Gene Card
Best human hits
LRP1; LRP6
Species
Unique Gene ID
Phfumi.g00000239
Gene Model ID
Phfumi.CG.MTP2014.S11.g00239
Location
S11:159243..170131
Transcript Models and Sequences
Phfumi.CG.MTP2014.S11.g00239.01.t
Phfumi.CG.MTP2014.S11.g00239.02.t
n/a
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Click here to see the tree inference method
InterPro
13 results
| IPR Term | Analysis | Definition |
|---|---|---|
| LDLR_classB_rpt | ProSiteProfiles | LDLR class B repeat |
| Kringle | Pfam | Kringle |
| Kringle-like | SUPERFAMILY | Kringle-like fold |
| HYR_dom | Pfam | HYR domain |
| Kringle_sf | Gene3D | Kringle superfamily |
| Kringle_CS | ProSitePatterns | Kringle, conserved site |
| Kringle | CDD | Kringle |
| 6-blade_b-propeller_TolB-like | Gene3D | Six-bladed beta-propeller, TolB-like |
| Kringle | SMART | Kringle |
| EGF-like_dom | SMART | EGF-like domain |
| Kringle | ProSiteProfiles | Kringle |
| HYR_dom | ProSiteProfiles | HYR domain |
| LDLR_classB_rpt | SMART | LDLR class B repeat |
GOSlim
48 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| RNA binding | Blast | molecular function |
| receptor binding | Blast | molecular function |
| calcium ion binding | Blast | molecular function |
| protein binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| nucleus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| lysosomal membrane | Blast | cellular component |
| endosome | Blast | cellular component |
| early endosome | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| integral component of plasma membrane | Blast | cellular component |
| focal adhesion | Blast | cellular component |
| cell surface | Blast | cellular component |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| basolateral plasma membrane | Blast | cellular component |
| cytoplasmic vesicle | Blast | cellular component |
| identical protein binding | Blast | molecular function |
| protein homodimerization activity | Blast | molecular function |
| neuronal cell body | Blast | cellular component |
| macromolecular complex binding | Blast | molecular function |
| membrane raft | Blast | cellular component |
| synapse | Blast | cellular component |
| metal ion binding | Blast | molecular function |
| enzyme binding | Blast | molecular function |
| membrane organization | Blast | biological process |
| organelle organization | Blast | biological process |
| plasma membrane region | Blast | cellular component |
| membrane part | Blast | cellular component |
| endomembrane system | Blast | cellular component |
| kinase activity | Blast | molecular function |
| enzyme regulator activity | Blast | molecular function |
| transmembrane transport | Blast | biological process |
| intracellular organelle part | Blast | cellular component |
| whole membrane | Blast | cellular component |
| bounding membrane of organelle | Blast | cellular component |
| cell surface receptor signaling pathway | Blast | biological process |
| cell-cell signaling | Blast | biological process |
| transmembrane signaling receptor activity | Blast | molecular function |
| protein transport | Blast | biological process |
| macromolecular complex | Blast | cellular component |
| anion binding | Blast | molecular function |
| carbohydrate derivative binding | Blast | molecular function |
| signaling receptor activity | Blast | molecular function |
| plasma membrane part | Blast | cellular component |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
55 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| protease binding | Hs | molecular function | 103 | 3.56e-22 |
| RNA binding | Hs | molecular function | 103 | 3.56e-22 |
| receptor activity | Hs | molecular function | 103 | 3.56e-22 |
| low-density lipoprotein receptor activity | Hs | molecular function | 103 | 3.51e-22 |
| scavenger receptor activity | Hs | molecular function | 103 | 3.56e-22 |
| receptor binding | Hs | molecular function | 103 | 3.51e-22 |
| frizzled binding | Hs | molecular function | 103 | 3.51e-22 |
| calcium ion binding | Hs | molecular function | 103 | 3.56e-22 |
| protein binding | Hs | molecular function | 103 | 3.51e-22 |
| extracellular region | Hs | cellular component | 103 | 3.51e-22 |
| nucleus | Hs | cellular component | 103 | 3.56e-22 |
| cytoplasm | Hs | cellular component | 103 | 3.56e-22 |
| lysosomal membrane | Hs | cellular component | 103 | 3.56e-22 |
| endosome | Hs | cellular component | 103 | 3.56e-22 |
| early endosome | Hs | cellular component | 103 | 3.51e-22 |
| endoplasmic reticulum | Hs | cellular component | 103 | 3.51e-22 |
| Golgi apparatus | Hs | cellular component | 103 | 3.51e-22 |
| plasma membrane | Hs | cellular component | 103 | 3.51e-22 |
| integral component of plasma membrane | Hs | cellular component | 103 | 3.56e-22 |
| caveola | Hs | cellular component | 103 | 3.51e-22 |
| clathrin-coated pit | Hs | cellular component | 103 | 3.56e-22 |
| focal adhesion | Hs | cellular component | 103 | 3.56e-22 |
| cell surface | Hs | cellular component | 103 | 3.51e-22 |
| membrane | Hs | cellular component | 103 | 3.51e-22 |
| integral component of membrane | Hs | cellular component | 103 | 3.51e-22 |
| basolateral plasma membrane | Hs | cellular component | 103 | 3.56e-22 |
| alpha-2 macroglobulin receptor activity | Hs | molecular function | 103 | 3.56e-22 |
| Wnt-protein binding | Hs | molecular function | 103 | 3.51e-22 |
| kinase inhibitor activity | Hs | molecular function | 103 | 3.51e-22 |
| toxin transporter activity | Hs | molecular function | 103 | 3.51e-22 |
| clathrin-coated vesicle | Hs | cellular component | 103 | 3.56e-22 |
| apolipoprotein receptor activity | Hs | molecular function | 103 | 3.56e-22 |
| dendrite | Hs | cellular component | 103 | 3.56e-22 |
| endocytic vesicle membrane | Hs | cellular component | 103 | 3.56e-22 |
| cytoplasmic vesicle | Hs | cellular component | 103 | 3.51e-22 |
| early endosome membrane | Hs | cellular component | 103 | 3.51e-22 |
| clathrin heavy chain binding | Hs | molecular function | 103 | 3.56e-22 |
| apolipoprotein binding | Hs | molecular function | 103 | 3.51e-22 |
| identical protein binding | Hs | molecular function | 103 | 3.51e-22 |
| protein homodimerization activity | Hs | molecular function | 103 | 3.51e-22 |
| Wnt-activated receptor activity | Hs | molecular function | 103 | 3.51e-22 |
| lipoprotein transporter activity | Hs | molecular function | 103 | 3.56e-22 |
| neuronal cell body | Hs | cellular component | 103 | 3.51e-22 |
| receptor complex | Hs | cellular component | 103 | 3.51e-22 |
| heparan sulfate proteoglycan binding | Hs | molecular function | 103 | 3.56e-22 |
| macromolecular complex binding | Hs | molecular function | 103 | 3.56e-22 |
| membrane raft | Hs | cellular component | 103 | 3.51e-22 |
| synapse | Hs | cellular component | 103 | 3.51e-22 |
| metal ion binding | Hs | molecular function | 103 | 3.56e-22 |
| lipoprotein particle receptor binding | Hs | molecular function | 103 | 3.56e-22 |
| coreceptor activity involved in Wnt signaling pathway | Hs | molecular function | 103 | 3.51e-22 |
| plasma membrane protein complex | Hs | cellular component | 103 | 3.56e-22 |
| coreceptor activity involved in canonical Wnt signaling pathway | Hs | molecular function | 103 | 3.51e-22 |
| Wnt-Frizzled-LRP5/6 complex | Hs | cellular component | 103 | 3.51e-22 |
| Wnt signalosome | Hs | cellular component | 103 | 3.51e-22 |
| GO Term | Analysis | Type | e-value |
|---|
