Gene Card
Best human hits
USP2; USP4; USP8
Species
Unique Gene ID
Moocul.g00000159
Gene Model ID
Moocul.CG.ELv1_2.S6154.g00159
Location
S6154:4165..16982
Transcript Models and Sequences
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Peptidase_C19_UCH | Pfam | Peptidase C19, ubiquitin carboxyl-terminal hydrolase |
WW_dom | SMART | WW domain |
Rhodanese-like_dom_sf | Gene3D | Rhodanese-like domain superfamily |
WW_dom | ProSiteProfiles | WW domain |
USP_CS | ProSitePatterns | Ubiquitin specific protease, conserved site |
USP_dom | ProSiteProfiles | Ubiquitin specific protease domain |
Rhodanese-like_dom | ProSiteProfiles | Rhodanese-like domain |
WW_dom | Pfam | WW domain |
USP8_dimer | Pfam | USP8 dimerisation domain |
Rhodanese-like_dom_sf | SUPERFAMILY | Rhodanese-like domain superfamily |
WW_dom | CDD | WW domain |
WW_dom_sf | SUPERFAMILY | WW domain superfamily |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
mitotic cytokinesis | Hs | biological process |
cysteine-type endopeptidase activity | Hs | molecular function |
thiol-dependent ubiquitin-specific protease activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
endosome | Hs | cellular component |
early endosome | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
proteolysis | Hs | biological process |
ubiquitin-dependent protein catabolic process | Hs | biological process |
endosome organization | Hs | biological process |
cell cycle | Hs | biological process |
peptidase activity | Hs | molecular function |
cysteine-type peptidase activity | Hs | molecular function |
cell proliferation | Hs | biological process |
endosome membrane | Hs | cellular component |
postsynaptic density | Hs | cellular component |
membrane | Hs | cellular component |
protein deubiquitination | Hs | biological process |
hydrolase activity | Hs | molecular function |
SH3 domain binding | Hs | molecular function |
extrinsic component of plasma membrane | Hs | cellular component |
midbody | Hs | cellular component |
extrinsic component of endosome membrane | Hs | cellular component |
thiol-dependent ubiquitinyl hydrolase activity | Hs | molecular function |
dendritic spine | Hs | cellular component |
cadherin binding | Hs | molecular function |
protein K63-linked deubiquitination | Hs | biological process |
protein K48-linked deubiquitination | Hs | biological process |
positive regulation of canonical Wnt signaling pathway | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
cysteine-type endopeptidase activity | Hs | molecular function | 402 | 2.59e-121 |
thiol-dependent ubiquitin-specific protease activity | Hs | molecular function | 402 | 2.59e-121 |
protein binding | Hs | molecular function | 402 | 2.59e-121 |
nucleus | Hs | cellular component | 402 | 2.59e-121 |
nucleoplasm | Hs | cellular component | 184 | 1.01e-48 |
cytoplasm | Hs | cellular component | 402 | 2.59e-121 |
lysosome | Hs | cellular component | 172 | 1.22e-43 |
endosome | Hs | cellular component | 402 | 2.59e-121 |
early endosome | Hs | cellular component | 402 | 2.59e-121 |
centrosome | Hs | cellular component | 184 | 1.01e-48 |
cytosol | Hs | cellular component | 402 | 2.59e-121 |
plasma membrane | Hs | cellular component | 402 | 2.59e-121 |
cell cortex | Hs | cellular component | 184 | 1.01e-48 |
peptidase activity | Hs | molecular function | 402 | 2.59e-121 |
cysteine-type peptidase activity | Hs | molecular function | 402 | 2.59e-121 |
endosome membrane | Hs | cellular component | 402 | 2.59e-121 |
postsynaptic density | Hs | cellular component | 402 | 2.59e-121 |
membrane | Hs | cellular component | 402 | 2.59e-121 |
hydrolase activity | Hs | molecular function | 402 | 2.59e-121 |
SH3 domain binding | Hs | molecular function | 402 | 2.59e-121 |
extrinsic component of plasma membrane | Hs | cellular component | 402 | 2.59e-121 |
cyclin binding | Hs | molecular function | 184 | 1.01e-48 |
midbody | Hs | cellular component | 402 | 2.59e-121 |
extrinsic component of endosome membrane | Hs | cellular component | 402 | 2.59e-121 |
ubiquitin protein ligase binding | Hs | molecular function | 184 | 1.01e-48 |
adenosine receptor binding | Hs | molecular function | 172 | 1.22e-43 |
thiol-dependent ubiquitinyl hydrolase activity | Hs | molecular function | 402 | 2.59e-121 |
identical protein binding | Hs | molecular function | 184 | 1.01e-48 |
dendritic spine | Hs | cellular component | 402 | 2.59e-121 |
cadherin binding | Hs | molecular function | 402 | 2.59e-121 |
metal ion binding | Hs | molecular function | 184 | 1.01e-48 |
perinuclear region of cytoplasm | Hs | cellular component | 184 | 1.01e-48 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | SUPERFAMILY | molecular function | 6.52E-9 |
ubiquitin-dependent protein catabolic process | ProSitePatterns | biological process | |
protein deubiquitination | Pfam | biological process | 8.0E-62 |
thiol-dependent ubiquitinyl hydrolase activity | Pfam | molecular function | 8.0E-62 |