Gene Card
Best human hits
LNX2; RNF146; RNF168
Species
Unique Gene ID
Moocul.g00015112
Gene Model ID
Moocul.CG.ELv1_2.S128768.g15112
Location
S128768:10102..12791
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Znf_RING | ProSiteProfiles | Zinc finger, RING-type |
WWE_dom_sf | Gene3D | WWE domain superfamily |
Znf_RING_CS | ProSitePatterns | Zinc finger, RING-type, conserved site |
WWE-dom_subgr | SMART | WWE domain, subgroup |
WWE-dom | Pfam | WWE domain |
WWE-dom | ProSiteProfiles | WWE domain |
WWE_dom_sf | SUPERFAMILY | WWE domain superfamily |
Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
RNF146 | PANTHER | E3 ubiquitin-protein ligase RNF146 |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
ubiquitin-protein transferase activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
ubiquitin-dependent protein catabolic process | Hs | biological process |
zinc ion binding | Hs | molecular function |
Wnt signaling pathway | Hs | biological process |
protein ubiquitination | Hs | biological process |
protein deubiquitination | Hs | biological process |
transferase activity | Hs | molecular function |
metal ion binding | Hs | molecular function |
protein autoubiquitination | Hs | biological process |
ubiquitin protein ligase activity | Hs | molecular function |
protein K48-linked ubiquitination | Hs | biological process |
poly-ADP-D-ribose binding | Hs | molecular function |
positive regulation of canonical Wnt signaling pathway | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ubiquitin ligase complex | Hs | cellular component | 43.9 | 1.08e-04 |
chromatin binding | Hs | molecular function | 43.9 | 1.08e-04 |
ubiquitin-protein transferase activity | Hs | molecular function | 172 | 6.28e-51 |
protein binding | Hs | molecular function | 172 | 6.28e-51 |
nucleus | Hs | cellular component | 172 | 6.28e-51 |
nucleoplasm | Hs | cellular component | 172 | 6.28e-51 |
cytoplasm | Hs | cellular component | 172 | 6.28e-51 |
cytosol | Hs | cellular component | 172 | 6.28e-51 |
plasma membrane | Hs | cellular component | 172 | 6.28e-51 |
zinc ion binding | Hs | molecular function | 172 | 6.28e-51 |
transferase activity | Hs | molecular function | 172 | 6.28e-51 |
PDZ domain binding | Hs | molecular function | 45.8 | 2.68e-05 |
nucleosome binding | Hs | molecular function | 43.9 | 1.08e-04 |
macromolecular complex | Hs | cellular component | 43.9 | 1.08e-04 |
site of double-strand break | Hs | cellular component | 43.9 | 1.08e-04 |
histone binding | Hs | molecular function | 43.9 | 1.08e-04 |
ubiquitin binding | Hs | molecular function | 43.9 | 1.08e-04 |
metal ion binding | Hs | molecular function | 172 | 6.28e-51 |
ubiquitin protein ligase activity | Hs | molecular function | 172 | 6.28e-51 |
K63-linked polyubiquitin modification-dependent protein binding | Hs | molecular function | 43.9 | 1.08e-04 |
poly-ADP-D-ribose binding | Hs | molecular function | 172 | 6.28e-51 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
zinc ion binding | SMART | molecular function | 1.8E-18 |
Wnt signaling pathway | PANTHER | biological process | 1.1E-59 |
ubiquitin protein ligase activity | PANTHER | molecular function | 1.1E-59 |
poly-ADP-D-ribose binding | PANTHER | molecular function | 1.1E-59 |