Gene Card
Best human hits
SRGAP1; SRGAP2; SRGAP3
Species
Unique Gene ID
Moocul.g00007159
Gene Model ID
Moocul.CG.ELv1_2.S90133.g07159
Location
S90133:970..23507
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
14 results
| IPR Term | Analysis | Definition |
|---|---|---|
| SH3_domain | SMART | SH3 domain |
| Rho_GTPase_activation_prot | SUPERFAMILY | Rho GTPase activation protein |
| SH3_domain | Pfam | SH3 domain |
| FCH_dom | SMART | FCH domain |
| AH/BAR_dom_sf | SUPERFAMILY | AH/BAR domain superfamily |
| RhoGAP_dom | ProSiteProfiles | Rho GTPase-activating protein domain |
| F_BAR | ProSiteProfiles | F-BAR domain |
| Rho_GTPase_activation_prot | Gene3D | Rho GTPase activation protein |
| SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
| RhoGAP_dom | SMART | Rho GTPase-activating protein domain |
| AH/BAR_dom_sf | Gene3D | AH/BAR domain superfamily |
| RhoGAP_dom | Pfam | Rho GTPase-activating protein domain |
| SH3_domain | ProSiteProfiles | SH3 domain |
| FCH_dom | Pfam | FCH domain |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
43 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| GTPase activator activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| nucleoplasm | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| cytosol | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| signal transduction | Hs | biological process |
| nervous system development | Hs | biological process |
| postsynaptic density | Hs | cellular component |
| membrane | Hs | cellular component |
| lamellipodium | Hs | cellular component |
| cell junction | Hs | cellular component |
| negative regulation of cell migration | Hs | biological process |
| cytoplasmic vesicle | Hs | cellular component |
| substrate adhesion-dependent cell spreading | Hs | biological process |
| identical protein binding | Hs | molecular function |
| protein homodimerization activity | Hs | molecular function |
| cell projection | Hs | cellular component |
| dendritic spine | Hs | cellular component |
| positive regulation of GTPase activity | Hs | biological process |
| dendritic spine head | Hs | cellular component |
| synapse | Hs | cellular component |
| postsynaptic membrane | Hs | cellular component |
| phagocytic vesicle | Hs | cellular component |
| filopodium assembly | Hs | biological process |
| Rac GTPase binding | Hs | molecular function |
| neuron projection morphogenesis | Hs | biological process |
| actin filament severing | Hs | biological process |
| regulation of small GTPase mediated signal transduction | Hs | biological process |
| dendritic spine development | Hs | biological process |
| negative regulation of neuron migration | Hs | biological process |
| SH3/SH2 adaptor activity | Hs | molecular function |
| Golgi apparatus | Hs | cellular component |
| microtubule | Hs | cellular component |
| cytoskeleton organization | Hs | biological process |
| Rho protein signal transduction | Hs | biological process |
| positive regulation of signal transduction | Hs | biological process |
| growth cone | Hs | cellular component |
| negative regulation of axon extension | Hs | biological process |
| protein heterodimerization activity | Hs | molecular function |
| negative regulation of filopodium assembly | Hs | biological process |
| positive regulation of neuron migration | Hs | biological process |
GO (Blast)
21 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| GTPase activator activity | Hs | molecular function | 668 | 0.0 |
| protein binding | Hs | molecular function | 668 | 0.0 |
| nucleus | Hs | cellular component | 591 | 0.0 |
| nucleoplasm | Hs | cellular component | 591 | 0.0 |
| cytoplasm | Hs | cellular component | 668 | 0.0 |
| cytosol | Hs | cellular component | 668 | 0.0 |
| plasma membrane | Hs | cellular component | 591 | 0.0 |
| postsynaptic density | Hs | cellular component | 591 | 0.0 |
| membrane | Hs | cellular component | 591 | 0.0 |
| lamellipodium | Hs | cellular component | 591 | 0.0 |
| cell junction | Hs | cellular component | 591 | 0.0 |
| cytoplasmic vesicle | Hs | cellular component | 591 | 0.0 |
| identical protein binding | Hs | molecular function | 591 | 0.0 |
| protein homodimerization activity | Hs | molecular function | 591 | 0.0 |
| cell projection | Hs | cellular component | 591 | 0.0 |
| dendritic spine | Hs | cellular component | 591 | 0.0 |
| dendritic spine head | Hs | cellular component | 591 | 0.0 |
| synapse | Hs | cellular component | 591 | 0.0 |
| postsynaptic membrane | Hs | cellular component | 591 | 0.0 |
| phagocytic vesicle | Hs | cellular component | 591 | 0.0 |
| Rac GTPase binding | Hs | molecular function | 668 | 0.0 |
GO (InterProScan)
2 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | SUPERFAMILY | molecular function | 1.27E-16 |
| signal transduction | SMART | biological process | 2.0E-55 |
