Gene Card
Best human hits
DNA2; IGHMBP2; UPF1
Species
Unique Gene ID
Moocul.g00006057
Gene Model ID
Moocul.CG.ELv1_2.S81791.g06057
Location
S81791:16817..29408
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
DNA_replication_fac_Dna2_N | Pfam | DNA replication factor Dna2, N-terminal |
Dna2 | PANTHER | Dna2 |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
DNA replication checkpoint | Hs | biological process |
nucleotide binding | Hs | molecular function |
telomere maintenance | Hs | biological process |
DNA double-strand break processing | Hs | biological process |
DNA synthesis involved in DNA repair | Hs | biological process |
strand displacement | Hs | biological process |
nuclear chromosome, telomeric region | Hs | cellular component |
DNA binding | Hs | molecular function |
DNA helicase activity | Hs | molecular function |
catalytic activity | Hs | molecular function |
helicase activity | Hs | molecular function |
nuclease activity | Hs | molecular function |
endonuclease activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
gamma DNA polymerase complex | Hs | cellular component |
DNA replication | Hs | biological process |
mitochondrial DNA replication | Hs | biological process |
DNA repair | Hs | biological process |
base-excision repair | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
metabolic process | Hs | biological process |
hydrolase activity | Hs | molecular function |
ATPase activity | Hs | molecular function |
site-specific endodeoxyribonuclease activity, specific for altered base | Hs | molecular function |
5'-flap endonuclease activity | Hs | molecular function |
DNA duplex unwinding | Hs | biological process |
DNA replication, Okazaki fragment processing | Hs | biological process |
mitochondrial nucleoid | Hs | cellular component |
DNA replication, removal of RNA primer | Hs | biological process |
5'-3' DNA helicase activity | Hs | molecular function |
single-stranded DNA-dependent ATPase activity | Hs | molecular function |
mitochondrial DNA repair | Hs | biological process |
G-quadruplex DNA unwinding | Hs | biological process |
positive regulation of DNA replication | Hs | biological process |
metal ion binding | Hs | molecular function |
iron-sulfur cluster binding | Hs | molecular function |
4 iron, 4 sulfur cluster binding | Hs | molecular function |
nucleic acid phosphodiester bond hydrolysis | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
tRNA binding | Hs | molecular function | 154 | 5.21e-38 |
nucleotide binding | Hs | molecular function | 686 | 0.0 |
nuclear chromosome, telomeric region | Hs | cellular component | 686 | 0.0 |
chromatin | Hs | cellular component | 152 | 2.23e-37 |
P-body | Hs | cellular component | 152 | 2.23e-37 |
nucleic acid binding | Hs | molecular function | 154 | 5.21e-38 |
DNA binding | Hs | molecular function | 686 | 0.0 |
DNA helicase activity | Hs | molecular function | 686 | 0.0 |
chromatin binding | Hs | molecular function | 152 | 2.23e-37 |
single-stranded DNA binding | Hs | molecular function | 154 | 5.21e-38 |
RNA binding | Hs | molecular function | 154 | 5.21e-38 |
catalytic activity | Hs | molecular function | 686 | 0.0 |
ATP-dependent RNA helicase activity | Hs | molecular function | 152 | 2.23e-37 |
helicase activity | Hs | molecular function | 686 | 0.0 |
nuclease activity | Hs | molecular function | 686 | 0.0 |
endonuclease activity | Hs | molecular function | 686 | 0.0 |
protein binding | Hs | molecular function | 686 | 0.0 |
ATP binding | Hs | molecular function | 686 | 0.0 |
nucleus | Hs | cellular component | 686 | 0.0 |
nucleoplasm | Hs | cellular component | 686 | 0.0 |
cytoplasm | Hs | cellular component | 154 | 5.21e-38 |
mitochondrion | Hs | cellular component | 686 | 0.0 |
gamma DNA polymerase complex | Hs | cellular component | 686 | 0.0 |
cytosol | Hs | cellular component | 152 | 2.23e-37 |
DNA-dependent ATPase activity | Hs | molecular function | 154 | 5.21e-38 |
transcription factor binding | Hs | molecular function | 154 | 5.21e-38 |
RNA-dependent ATPase activity | Hs | molecular function | 154 | 5.21e-38 |
zinc ion binding | Hs | molecular function | 154 | 5.21e-38 |
membrane | Hs | cellular component | 154 | 5.21e-38 |
hydrolase activity | Hs | molecular function | 686 | 0.0 |
ATPase activity | Hs | molecular function | 686 | 0.0 |
site-specific endodeoxyribonuclease activity, specific for altered base | Hs | molecular function | 686 | 0.0 |
5'-flap endonuclease activity | Hs | molecular function | 686 | 0.0 |
axon | Hs | cellular component | 154 | 5.21e-38 |
growth cone | Hs | cellular component | 154 | 5.21e-38 |
intracellular ribonucleoprotein complex | Hs | cellular component | 154 | 5.21e-38 |
ATP-dependent 5'-3' RNA helicase activity | Hs | molecular function | 154 | 5.21e-38 |
exon-exon junction complex | Hs | cellular component | 152 | 2.23e-37 |
telomeric DNA binding | Hs | molecular function | 152 | 2.23e-37 |
mitochondrial nucleoid | Hs | cellular component | 686 | 0.0 |
cell projection | Hs | cellular component | 154 | 5.21e-38 |
ribosome binding | Hs | molecular function | 154 | 5.21e-38 |
5'-3' DNA helicase activity | Hs | molecular function | 686 | 0.0 |
ATP-dependent 5'-3' DNA helicase activity | Hs | molecular function | 154 | 5.21e-38 |
single-stranded DNA-dependent ATPase activity | Hs | molecular function | 686 | 0.0 |
supraspliceosomal complex | Hs | cellular component | 152 | 2.23e-37 |
metal ion binding | Hs | molecular function | 686 | 0.0 |
iron-sulfur cluster binding | Hs | molecular function | 686 | 0.0 |
4 iron, 4 sulfur cluster binding | Hs | molecular function | 686 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
5'-flap endonuclease activity | PANTHER | molecular function | 4.6E-175 |
DNA replication, Okazaki fragment processing | PANTHER | biological process | 4.6E-175 |
single-stranded DNA-dependent ATPase activity | PANTHER | molecular function | 4.6E-175 |