine methyltransferase, DNA binding domain |
| MethylDNA_cys_MeTrfase_DNA-bd | CDD | Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding |
| MGMT_N_sf | SUPERFAMILY | Methylated DNA-protein cysteine methyltransferase domain superfamily |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
28 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| DNA binding | Hs | molecular function |
| catalytic activity | Hs | molecular function |
| methylated-DNA-[protein]-cysteine S-methyltransferase activity | Hs | molecular function |
| calcium ion binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| nucleoplasm | Hs | cellular component |
| DNA ligation | Hs | biological process |
| DNA repair | Hs | biological process |
| DNA methylation | Hs | biological process |
| DNA dealkylation involved in DNA repair | Hs | biological process |
| cellular response to DNA damage stimulus | Hs | biological process |
| methyltransferase activity | Hs | molecular function |
| DNA-methyltransferase activity | Hs | molecular function |
| response to toxic substance | Hs | biological process |
| response to organic cyclic compound | Hs | biological process |
| membrane | Hs | cellular component |
| transferase activity | Hs | molecular function |
| methylation | Hs | biological process |
| cellular response to oxidative stress | Hs | biological process |
| response to drug | Hs | biological process |
| negative regulation of apoptotic process | Hs | biological process |
| regulation of cysteine-type endopeptidase activity involved in apoptotic process | Hs | biological process |
| response to ethanol | Hs | biological process |
| positive regulation of DNA repair | Hs | biological process |
| metal ion binding | Hs | molecular function |
| negative regulation of cell death | Hs | biological process |
| cellular response to organic cyclic compound | Hs | biological process |
| cellular response to ionizing radiation | Hs | biological process |
GO (Blast)
11 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| DNA binding | Hs | molecular function | 79.3 | 2.13e-18 |
| catalytic activity | Hs | molecular function | 79.3 | 2.13e-18 |
| methylated-DNA-[protein]-cysteine S-methyltransferase activity | Hs | molecular function | 79.3 | 2.13e-18 |
| calcium ion binding | Hs | molecular function | 79.3 | 2.13e-18 |
| nucleus | Hs | cellular component | 79.3 | 2.13e-18 |
| nucleoplasm | Hs | cellular component | 79.3 | 2.13e-18 |
| methyltransferase activity | Hs | molecular function | 79.3 | 2.13e-18 |
| DNA-methyltransferase activity | Hs | molecular function | 79.3 | 2.13e-18 |
| membrane | Hs | cellular component | 79.3 | 2.13e-18 |
| transferase activity | Hs | molecular function | 79.3 | 2.13e-18 |
| metal ion binding | Hs | molecular function | 79.3 | 2.13e-18 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| catalytic activity | CDD | molecular function | 2.97014E-16 |
| methylated-DNA-[protein]-cysteine S-methyltransferase activity | SUPERFAMILY | molecular function | 5.1E-5 |
| DNA repair | CDD | biological process | 2.97014E-16 |
