Gene Card
Best human hits
BMP2; BMP4; GDF10
Species
Unique Gene ID
Phfumi.g00003624
Gene Model ID
Phfumi.CG.MTP2014.S1364.g03624
Location
S1364:2972..11558
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
TGF-b_C | Pfam | Transforming growth factor-beta, C-terminal |
TGF-b_C | ProSiteProfiles | Transforming growth factor-beta, C-terminal |
TGFb_CS | ProSitePatterns | Transforming growth factor beta, conserved site |
TGF-beta-rel | PANTHER | Transforming growth factor-beta-related |
TGF-b_propeptide | Pfam | TGF-beta, propeptide |
TGF-b_C | SMART | Transforming growth factor-beta, C-terminal |
Cystine-knot_cytokine | Gene3D | Cystine-knot cytokine |
Cystine-knot_cytokine | SUPERFAMILY | Cystine-knot cytokine |
GO Term | Annotation Origin | Type |
---|---|---|
receptor binding | Orthology | molecular function |
protein binding | Blast | molecular function |
extracellular region | Orthology | cellular component |
extracellular space | Orthology | cellular component |
endoplasmic reticulum lumen | Blast | cellular component |
protein phosphorylation | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
multicellular organism development | Orthology | biological process |
cell surface | Blast | cellular component |
cell differentiation | Orthology | biological process |
regulation of apoptotic process | Orthology | biological process |
intracellular membrane-bounded organelle | Blast | cellular component |
protein heterodimerization activity | Blast | molecular function |
cell development | Orthology | biological process |
oxidation-reduction process | Blast | biological process |
extracellular exosome | Orthology | cellular component |
system development | Orthology | biological process |
molecular function regulator | Orthology | molecular function |
regulation of signal transduction | Orthology | biological process |
signaling receptor activity | Orthology | molecular function |
cell surface receptor signaling pathway | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
regulation of molecular function | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
extracellular region part | Orthology | cellular component |
intracellular signal transduction | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
animal organ development | Orthology | biological process |
catalytic activity | Blast | molecular function |
anion binding | Blast | molecular function |
carbohydrate derivative binding | Blast | molecular function |
dephosphorylation | Blast | biological process |
hydrolase activity | Blast | molecular function |
enzyme binding | Blast | molecular function |
enzyme activator activity | Blast | molecular function |
chemotaxis | Blast | biological process |
integral component of plasma membrane | Blast | cellular component |
macromolecular complex | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
skeletal system development | Hs | biological process |
ossification | Hs | biological process |
osteoblast differentiation | Hs | biological process |
receptor binding | Hs | molecular function |
cytokine activity | Hs | molecular function |
transforming growth factor beta receptor binding | Hs | molecular function |
extracellular region | Hs | cellular component |
extracellular space | Hs | cellular component |
transforming growth factor beta receptor signaling pathway | Hs | biological process |
cell-cell signaling | Hs | biological process |
multicellular organism development | Hs | biological process |
growth factor activity | Hs | molecular function |
regulation of receptor activity | Hs | biological process |
positive regulation of pathway-restricted SMAD protein phosphorylation | Hs | biological process |
cell differentiation | Hs | biological process |
BMP signaling pathway | Hs | biological process |
extracellular matrix | Hs | cellular component |
extracellular exosome | Hs | cellular component |
regulation of apoptotic process | Hs | biological process |
regulation of MAPK cascade | Hs | biological process |
fat cell differentiation | Hs | biological process |
negative regulation of osteoblast differentiation | Hs | biological process |
cell development | Hs | biological process |
cartilage development | Hs | biological process |
SMAD protein signal transduction | Hs | biological process |
BMP receptor binding | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
retinol dehydrogenase activity | Hs | molecular function | 128 | 4.54e-32 |
receptor binding | Hs | molecular function | 128 | 4.54e-32 |
cytokine activity | Hs | molecular function | 140 | 1.03e-35 |
transforming growth factor beta receptor binding | Hs | molecular function | 140 | 1.03e-35 |
protein binding | Hs | molecular function | 128 | 4.54e-32 |
extracellular region | Hs | cellular component | 140 | 1.03e-35 |
proteinaceous extracellular matrix | Hs | cellular component | 126 | 1.93e-31 |
extracellular space | Hs | cellular component | 140 | 1.03e-35 |
endoplasmic reticulum lumen | Hs | cellular component | 126 | 1.93e-31 |
growth factor activity | Hs | molecular function | 140 | 1.03e-35 |
heparin binding | Hs | molecular function | 126 | 1.93e-31 |
cell surface | Hs | cellular component | 128 | 4.54e-32 |
phosphatase activator activity | Hs | molecular function | 128 | 4.54e-32 |
extracellular matrix | Hs | cellular component | 140 | 1.03e-35 |
co-receptor binding | Hs | molecular function | 128 | 4.54e-32 |
chemoattractant activity | Hs | molecular function | 126 | 1.93e-31 |
intracellular membrane-bounded organelle | Hs | cellular component | 128 | 4.54e-32 |
SMAD binding | Hs | molecular function | 128 | 4.54e-32 |
protein heterodimerization activity | Hs | molecular function | 128 | 4.54e-32 |
BMP receptor binding | Hs | molecular function | 128 | 4.54e-32 |
BMP receptor complex | Hs | cellular component | 128 | 4.54e-32 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
growth factor activity | SMART | molecular function | 6.4E-45 |