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GENE CARD

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Gene Card

Best human hits

ARAF; BRAF; RAF1

Species

M.oculata

Unique Gene ID

Moocul.g00009034

Gene Model ID

Moocul.CG.ELv1_2.S101026.g09034

Location

S101026:1102..16146

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Prot_kinase_dom SMART Protein kinase domain
PE/DAG-bd Pfam Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
PE/DAG-bd SMART Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Prot_kinase_dom ProSiteProfiles Protein kinase domain
PE/DAG-bd ProSitePatterns Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
PE/DAG-bd CDD Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
PE/DAG-bd ProSiteProfiles Protein kinase C-like, phorbol ester/diacylglycerol-binding domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

95 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
MAPK cascade Hs biological process
nucleotide binding Hs molecular function
activation of MAPKK activity Hs biological process
response to hypoxia Hs biological process
cellular glucose homeostasis Hs biological process
positive regulation of protein phosphorylation Hs biological process
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
MAP kinase kinase kinase activity Hs molecular function
signal transducer activity, downstream of receptor Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
mitochondrial outer membrane Hs cellular component
Golgi apparatus Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
cellular protein modification process Hs biological process
protein phosphorylation Hs biological process
apoptotic process Hs biological process
signal transduction Hs biological process
activation of adenylate cyclase activity Hs biological process
multicellular organism development Hs biological process
heart development Hs biological process
adenylate cyclase binding Hs molecular function
cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
visual learning Hs biological process
animal organ morphogenesis Hs biological process
negative regulation of signal transduction Hs biological process
positive regulation of gene expression Hs biological process
adenylate cyclase activator activity Hs molecular function
membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
nuclear speck Hs cellular component
transferase activity Hs molecular function
Ras GTPase binding Hs molecular function
enzyme binding Hs molecular function
cell differentiation Hs biological process
platelet activation Hs biological process
thyroid gland development Hs biological process
pseudopodium Hs cellular component
negative regulation of protein complex assembly Hs biological process
mitogen-activated protein kinase kinase binding Hs molecular function
regulation of TOR signaling Hs biological process
regulation of proteasomal ubiquitin-dependent protein catabolic process Hs biological process
positive regulation of peptidyl-serine phosphorylation Hs biological process
ion transmembrane transport Hs biological process
somatic stem cell population maintenance Hs biological process
regulation of Rho protein signal transduction Hs biological process
intracellular signal transduction Hs biological process
wound healing Hs biological process
regulation of cell proliferation Hs biological process
identical protein binding Hs molecular function
regulation of apoptotic process Hs biological process
neuron projection Hs cellular component
negative regulation of apoptotic process Hs biological process
positive regulation of catalytic activity Hs biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
intracellular membrane-bounded organelle Hs cellular component
positive T cell selection Hs biological process
response to peptide hormone Hs biological process
negative regulation of neuron apoptotic process Hs biological process
cell body Hs cellular component
intermediate filament cytoskeleton organization Hs biological process
regulation of T cell differentiation Hs biological process
regulation of cell differentiation Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
alpha-beta T cell differentiation Hs biological process
metal ion binding Hs molecular function
protein heterodimerization activity Hs molecular function
neurotrophin TRK receptor signaling pathway Hs biological process
thymus development Hs biological process
regulation of axon regeneration Hs biological process
positive regulation of axon regeneration Hs biological process
positive regulation of axonogenesis Hs biological process
T cell receptor signaling pathway Hs biological process
protein heterooligomerization Hs biological process
positive regulation of stress fiber assembly Hs biological process
response to cAMP Hs biological process
long-term synaptic potentiation Hs biological process
head morphogenesis Hs biological process
face development Hs biological process
positive regulation of ERK1 and ERK2 cascade Hs biological process
cellular response to calcium ion Hs biological process
establishment of protein localization to membrane Hs biological process
positive regulation of substrate adhesion-dependent cell spreading Hs biological process
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors Hs biological process
regulation of cell motility Hs biological process
negative regulation of synaptic vesicle exocytosis Hs biological process

GO (Blast)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 533 0.0
protein kinase activity Hs molecular function 533 0.0
protein serine/threonine kinase activity Hs molecular function 533 0.0
MAP kinase kinase kinase activity Hs molecular function 533 0.0
signal transducer activity, downstream of receptor Hs molecular function 533 0.0
calcium ion binding Hs molecular function 533 0.0
protein binding Hs molecular function 533 0.0
ATP binding Hs molecular function 533 0.0
intracellular Hs cellular component 533 0.0
nucleus Hs cellular component 533 0.0
cytoplasm Hs cellular component 533 0.0
mitochondrion Hs cellular component 533 0.0
mitochondrial outer membrane Hs cellular component 427 4.47e-142
Golgi apparatus Hs cellular component 427 4.47e-142
cytosol Hs cellular component 533 0.0
plasma membrane Hs cellular component 533 0.0
adenylate cyclase binding Hs molecular function 427 4.47e-142
adenylate cyclase activator activity Hs molecular function 427 4.47e-142
membrane Hs cellular component 533 0.0
kinase activity Hs molecular function 533 0.0
nuclear speck Hs cellular component 427 4.47e-142
transferase activity Hs molecular function 533 0.0
Ras GTPase binding Hs molecular function 533 0.0
enzyme binding Hs molecular function 427 4.47e-142
pseudopodium Hs cellular component 427 4.47e-142
mitogen-activated protein kinase kinase binding Hs molecular function 533 0.0
identical protein binding Hs molecular function 533 0.0
neuron projection Hs cellular component 533 0.0
intracellular membrane-bounded organelle Hs cellular component 533 0.0
cell body Hs cellular component 533 0.0
metal ion binding Hs molecular function 533 0.0
protein heterodimerization activity Hs molecular function 533 0.0

GO (InterProScan)

4 results

GO Term Analysis Type e-value
protein kinase activity SMART molecular function 6.7E-58
ATP binding SMART molecular function 6.7E-58
protein phosphorylation SMART biological process 6.7E-58
intracellular signal transduction CDD biological process 7.69935E-10