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Gene Card

Best human hits

CASP2; CASP3; CASP9

Species

M.oculata

Unique Gene ID

Moocul.g00009526

Gene Model ID

Moocul.CG.ELv1_2.S103067.g09526

Location

S103067:44113..51379

Transcript Models and Sequences

  Moocul.CG.ELv1_2.S103067.g09526.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
Caspase_2 PANTHER Caspase-2
CARD ProSiteProfiles CARD domain
Pept_C14_p10 ProSiteProfiles Peptidase C14, caspase non-catalytic subunit p10
Pept_C14A CDD Peptidase C14A, caspase catalytic domain
Pept_C14_p20 ProSiteProfiles Peptidase C14, p20 domain
CARD SMART CARD domain
Caspase_his_AS ProSitePatterns Peptidase family C14A, His active site
Pept_C14A SMART Peptidase C14A, caspase catalytic domain
Caspase_cys_AS ProSitePatterns Peptidase family C14A, cysteine active site
DEATH-like_dom_sf SUPERFAMILY Death-like domain superfamily
Caspase-like_dom_sf SUPERFAMILY Caspase-like domain superfamily
CARD Pfam CARD domain
Pept_C14A PRINTS Peptidase C14A, caspase catalytic domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
neural retina development Hs biological process
cysteine-type endopeptidase activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
cytosol Hs cellular component
proteolysis Hs biological process
apoptotic process Hs biological process
activation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
brain development Hs biological process
aging Hs biological process
peptidase activity Hs molecular function
cysteine-type peptidase activity Hs molecular function
intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
membrane Hs cellular component
protein processing Hs biological process
hydrolase activity Hs molecular function
enzyme binding Hs molecular function
protein domain specific binding Hs molecular function
ectopic germ cell programmed cell death Hs biological process
identical protein binding Hs molecular function
regulation of apoptotic process Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
positive regulation of neuron apoptotic process Hs biological process
cellular response to mechanical stimulus Hs biological process
cysteine-type endopeptidase activity involved in apoptotic process Hs molecular function
apoptotic signaling pathway Hs biological process
extrinsic apoptotic signaling pathway in absence of ligand Hs biological process
execution phase of apoptosis Hs biological process
cysteine-type endopeptidase activity involved in execution phase of apoptosis Hs molecular function
positive regulation of apoptotic signaling pathway Hs biological process

GO (Blast)

30 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
protease binding Hs molecular function 143 2.27e-39
aspartic-type endopeptidase activity Hs molecular function 143 2.27e-39
cysteine-type endopeptidase activity Hs molecular function 243 3.59e-75
cyclin-dependent protein serine/threonine kinase inhibitor activity Hs molecular function 143 2.27e-39
death receptor binding Hs molecular function 143 2.27e-39
protein binding Hs molecular function 243 3.59e-75
nucleus Hs cellular component 243 3.59e-75
nucleoplasm Hs cellular component 143 2.27e-39
cytoplasm Hs cellular component 243 3.59e-75
mitochondrion Hs cellular component 243 3.59e-75
cytosol Hs cellular component 243 3.59e-75
plasma membrane Hs cellular component 143 2.27e-39
enzyme activator activity Hs molecular function 134 1.16e-34
peptidase activity Hs molecular function 243 3.59e-75
cysteine-type peptidase activity Hs molecular function 243 3.59e-75
cysteine-type endopeptidase activator activity involved in apoptotic process Hs molecular function 143 2.27e-39
phospholipase A2 activator activity Hs molecular function 143 2.27e-39
membrane Hs cellular component 243 3.59e-75
hydrolase activity Hs molecular function 243 3.59e-75
SH3 domain binding Hs molecular function 134 1.16e-34
enzyme binding Hs molecular function 243 3.59e-75
protein kinase binding Hs molecular function 134 1.16e-34
protein domain specific binding Hs molecular function 243 3.59e-75
death-inducing signaling complex Hs cellular component 143 2.27e-39
macromolecular complex Hs cellular component 134 1.16e-34
identical protein binding Hs molecular function 243 3.59e-75
apoptosome Hs cellular component 134 1.16e-34
membrane raft Hs cellular component 143 2.27e-39
cysteine-type endopeptidase activity involved in apoptotic process Hs molecular function 243 3.59e-75
cysteine-type endopeptidase activity involved in execution phase of apoptosis Hs molecular function 243 3.59e-75

GO (InterProScan)

5 results

GO Term Analysis Type e-value
cysteine-type endopeptidase activity ProSiteProfiles molecular function 33.878
proteolysis ProSiteProfiles biological process 33.878
cysteine-type peptidase activity SMART molecular function 9.8E-81
regulation of apoptotic process SMART biological process 1.0E-13
cysteine-type endopeptidase activity involved in execution phase of apoptosis PANTHER molecular function 4.1E-99

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