Gene Card
Best human hits
LDLR; LRP1; SORL1
Species
Unique Gene ID
Moocul.g00009624
Gene Model ID
Moocul.CG.ELv1_2.S103417.g09624
Location
S103417:35119..45370
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
LDL_receptor-like_sf | SUPERFAMILY | LDL receptor-like superfamily |
LDrepeatLR_classA_rpt | ProSiteProfiles | Low-density lipoprotein (LDL) receptor class A repeat |
LDrepeatLR_classA_rpt | PRINTS | Low-density lipoprotein (LDL) receptor class A repeat |
LDLR_class-A_CS | ProSitePatterns | Low-density lipoprotein (LDL) receptor class A, conserved site |
MFS_trans_sf | SUPERFAMILY | MFS transporter superfamily |
LDrepeatLR_classA_rpt | SMART | Low-density lipoprotein (LDL) receptor class A repeat |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
Golgi membrane | Hs | cellular component | 60.5 | 3.17e-09 |
amyloid-beta binding | Hs | molecular function | 67.0 | 2.46e-11 |
virus receptor activity | Hs | molecular function | 67.0 | 2.46e-11 |
protease binding | Hs | molecular function | 67.0 | 2.46e-11 |
RNA binding | Hs | molecular function | 52.4 | 9.52e-07 |
receptor activity | Hs | molecular function | 52.4 | 9.52e-07 |
transmembrane signaling receptor activity | Hs | molecular function | 60.5 | 3.17e-09 |
low-density lipoprotein receptor activity | Hs | molecular function | 67.0 | 2.46e-11 |
scavenger receptor activity | Hs | molecular function | 52.4 | 9.52e-07 |
calcium ion binding | Hs | molecular function | 67.0 | 2.46e-11 |
protein binding | Hs | molecular function | 67.0 | 2.46e-11 |
extracellular region | Hs | cellular component | 60.5 | 3.17e-09 |
extracellular space | Hs | cellular component | 67.0 | 2.46e-11 |
intracellular | Hs | cellular component | 67.0 | 2.46e-11 |
nucleus | Hs | cellular component | 52.4 | 9.52e-07 |
nuclear envelope lumen | Hs | cellular component | 60.5 | 3.17e-09 |
cytoplasm | Hs | cellular component | 52.4 | 9.52e-07 |
lysosome | Hs | cellular component | 67.0 | 2.46e-11 |
lysosomal membrane | Hs | cellular component | 52.4 | 9.52e-07 |
endosome | Hs | cellular component | 67.0 | 2.46e-11 |
early endosome | Hs | cellular component | 67.0 | 2.46e-11 |
late endosome | Hs | cellular component | 67.0 | 2.46e-11 |
endoplasmic reticulum | Hs | cellular component | 60.5 | 3.17e-09 |
Golgi apparatus | Hs | cellular component | 67.0 | 2.46e-11 |
trans-Golgi network | Hs | cellular component | 60.5 | 3.17e-09 |
plasma membrane | Hs | cellular component | 67.0 | 2.46e-11 |
integral component of plasma membrane | Hs | cellular component | 67.0 | 2.46e-11 |
clathrin-coated pit | Hs | cellular component | 67.0 | 2.46e-11 |
focal adhesion | Hs | cellular component | 52.4 | 9.52e-07 |
external side of plasma membrane | Hs | cellular component | 67.0 | 2.46e-11 |
cell surface | Hs | cellular component | 67.0 | 2.46e-11 |
endosome membrane | Hs | cellular component | 67.0 | 2.46e-11 |
membrane | Hs | cellular component | 67.0 | 2.46e-11 |
integral component of membrane | Hs | cellular component | 67.0 | 2.46e-11 |
basolateral plasma membrane | Hs | cellular component | 67.0 | 2.46e-11 |
alpha-2 macroglobulin receptor activity | Hs | molecular function | 52.4 | 9.52e-07 |
clathrin-coated vesicle | Hs | cellular component | 52.4 | 9.52e-07 |
low-density lipoprotein particle binding | Hs | molecular function | 67.0 | 2.46e-11 |
apolipoprotein receptor activity | Hs | molecular function | 52.4 | 9.52e-07 |
very-low-density lipoprotein particle receptor activity | Hs | molecular function | 67.0 | 2.46e-11 |
ADP-ribosylation factor binding | Hs | molecular function | 60.5 | 3.17e-09 |
dendrite | Hs | cellular component | 52.4 | 9.52e-07 |
endocytic vesicle membrane | Hs | cellular component | 52.4 | 9.52e-07 |
clathrin-coated endocytic vesicle membrane | Hs | cellular component | 67.0 | 2.46e-11 |
Golgi cisterna | Hs | cellular component | 60.5 | 3.17e-09 |
clathrin heavy chain binding | Hs | molecular function | 67.0 | 2.46e-11 |
apolipoprotein binding | Hs | molecular function | 52.4 | 9.52e-07 |
low-density lipoprotein particle | Hs | cellular component | 67.0 | 2.46e-11 |
endolysosome membrane | Hs | cellular component | 67.0 | 2.46e-11 |
somatodendritic compartment | Hs | cellular component | 67.0 | 2.46e-11 |
identical protein binding | Hs | molecular function | 67.0 | 2.46e-11 |
lipoprotein transporter activity | Hs | molecular function | 52.4 | 9.52e-07 |
neuronal cell body | Hs | cellular component | 52.4 | 9.52e-07 |
receptor complex | Hs | cellular component | 67.0 | 2.46e-11 |
heparan sulfate proteoglycan binding | Hs | molecular function | 52.4 | 9.52e-07 |
macromolecular complex binding | Hs | molecular function | 52.4 | 9.52e-07 |
apical part of cell | Hs | cellular component | 67.0 | 2.46e-11 |
metal ion binding | Hs | molecular function | 52.4 | 9.52e-07 |
recycling endosome | Hs | cellular component | 60.5 | 3.17e-09 |
extracellular exosome | Hs | cellular component | 60.5 | 3.17e-09 |
lipoprotein particle receptor binding | Hs | molecular function | 52.4 | 9.52e-07 |
sorting endosome | Hs | cellular component | 67.0 | 2.46e-11 |
plasma membrane protein complex | Hs | cellular component | 52.4 | 9.52e-07 |
PCSK9-LDLR complex | Hs | cellular component | 67.0 | 2.46e-11 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | PRINTS | molecular function | 2.5E-12 |