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GENE CARD

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Gene Card

Best human hits

CHUK; IKBKE; TBK1

Species

M.oculata

Unique Gene ID

Moocul.g00004794

Gene Model ID

Moocul.CG.ELv1_2.S71203.g04794

Location

S71203:23459..30379

Transcript Models and Sequences

  Moocul.CG.ELv1_2.S71203.g04794.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
Prot_kinase_dom SMART Protein kinase domain
Prot_kinase_dom Pfam Protein kinase domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Prot_kinase_dom ProSiteProfiles Protein kinase domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

54 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
activation of innate immune response Hs biological process
immune system process Hs biological process
nucleic acid binding Hs molecular function
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
NF-kappaB-inducing kinase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
protein phosphorylation Hs biological process
inflammatory response Hs biological process
immune response Hs biological process
cellular response to DNA damage stimulus Hs biological process
I-kappaB kinase/NF-kappaB signaling Hs biological process
I-kappaB phosphorylation Hs biological process
IkappaB kinase activity Hs molecular function
intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
response to virus Hs biological process
endosome membrane Hs cellular component
negative regulation of gene expression Hs biological process
positive regulation of lipid storage Hs biological process
viral process Hs biological process
aggresome Hs cellular component
positive regulation of macroautophagy Hs biological process
kinase activity Hs molecular function
phosphorylation Hs biological process
PML body Hs cellular component
transferase activity Hs molecular function
peptidyl-serine phosphorylation Hs biological process
peptidyl-threonine phosphorylation Hs biological process
ubiquitin protein ligase binding Hs molecular function
mitochondrial membrane Hs cellular component
negative regulation of type I interferon production Hs biological process
positive regulation of type I interferon production Hs biological process
positive regulation of peptidyl-serine phosphorylation Hs biological process
TRIF-dependent toll-like receptor signaling pathway Hs biological process
K48-linked polyubiquitin modification-dependent protein binding Hs molecular function
NIK/NF-kappaB signaling Hs biological process
identical protein binding Hs molecular function
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
innate immune response Hs biological process
positive regulation of interferon-beta biosynthetic process Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
defense response to Gram-positive bacterium Hs biological process
phosphoprotein binding Hs molecular function
protein homooligomerization Hs biological process
defense response to virus Hs biological process
cellular response to virus Hs biological process
regulation of neuron death Hs biological process
positive regulation of xenophagy Hs biological process

GO (Blast)

29 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 355 8.59e-113
nucleic acid binding Hs molecular function 355 8.59e-113
protein kinase activity Hs molecular function 355 8.59e-113
protein serine/threonine kinase activity Hs molecular function 355 8.59e-113
NF-kappaB-inducing kinase activity Hs molecular function 325 1.13e-101
protein binding Hs molecular function 355 8.59e-113
ATP binding Hs molecular function 355 8.59e-113
nucleus Hs cellular component 325 1.13e-101
nucleoplasm Hs cellular component 355 8.59e-113
cytoplasm Hs cellular component 355 8.59e-113
cytosol Hs cellular component 355 8.59e-113
IkappaB kinase activity Hs molecular function 325 1.13e-101
IkappaB kinase complex Hs cellular component 78.2 6.66e-15
cytoplasmic side of plasma membrane Hs cellular component 78.2 6.66e-15
endosome membrane Hs cellular component 355 8.59e-113
aggresome Hs cellular component 355 8.59e-113
kinase activity Hs molecular function 355 8.59e-113
PML body Hs cellular component 325 1.13e-101
transferase activity Hs molecular function 355 8.59e-113
ubiquitin protein ligase binding Hs molecular function 325 1.13e-101
mitochondrial membrane Hs cellular component 325 1.13e-101
CD40 receptor complex Hs cellular component 78.2 6.66e-15
K48-linked polyubiquitin modification-dependent protein binding Hs molecular function 325 1.13e-101
identical protein binding Hs molecular function 355 8.59e-113
protein homodimerization activity Hs molecular function 78.2 6.66e-15
intracellular membrane-bounded organelle Hs cellular component 78.2 6.66e-15
protein heterodimerization activity Hs molecular function 78.2 6.66e-15
phosphoprotein binding Hs molecular function 355 8.59e-113
scaffold protein binding Hs molecular function 78.2 6.66e-15

GO (InterProScan)

3 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 1.9E-20
ATP binding Pfam molecular function 1.9E-20
protein phosphorylation Pfam biological process 1.9E-20