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GENE CARD

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Gene Card

Best human hits

LRP4; LRP6

Species

M.oculata

Unique Gene ID

Moocul.g00013274

Gene Model ID

Moocul.CG.ELv1_2.S113966.g13274

Location

S113966:7213..24060

Transcript Models and Sequences

  Moocul.CG.ELv1_2.S113966.g13274.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

20 results

IPR Term Analysis Definition
LRP4 PANTHER Low-density lipoprotein receptor-related protein 4
LDL_receptor-like_sf SUPERFAMILY LDL receptor-like superfamily
LDLR_classB_rpt ProSiteProfiles LDLR class B repeat
LDrepeatLR_classA_rpt CDD Low-density lipoprotein (LDL) receptor class A repeat
EGF-like_dom SMART EGF-like domain
LDLR_classB_rpt Pfam LDLR class B repeat
EGF-like_CS ProSitePatterns EGF-like, conserved site
LDrepeatLR_classA_rpt ProSiteProfiles Low-density lipoprotein (LDL) receptor class A repeat
LDLR_class-A_CS ProSitePatterns Low-density lipoprotein (LDL) receptor class A, conserved site
EGF-type_Asp/Asn_hydroxyl_site ProSitePatterns EGF-type aspartate/asparagine hydroxylation site
LDrepeatLR_classA_rpt SMART Low-density lipoprotein (LDL) receptor class A repeat
LDrepeatLR_classA_rpt Pfam Low-density lipoprotein (LDL) receptor class A repeat
6-blade_b-propeller_TolB-like Gene3D Six-bladed beta-propeller, TolB-like
EGF-like_Ca-bd_dom Pfam EGF-like calcium-binding domain
LDrepeatLR_classA_rpt PRINTS Low-density lipoprotein (LDL) receptor class A repeat
LDLR_classB_rpt SMART LDLR class B repeat
EGF-like_dom ProSiteProfiles EGF-like domain
EGF_Ca-bd_CS ProSitePatterns EGF-like calcium-binding, conserved site
Growth_fac_rcpt_cys_sf SUPERFAMILY Growth factor receptor cysteine-rich domain superfamily
EGF-like_Ca-bd_dom SMART EGF-like calcium-binding domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

49 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
kidney development Hs biological process
regulation of protein phosphorylation Hs biological process
calcium ion binding Hs molecular function
protein binding Hs molecular function
plasma membrane Hs cellular component
endocytosis Hs biological process
multicellular organism development Hs biological process
protein localization Hs biological process
dorsal/ventral pattern formation Hs biological process
proximal/distal pattern formation Hs biological process
cell surface Hs cellular component
postsynaptic density Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
Wnt signaling pathway Hs biological process
flotillin complex Hs cellular component
Wnt-protein binding Hs molecular function
cell differentiation Hs biological process
negative regulation of Wnt signaling pathway Hs biological process
negative regulation of ossification Hs biological process
embryonic limb morphogenesis Hs biological process
dendrite Hs cellular component
BMP signaling pathway Hs biological process
receptor tyrosine kinase binding Hs molecular function
neuromuscular junction Hs cellular component
apolipoprotein binding Hs molecular function
protein homodimerization activity Hs molecular function
Wnt-activated receptor activity Hs molecular function
neuronal cell body Hs cellular component
receptor clustering Hs biological process
receptor complex Hs cellular component
Wnt signaling pathway involved in dorsal/ventral axis specification Hs biological process
animal organ development Hs biological process
dendrite morphogenesis Hs biological process
anatomical structure development Hs biological process
positive regulation of peptidyl-tyrosine phosphorylation Hs biological process
negative regulation of axonogenesis Hs biological process
synapse organization Hs biological process
synaptic growth at neuromuscular junction Hs biological process
protein heterotetramerization Hs biological process
limb development Hs biological process
regulation of canonical Wnt signaling pathway Hs biological process
skeletal muscle acetylcholine-gated channel clustering Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
synaptic membrane Hs cellular component
postsynaptic membrane assembly Hs biological process
presynaptic membrane assembly Hs biological process
scaffold protein binding Hs molecular function
positive regulation of skeletal muscle acetylcholine-gated channel clustering Hs biological process

GO (Blast)

38 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
low-density lipoprotein receptor activity Hs molecular function 857 0.0
receptor binding Hs molecular function 857 0.0
frizzled binding Hs molecular function 857 0.0
calcium ion binding Hs molecular function 1613 0.0
protein binding Hs molecular function 1613 0.0
extracellular region Hs cellular component 857 0.0
early endosome Hs cellular component 857 0.0
endoplasmic reticulum Hs cellular component 857 0.0
Golgi apparatus Hs cellular component 857 0.0
plasma membrane Hs cellular component 1613 0.0
caveola Hs cellular component 857 0.0
cell surface Hs cellular component 1613 0.0
postsynaptic density Hs cellular component 1613 0.0
membrane Hs cellular component 1613 0.0
integral component of membrane Hs cellular component 1613 0.0
flotillin complex Hs cellular component 1613 0.0
Wnt-protein binding Hs molecular function 1613 0.0
kinase inhibitor activity Hs molecular function 857 0.0
toxin transporter activity Hs molecular function 857 0.0
dendrite Hs cellular component 1613 0.0
receptor tyrosine kinase binding Hs molecular function 1613 0.0
cytoplasmic vesicle Hs cellular component 857 0.0
neuromuscular junction Hs cellular component 1613 0.0
early endosome membrane Hs cellular component 857 0.0
apolipoprotein binding Hs molecular function 1613 0.0
identical protein binding Hs molecular function 857 0.0
protein homodimerization activity Hs molecular function 1613 0.0
Wnt-activated receptor activity Hs molecular function 1613 0.0
neuronal cell body Hs cellular component 1613 0.0
receptor complex Hs cellular component 1613 0.0
membrane raft Hs cellular component 857 0.0
synapse Hs cellular component 857 0.0
coreceptor activity involved in Wnt signaling pathway Hs molecular function 857 0.0
synaptic membrane Hs cellular component 1613 0.0
scaffold protein binding Hs molecular function 1613 0.0
coreceptor activity involved in canonical Wnt signaling pathway Hs molecular function 857 0.0
Wnt-Frizzled-LRP5/6 complex Hs cellular component 857 0.0
Wnt signalosome Hs cellular component 857 0.0

GO (InterProScan)

5 results

GO Term Analysis Type e-value
calcium ion binding SMART molecular function 9.0E-9
protein binding PRINTS molecular function 1.4E-32
BMP signaling pathway PANTHER biological process 0.0
animal organ development PANTHER biological process 0.0
regulation of canonical Wnt signaling pathway PANTHER biological process 0.0

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