Gene Card
Best human hits
LRP1; LRP1B; LRP6
Unique Gene ID
Cirobu.g00015307
Gene Model ID
NCBI:KH.108949500
Location
KhC5:4572903..4581564
Transcript Models and Sequences
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
10 results
| IPR Term | Analysis | Definition |
|---|---|---|
| HYR_dom | Pfam | HYR domain |
| 6-blade_b-propeller_TolB-like | Gene3D | Six-bladed beta-propeller, TolB-like |
| Kringle | Pfam | Kringle |
| Kringle-like | SUPERFAMILY | Kringle-like fold |
| Kringle | ProSiteProfiles | Kringle |
| Kringle_CS | ProSitePatterns | Kringle, conserved site |
| Kringle | SMART | Kringle |
| HYR_dom | ProSiteProfiles | HYR domain |
| Kringle_sf | Gene3D | Kringle superfamily |
| LDLR_classB_rpt | SMART | LDLR class B repeat |
GOSlim
48 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| RNA binding | Blast | molecular function |
| receptor binding | Blast | molecular function |
| calcium ion binding | Blast | molecular function |
| protein binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| nucleus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| lysosomal membrane | Blast | cellular component |
| endosome | Blast | cellular component |
| early endosome | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| integral component of plasma membrane | Blast | cellular component |
| focal adhesion | Blast | cellular component |
| cell surface | Blast | cellular component |
| protein transport | Blast | biological process |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| basolateral plasma membrane | Blast | cellular component |
| cytoplasmic vesicle | Blast | cellular component |
| identical protein binding | Blast | molecular function |
| protein homodimerization activity | Blast | molecular function |
| neuronal cell body | Blast | cellular component |
| macromolecular complex binding | Blast | molecular function |
| membrane raft | Blast | cellular component |
| synapse | Blast | cellular component |
| metal ion binding | Blast | molecular function |
| enzyme binding | Blast | molecular function |
| membrane organization | Blast | biological process |
| organelle organization | Blast | biological process |
| plasma membrane region | Blast | cellular component |
| membrane part | Blast | cellular component |
| endomembrane system | Blast | cellular component |
| kinase activity | Blast | molecular function |
| enzyme regulator activity | Blast | molecular function |
| transmembrane transport | Blast | biological process |
| intracellular organelle part | Blast | cellular component |
| whole membrane | Blast | cellular component |
| bounding membrane of organelle | Blast | cellular component |
| cell surface receptor signaling pathway | Blast | biological process |
| cell-cell signaling | Blast | biological process |
| transmembrane signaling receptor activity | Blast | molecular function |
| macromolecular complex | Blast | cellular component |
| anion binding | Blast | molecular function |
| carbohydrate derivative binding | Blast | molecular function |
| signaling receptor activity | Blast | molecular function |
| plasma membrane part | Blast | cellular component |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
55 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| protease binding | Hs | molecular function | 112 | 6.81e-25 |
| RNA binding | Hs | molecular function | 112 | 6.81e-25 |
| receptor activity | Hs | molecular function | 112 | 6.81e-25 |
| low-density lipoprotein receptor activity | Hs | molecular function | 112 | 6.81e-25 |
| scavenger receptor activity | Hs | molecular function | 112 | 6.81e-25 |
| receptor binding | Hs | molecular function | 107 | 3.32e-23 |
| frizzled binding | Hs | molecular function | 107 | 3.32e-23 |
| calcium ion binding | Hs | molecular function | 115 | 1.03e-25 |
| protein binding | Hs | molecular function | 115 | 1.03e-25 |
| extracellular region | Hs | cellular component | 107 | 3.32e-23 |
| nucleus | Hs | cellular component | 112 | 6.81e-25 |
| cytoplasm | Hs | cellular component | 112 | 6.81e-25 |
| lysosomal membrane | Hs | cellular component | 112 | 6.81e-25 |
| endosome | Hs | cellular component | 112 | 6.81e-25 |
| early endosome | Hs | cellular component | 112 | 6.81e-25 |
| endoplasmic reticulum | Hs | cellular component | 107 | 3.32e-23 |
| Golgi apparatus | Hs | cellular component | 107 | 3.32e-23 |
| plasma membrane | Hs | cellular component | 112 | 6.81e-25 |
| integral component of plasma membrane | Hs | cellular component | 112 | 6.81e-25 |
| caveola | Hs | cellular component | 107 | 3.32e-23 |
| clathrin-coated pit | Hs | cellular component | 112 | 6.81e-25 |
| focal adhesion | Hs | cellular component | 112 | 6.81e-25 |
| cell surface | Hs | cellular component | 107 | 3.32e-23 |
| membrane | Hs | cellular component | 115 | 1.03e-25 |
| integral component of membrane | Hs | cellular component | 115 | 1.03e-25 |
| basolateral plasma membrane | Hs | cellular component | 112 | 6.81e-25 |
| alpha-2 macroglobulin receptor activity | Hs | molecular function | 112 | 6.81e-25 |
| Wnt-protein binding | Hs | molecular function | 107 | 3.32e-23 |
| kinase inhibitor activity | Hs | molecular function | 107 | 3.32e-23 |
| toxin transporter activity | Hs | molecular function | 107 | 3.32e-23 |
| clathrin-coated vesicle | Hs | cellular component | 112 | 6.81e-25 |
| apolipoprotein receptor activity | Hs | molecular function | 112 | 6.81e-25 |
| dendrite | Hs | cellular component | 112 | 6.81e-25 |
| endocytic vesicle membrane | Hs | cellular component | 112 | 6.81e-25 |
| cytoplasmic vesicle | Hs | cellular component | 107 | 3.32e-23 |
| early endosome membrane | Hs | cellular component | 107 | 3.32e-23 |
| clathrin heavy chain binding | Hs | molecular function | 112 | 6.81e-25 |
| apolipoprotein binding | Hs | molecular function | 112 | 6.81e-25 |
| identical protein binding | Hs | molecular function | 107 | 3.32e-23 |
| protein homodimerization activity | Hs | molecular function | 107 | 3.32e-23 |
| Wnt-activated receptor activity | Hs | molecular function | 107 | 3.32e-23 |
| lipoprotein transporter activity | Hs | molecular function | 112 | 6.81e-25 |
| neuronal cell body | Hs | cellular component | 112 | 6.81e-25 |
| receptor complex | Hs | cellular component | 115 | 1.03e-25 |
| heparan sulfate proteoglycan binding | Hs | molecular function | 112 | 6.81e-25 |
| macromolecular complex binding | Hs | molecular function | 112 | 6.81e-25 |
| membrane raft | Hs | cellular component | 107 | 3.32e-23 |
| synapse | Hs | cellular component | 107 | 3.32e-23 |
| metal ion binding | Hs | molecular function | 112 | 6.81e-25 |
| lipoprotein particle receptor binding | Hs | molecular function | 112 | 6.81e-25 |
| coreceptor activity involved in Wnt signaling pathway | Hs | molecular function | 107 | 3.32e-23 |
| plasma membrane protein complex | Hs | cellular component | 112 | 6.81e-25 |
| coreceptor activity involved in canonical Wnt signaling pathway | Hs | molecular function | 107 | 3.32e-23 |
| Wnt-Frizzled-LRP5/6 complex | Hs | cellular component | 107 | 3.32e-23 |
| Wnt signalosome | Hs | cellular component | 107 | 3.32e-23 |
| GO Term | Analysis | Type | e-value |
|---|
