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GENE CARD

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Gene Card

Best human hits

ACTN1; ACTN2; ACTN4

Species

M.occidentalis

Unique Gene ID

Moocci.g00030764

Gene Model ID

Moocci.CG.ELv1_2.S653808.g30764

Location

S653808:26466..35357

Transcript Models and Sequences

  Moocci.CG.ELv1_2.S653808.g30764.01.t
Moocci.CG.ELv1_2.S653808.g30764.02.t
Moocci.CG.ELv1_2.S653808.g30764.03.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

17 results

IPR Term Analysis Definition
EF_hand_dom Pfam EF-hand domain
Spectrin/alpha-actinin SMART Spectrin/alpha-actinin
CH-domain CDD Calponin homology domain
EF_hand_dom ProSiteProfiles EF-hand domain
CH-domain ProSiteProfiles Calponin homology domain
CH-domain Pfam Calponin homology domain
EF_hand_dom SMART EF-hand domain
EF-hand_Ca_insen Pfam EF-hand, Ca insensitive
CH_dom_sf Gene3D CH domain superfamily
CH_dom_sf SUPERFAMILY CH domain superfamily
CH-domain SMART Calponin homology domain
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair
Spectrin_repeat Pfam Spectrin repeat
Actinin_actin-bd_CS ProSitePatterns Actinin-type actin-binding domain, conserved site
EF_Hand_1_Ca_BS ProSitePatterns EF-Hand 1, calcium-binding site
EF_hand_dom CDD EF-hand domain
ACTN4 PANTHER Alpha-actinin-4

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

94 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
MAPK cascade Hs biological process
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
stress fiber Hs cellular component
ruffle Hs cellular component
nucleoside binding Hs molecular function
platelet degranulation Hs biological process
RNA binding Hs molecular function
double-stranded RNA binding Hs molecular function
actin binding Hs molecular function
Ras guanyl-nucleotide exchange factor activity Hs molecular function
integrin binding Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
actin filament Hs cellular component
plasma membrane Hs cellular component
brush border Hs cellular component
cell-cell junction Hs cellular component
fascia adherens Hs cellular component
focal adhesion Hs cellular component
muscle contraction Hs biological process
actin filament organization Hs biological process
cell adhesion Hs biological process
cytoskeletal protein binding Hs molecular function
structural constituent of muscle Hs molecular function
protein transport Hs biological process
actin cytoskeleton Hs cellular component
membrane Hs cellular component
nuclear body Hs cellular component
vinculin binding Hs molecular function
protein domain specific binding Hs molecular function
sarcomere Hs cellular component
Z disc Hs cellular component
vesicle transport along actin filament Hs biological process
cell junction Hs cellular component
filopodium Hs cellular component
platelet formation Hs biological process
LIM domain binding Hs molecular function
positive regulation of cell migration Hs biological process
ligand-dependent nuclear receptor transcription coactivator activity Hs molecular function
thyroid hormone receptor coactivator activity Hs molecular function
intracellular ribonucleoprotein complex Hs cellular component
cortical actin cytoskeleton Hs cellular component
platelet alpha granule lumen Hs cellular component
pseudopodium Hs cellular component
titin binding Hs molecular function
chromatin DNA binding Hs molecular function
macromolecular complex Hs cellular component
nuclear hormone receptor binding Hs molecular function
peroxisome proliferator activated receptor signaling pathway Hs biological process
regulation of membrane potential Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
retinoic acid receptor binding Hs molecular function
regulation of apoptotic process Hs biological process
cell projection Hs cellular component
dendritic spine Hs cellular component
negative regulation of potassium ion transport Hs biological process
ion channel binding Hs molecular function
sarcomere organization Hs biological process
metal ion binding Hs molecular function
protein dimerization activity Hs molecular function
focal adhesion assembly Hs biological process
retinoic acid receptor signaling pathway Hs biological process
perinuclear region of cytoplasm Hs cellular component
actin filament binding Hs molecular function
actin filament bundle assembly Hs biological process
protein homotetramerization Hs biological process
FATZ binding Hs molecular function
actin filament network formation Hs biological process
actin crosslink formation Hs biological process
cardiac muscle cell development Hs biological process
extracellular exosome Hs cellular component
titin Z domain binding Hs molecular function
protein localization to plasma membrane Hs biological process
negative regulation of substrate adhesion-dependent cell spreading Hs biological process
regulation of nucleic acid-templated transcription Hs biological process
negative regulation of protein localization to cell surface Hs biological process
positive regulation of cation channel activity Hs biological process
response to hypoxia Hs biological process
skeletal muscle atrophy Hs biological process
cortical cytoskeleton Hs cellular component
neuron projection Hs cellular component
protein N-terminus binding Hs molecular function
positive regulation of skeletal muscle fiber development Hs biological process
bone morphogenesis Hs biological process
bicellular tight junction assembly Hs biological process

GO (Blast)

60 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 1264 0.0
stress fiber Hs cellular component 1275 0.0
ruffle Hs cellular component 1275 0.0
nucleoside binding Hs molecular function 1264 0.0
RNA binding Hs molecular function 1264 0.0
double-stranded RNA binding Hs molecular function 1275 0.0
actin binding Hs molecular function 1281 0.0
Ras guanyl-nucleotide exchange factor activity Hs molecular function 1281 0.0
integrin binding Hs molecular function 1281 0.0
calcium ion binding Hs molecular function 1281 0.0
protein binding Hs molecular function 1281 0.0
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function 1281 0.0
extracellular region Hs cellular component 1281 0.0
extracellular space Hs cellular component 1275 0.0
intracellular Hs cellular component 1275 0.0
nucleus Hs cellular component 1264 0.0
cytoplasm Hs cellular component 1281 0.0
cytosol Hs cellular component 1281 0.0
cytoskeleton Hs cellular component 1281 0.0
actin filament Hs cellular component 1281 0.0
plasma membrane Hs cellular component 1281 0.0
brush border Hs cellular component 1275 0.0
cell-cell junction Hs cellular component 1275 0.0
fascia adherens Hs cellular component 1275 0.0
focal adhesion Hs cellular component 1281 0.0
cytoskeletal protein binding Hs molecular function 1281 0.0
structural constituent of muscle Hs molecular function 1281 0.0
actin cytoskeleton Hs cellular component 1264 0.0
membrane Hs cellular component 1275 0.0
nuclear body Hs cellular component 1264 0.0
vinculin binding Hs molecular function 1275 0.0
protein domain specific binding Hs molecular function 1281 0.0
sarcomere Hs cellular component 1281 0.0
Z disc Hs cellular component 1281 0.0
cell junction Hs cellular component 1275 0.0
filopodium Hs cellular component 1281 0.0
LIM domain binding Hs molecular function 1281 0.0
ligand-dependent nuclear receptor transcription coactivator activity Hs molecular function 1281 0.0
thyroid hormone receptor coactivator activity Hs molecular function 1281 0.0
intracellular ribonucleoprotein complex Hs cellular component 1264 0.0
cortical actin cytoskeleton Hs cellular component 1281 0.0
platelet alpha granule lumen Hs cellular component 1281 0.0
pseudopodium Hs cellular component 1281 0.0
titin binding Hs molecular function 1281 0.0
chromatin DNA binding Hs molecular function 1264 0.0
macromolecular complex Hs cellular component 1264 0.0
nuclear hormone receptor binding Hs molecular function 1264 0.0
identical protein binding Hs molecular function 1281 0.0
protein homodimerization activity Hs molecular function 1281 0.0
retinoic acid receptor binding Hs molecular function 1264 0.0
cell projection Hs cellular component 1275 0.0
dendritic spine Hs cellular component 1281 0.0
ion channel binding Hs molecular function 1281 0.0
metal ion binding Hs molecular function 1281 0.0
protein dimerization activity Hs molecular function 1281 0.0
perinuclear region of cytoplasm Hs cellular component 1264 0.0
actin filament binding Hs molecular function 1281 0.0
FATZ binding Hs molecular function 1281 0.0
extracellular exosome Hs cellular component 1281 0.0
titin Z domain binding Hs molecular function 1281 0.0

GO (InterProScan)

2 results

GO Term Analysis Type e-value
calcium ion binding CDD molecular function 4.6806E-12
protein binding Pfam molecular function 4.2E-28

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